| UHGV-1366296_1 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-1366296_1 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-1366296_1 | UniRef90 | UniRef90_UPI000DE4F8FA | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1366296_1 | eggNOG-mapper | 1391647.AVSV01000003_gene1798 | PFAM C-5 cytosine-specific DNA methylase | NA |
| UHGV-1366296_1 | PADLOC | MTase_II_00058 | Type II methyltransferase | RM |
| UHGV-1366296_1 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-1366296_1 | NCBIFam | TIGR00675.1 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1366296_1 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-1366296_1 | Structural annotation | PF00145, MF_01872, TIGR00675, COG0270 | NA | NA |
| UHGV-1366296_2 | PHROG | phrog_7778 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-1366296_2 | UniRef90 | UniRef90_UPI00189BC90F | NA | NA |
| UHGV-1366296_2 | eggNOG-mapper | 1304284.L21TH_2610 | NA | NA |
| UHGV-1366296_2 | Pfam | PF05037 | NA | DUF669 |
| UHGV-1366296_2 | Structural annotation | PF05037 | NA | NA |
| UHGV-1366296_4 | PHROG | phrog_2872 | Sak4-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-1366296_4 | UniRef90 | UniRef90_A0A348ZC83 | ATP-binding protein | NA |
| UHGV-1366296_4 | eggNOG-mapper | 257310.BB3533 | NA | NA |
| UHGV-1366296_4 | Pfam | PF13479 | AAA domain | AAA_24 |
| UHGV-1366296_4 | Structural annotation | PF13479, MF_00350, TIGR01618, COG0468 | NA | NA |
| UHGV-1366296_5 | PHROG | phrog_8097 | exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1366296_5 | UniRef90 | UniRef90_UPI0003B19C47 | PD-(D/E)XK nuclease family protein | NA |
| UHGV-1366296_5 | eggNOG-mapper | 203119.Cthe_1737 | AAA domain | NA |
| UHGV-1366296_5 | Pfam | PF12705 | PD-(D/E)XK nuclease superfamily | PDDEXK_1 |
| UHGV-1366296_5 | COG | COG2887 | RecB family exonuclease | NA |
| UHGV-1366296_5 | Structural annotation | PF12684, TIGR01896, COG4343 | NA | NA |
| UHGV-1366296_6 | PHROG | phrog_93 | endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1366296_6 | UniRef90 | UniRef90_A0A6H1F1P0 | VRR-NUC domain-containing protein | NA |
| UHGV-1366296_6 | eggNOG-mapper | 562981.HMPREF0428_01004 | VRR_NUC | NA |
| UHGV-1366296_6 | Pfam | PF01870 | Archaeal holliday junction resolvase (hjc) | Hjc |
| UHGV-1366296_6 | COG | COG1591 | Holliday junction resolvase Hjc, archaeal type | NA |
| UHGV-1366296_6 | Structural annotation | PF01870, MF_01490, NF002581, COG1591 | NA | NA |
| UHGV-1366296_7 | PHROG | phrog_6244 | NA | unknown function |
| UHGV-1366296_7 | UniRef90 | UniRef90_A0A7W3XTD8 | Chromosome segregation ATPase | NA |
| UHGV-1366296_7 | eggNOG-mapper | 935836.JAEL01000005_gene2723 | NA | NA |
| UHGV-1366296_11 | KOfam | K14440 | SMARCAL1, HARP; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:5.6.2.-] | NA |
| UHGV-1366296_11 | PHROG | phrog_62 | DNA helicase | DNA, RNA and nucleotide metabolism |
| UHGV-1366296_11 | UniRef90 | UniRef90_UPI000D9FC9EE | DEAD/DEAH box helicase | NA |
| UHGV-1366296_11 | eggNOG-mapper | 1280692.AUJL01000009_gene2982 | snf2 family | NA |
| UHGV-1366296_11 | PADLOC | DpdE_00003 | DpdE | DPD |
| UHGV-1366296_11 | Pfam | PF00176 | SNF2-related domain | SNF2-rel_dom |
| UHGV-1366296_11 | Pfam | PF00271 | Helicase conserved C-terminal domain | Helicase_C |
| UHGV-1366296_11 | COG | COG0553 | Superfamily II DNA or RNA helicase, SNF2 family | NA |
| UHGV-1366296_11 | Structural annotation | PF00176, PF00271, MF_01821, NF041790, COG0553 | NA | NA |
| UHGV-1366296_14 | UniRef90 | UniRef90_A0A417K735 | XRE family transcriptional regulator | NA |
