| UHGV-1369567_2 | Structural annotation | PF08962 | NA | NA |
| UHGV-1369567_3 | eggNOG-mapper | 926549.KI421517_gene2307 | NA | NA |
| UHGV-1369567_5 | KOfam | K23779 | sutR; XRE family transcriptional regulator, regulator of sulfur utilization | NA |
| UHGV-1369567_5 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1369567_5 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1369567_5 | Structural annotation | PF01381, MF_00535, NF041951, COG3655 | NA | NA |
| UHGV-1369567_6 | UniRef90 | UniRef90_UPI000C15ACB8 | helix-turn-helix domain-containing protein | NA |
| UHGV-1369567_6 | eggNOG-mapper | 997884.HMPREF1068_03266 | NA | NA |
| UHGV-1369567_6 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-1369567_6 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1369567_6 | Structural annotation | PF01381, MF_00535, NF000090, COG1476 | NA | NA |
| UHGV-1369567_9 | PHROG | phrog_1501 | NA | unknown function |
| UHGV-1369567_9 | UniRef90 | UniRef90_R6EVM2 | NA | NA |
| UHGV-1369567_9 | eggNOG-mapper | 679935.Alfi_0537 | NA | NA |
| UHGV-1369567_9 | Pfam | PF18925 | NA | DUF5675 |
| UHGV-1369567_9 | Structural annotation | PF18925 | NA | NA |
| UHGV-1369567_10 | UniRef90 | UniRef90_UPI001C49131D | NA | NA |
| UHGV-1369567_10 | eggNOG-mapper | 411479.BACUNI_00733 | NA | NA |
| UHGV-1369567_10 | Pfam | PF14301 | NA | DUF4376 |
| UHGV-1369567_10 | Structural annotation | PF14301 | NA | NA |
| UHGV-1369567_11 | KOfam | K00986 | ltrA; RNA-directed DNA polymerase [EC:2.7.7.49] | NA |
| UHGV-1369567_11 | PHROG | phrog_1423 | Reverse transcriptase | DNA, RNA and nucleotide metabolism |
| UHGV-1369567_11 | UniRef90 | UniRef90_UPI001C2C8EC1 | RNA-