| UHGV-1366296_14 | eggNOG-mapper | 536233.CLO_0954 | NA | NA |
| UHGV-1366296_16 | KOfam | K18830 | pezA; HTH-type transcriptional regulator / antitoxin PezA | NA |
| UHGV-1366296_16 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-1366296_16 | UniRef90 | UniRef90_A0A417K795 | XRE family transcriptional regulator | NA |
| UHGV-1366296_16 | eggNOG-mapper | 1121333.JMLH01000042_gene2742 | Peptidase S24-like | NA |
| UHGV-1366296_16 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1366296_16 | COG | COG1974 | SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) | NA |
| UHGV-1366296_16 | Structural annotation | PF12844, MF_00535, NF041951, COG1396 | NA | NA |
| UHGV-1366296_17 | KOfam | K06400 | spoIVCA; site-specific DNA recombinase | NA |
| UHGV-1366296_17 | PHROG | phrog_95 | integrase | integration and excision |
| UHGV-1366296_17 | UniRef90 | UniRef90_UPI0007748959 | recombinase family protein | NA |
| UHGV-1366296_17 | eggNOG-mapper | 1378168.N510_03180 | resolvase | NA |
| UHGV-1366296_17 | Pfam | PF00239 | Resolvase, N terminal domain | Resolvase |
| UHGV-1366296_17 | Pfam | PF13408 | Recombinase zinc beta ribbon domain | Zn_ribbon_recom |
| UHGV-1366296_17 | COG | COG1961 | Site-specific DNA recombinase SpoIVCA/DNA invertase PinE | NA |
| UHGV-1366296_17 | Structural annotation | PF00239, NF041201, COG1961 | NA | NA |
| UHGV-1366296_20 | KOfam | K22299 | rghR; HTH-type transcriptional regulator, competence development regulator | NA |
| UHGV-1366296_20 | PHROG | phrog_3 | transcriptional repressor | transcription regulation |
| UHGV-1366296_20 | UniRef90 | UniRef90_F4XEQ8 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-1366296_20 | eggNOG-mapper | 1519439.JPJG01000059_gene1955 | Cro/C1-type HTH DNA-binding domain | NA |
| UHGV-1366296_20 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1366296_20 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1366296_20 | Structural annotation | PF01381, NF041951, COG1396 | NA | NA |
| UHGV-1366296_25 | COG | COG3613 | Nucleoside 2-deoxyribosyltransferase | NA |
| UHGV-1366296_27 | PHROG | phrog_4534 | NA | unknown function |
| UHGV-1366296_29 | PHROG | phrog_1220 | head protein | head and packaging |
| UHGV-1366296_29 | eggNOG-mapper | 742740.HMPREF9474_02259 | NA | NA |
| UHGV-1366296_29 | Structural annotation | PF03906, PF20747 | NA | NA |
| UHGV-1366296_30 | PHROG | phrog_538 | minor tail protein | tail |
| UHGV-1366296_30 | UniRef90 | UniRef90_UPI0004813F81 | siphovirus ReqiPepy6 Gp37-like family protein | NA |
| UHGV-1366296_30 | eggNOG-mapper | 742733.HMPREF9469_05018 | Siphovirus ReqiPepy6 Gp37-like protein | NA |
| UHGV-1366296_30 | Pfam | PF14594 | Siphovirus ReqiPepy6 Gp37-like protein | Sipho_Gp37 |
| UHGV-1366296_30 | Structural annotation | PF14594, TIGR01665, COG4926 | NA | NA |
| UHGV-1366296_31 | PHROG | phrog_33 | distal tail protein Dit | tail |
| UHGV-1366296_31 | UniRef90 | UniRef90_A0A415G8B5 | Phage tail family protein | NA |
| UHGV-1366296_31 | eggNOG-mapper | 411468.CLOSCI_00539 | COG NOG18823 non supervised orthologous group | NA |
| UHGV-1366296_31 | Pfam | PF05709 | Phage tail protein RIFT-related domain | Sipho_tail |
| UHGV-1366296_31 | COG | COG4722 | Phage-related protein YomH | NA |
| UHGV-1366296_31 | Structural annotation | PF20753, PF16774, TIGR01633, COG4722 | NA | NA |
| UHGV-1366296_32 | PHROG | phrog_23464 | NA | unknown function |
| UHGV-1366296_32 | eggNOG-mapper | 665950.HMPREF1025_02660 | phage tail tape measure protein | NA |
| UHGV-1366296_32 | COG | COG5283 | Phage-related tail protein | NA |
| UHGV-1366296_34 | PHROG | phrog_88 | major tail protein | tail |
| UHGV-1366296_34 | NCBIFam | TIGR01603.1 | major tail protein | NA |
| UHGV-1366296_34 | Structural annotation | PF04630, TIGR01603, COG3498 | NA | NA |
| UHGV-1366296_35 | Structural annotation | PF05657 | NA | NA |
| UHGV-1366296_36 | Structural annotation | TIGR01725 | NA | NA |
| UHGV-1366296_37 | UniRef90 | UniRef90_R6Z5T8 | Putative phage head-tail adaptor | NA |
| UHGV-1366296_37 | Structural annotation | PF05521, TIGR01563, COG5614 | NA | NA |
| UHGV-1366296_38 | UniRef90 | UniRef90_A0A843EB61 | Phage head-tail connector protein | NA |
| UHGV-1366296_38 | Structural annotation | PF05135, TIGR01560 | NA | NA |
| UHGV-1366296_44 | PHROG | phrog_10 | major head protein | head and packaging |
| UHGV-1366296_44 | UniRef90 | UniRef90_A0A374RUK3 | Phage major capsid protein | NA |
| UHGV-1366296_44 | eggNOG-mapper | 1536774.H70357_10630 | Phage capsid family | NA |
| UHGV-1366296_44 | Pfam | PF05065 | Phage capsid family | Phage_capsid |
| UHGV-1366296_44 | NCBIFam | TIGR01554.2 | phage major capsid protein | NA |
| UHGV-1366296_44 | COG | COG4653 | Predicted phage phi-C31 gp36 major capsid-like protein | NA |
| UHGV-1366296_44 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-1366296_45 | KOfam | K06904 | NA | NA |
| UHGV-1366296_45 | PHROG | phrog_80 | head maturation protease | head and packaging |
| UHGV-1366296_45 | UniRef90 | UniRef90_A0A415G8A3 | HK97 family phage prohead protease | NA |
| UHGV-1366296_45 | eggNOG-mapper | 1123263.AUKY01000046_gene468 | Phage prohead protease, HK97 family | NA |
| UHGV-1366296_45 | Pfam | PF04586 | Caudovirus prohead serine protease | Peptidase_S78 |
| UHGV-1366296_45 | NCBIFam | TIGR01543.1 | HK97 family phage prohead protease | NA |
| UHGV-1366296_45 | COG | COG3740 | Phage head maturation protease | NA |
| UHGV-1366296_45 | Structural annotation | PF04586, TIGR01543, COG3740 | NA | NA |
| UHGV-1366296_47 | Structural annotation | PF08948, MF_01537, NF007541, COG3123 | NA | NA |
| UHGV-1366296_51 | PHROG | phrog_12 | portal protein | head and packaging |
| UHGV-1366296_51 | UniRef90 | UniRef90_UPI00156EE181 | phage portal protein | NA |
| UHGV-1366296_51 | eggNOG-mapper | 642492.Clole_1856 | Portal protein | NA |
| UHGV-1366296_51 | Pfam | PF04860 | Phage portal protein | Phage_portal |
| UHGV-1366296_51 | COG | COG4695 | Phage portal protein BeeE | NA |
| UHGV-1366296_51 | Structural annotation | PF04860, MF_04135, TIGR01537, COG4695 | NA | NA |
| UHGV-1366296_52 | PHROG | phrog_7339 | DNA repair exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1366296_52 | UniRef90 | UniRef90_A0A521DUK9 | Calcineurin-like phosphoesterase superfamily domain-containing protein | NA |
| UHGV-1366296_52 | eggNOG-mapper | 1150474.JQJI01000006_gene784 | metallophosphoesterase | NA |
| UHGV-1366296_52 | Pfam | PF00149 | Calcineurin-like phosphoesterase | Metallophos |
| UHGV-1366296_52 | COG | COG1408 | Predicted phosphohydrolase, MPP superfamily | NA |
| UHGV-1366296_52 | Structural annotation | PF12850, MF_00325, NF003118, COG1311 | NA | NA |
| UHGV-1366296_53 | PHROG | phrog_9 | terminase large subunit | head and packaging |
| UHGV-1366296_53 | UniRef90 | UniRef90_A0A316T832 | Terminase | NA |
| UHGV-1366296_53 | eggNOG-mapper | 1211817.CCAT010000007_gene1040 | Terminase | NA |
| UHGV-1366296_53 | Pfam | PF03354 | Terminase large subunit, ATPase domain | TerL_ATPase |
| UHGV-1366296_53 | COG | COG4626 | Phage terminase-like protein, large subunit, contains N-terminal HTH domain | NA |
| UHGV-1366296_53 | Structural annotation | PF20441, PF03354, MF_04145, TIGR01547, COG4626 | NA | NA |
| UHGV-1366296_55 | UniRef90 | UniRef90_UPI0005C7DF53 | HNH endonuclease | NA |
| UHGV-1366296_55 | eggNOG-mapper | 1536769.P40081_01050 | HNH nucleases | NA |
| UHGV-1366296_55 | Pfam | PF01844 | HNH endonuclease | HNH |
| UHGV-1366296_55 | COG | COG1403 | 5-methylcytosine-specific restriction endonuclease McrA | NA |
| UHGV-1366296_55 | Structural annotation | PF13671, MF_03171, NF005251, NF008448, COG4639 | NA | NA |
| UHGV-1366296_56 | PHROG | phrog_309 | terminase small subunit | head and packaging |
| UHGV-1366296_56 | UniRef90 | UniRef90_A0A7Y9D6F7 | Transposase-like protein | NA |
| UHGV-1366296_56 | eggNOG-mapper | 290402.Cbei_1634 | transposase activity | NA |
| UHGV-1366296_56 | COG | COG2963 | Transposase InsE and inactivated derivatives | NA |
| UHGV-1366296_56 | Structural annotation | PF07141 | NA | NA |
| UHGV-1366296_57 | PHROG | phrog_1863 | NA | unknown function |
| UHGV-1366296_57 | eggNOG-mapper | 665956.HMPREF1032_03922 | NA | NA |
| UHGV-1366296_58 | PHROG | phrog_1129 | holin | lysis |
| UHGV-1366296_58 | UniRef90 | UniRef90_R7FCA0 | Phage holin | NA |
| UHGV-1366296_58 | eggNOG-mapper | 1304866.K413DRAFT_0135 | Phage holin family Hol44, in holin superfamily V | NA |
| UHGV-1366296_58 | Pfam | PF16079 | Phage holin family Hol44, in holin superfamily V | Phage_holin_5_2 |
| UHGV-1366296_58 | Structural annotation | PF16079 | NA | NA |
| UHGV-1366296_59 | KOfam | K06919 | K06919; putative DNA primase/helicase | NA |
| UHGV-1366296_59 | PHROG | phrog_864 | DNA primase | DNA, RNA and nucleotide metabolism |
| UHGV-1366296_59 | UniRef90 | UniRef90_A0A259V1C2 | SF3 helicase domain-containing protein | NA |
| UHGV-1366296_59 | eggNOG-mapper | 742740.HMPREF9474_02364 | Phage plasmid primase, P4 family | NA |
| UHGV-1366296_59 | Pfam | PF08706 | D5 N terminal like | D5_N |
| UHGV-1366296_59 | Pfam | PF19263 | NA | DUF5906 |
| UHGV-1366296_59 | NCBIFam | TIGR01613.1 | phage/plasmid primase, P4 family | NA |
| UHGV-1366296_59 | COG | COG3378 | DNA primase, phage- or plasmid-associated | NA |
| UHGV-1366296_59 | Structural annotation | PF19263, PF08706, PF03288, PF09250, MF_04000, TIGR01613, COG3378 | NA | NA |
| UHGV-1366296_61 | eggNOG-mapper | 1408438.JADD01000021_gene397 | NA | NA |
| UHGV-1366296_62 | dbAPIS | APIS029 | Tad2 is a "sponge" that sequesters the immune signaling molecules produced by Thoeris TIR-domain proteins in response to phage. | NA |
| UHGV-1366296_62 | Structural annotation | PF11195 | NA | NA |
| UHGV-1366296_63 | PHROG | phrog_1252 | DNA polymerase | DNA, RNA and nucleotide metabolism |
| UHGV-1366296_63 | UniRef90 | UniRef90_A3DG77 | DNA polymerase B region | NA |
| UHGV-1366296_63 | eggNOG-mapper | 203119.Cthe_1735 | DNA polymerase elongation subunit (Family B) | NA |
| UHGV-1366296_63 | COG | COG0417 | DNA polymerase B elongation subunit | NA |
| UHGV-1366296_63 | Structural annotation | PF08490, MF_04100, TIGR00592, COG0417 | NA | NA |
| UHGV-1366296_64 | PHROG | phrog_2044 | RNA polymerase beta subunit | DNA, RNA and nucleotide metabolism |
| UHGV-1366296_64 | eggNOG-mapper | 796940.HMPREF9628_00162 | NA | NA |
| UHGV-1366296_64 | Structural annotation | MF_00337, NF010671, COG1722 | NA | NA |
| UHGV-1366296_65 | PHROG | phrog_1891 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1366296_65 | UniRef90 | UniRef90_A0A354MDA7 | HNH endonuclease | NA |
| UHGV-1366296_65 | eggNOG-mapper | 546275.FUSPEROL_02054 | HNH endonuclease | NA |
| UHGV-1366296_65 | Pfam | PF13392 | HNH endonuclease | HNH_3 |
| UHGV-1366296_65 | Structural annotation | PF13392 | NA | NA |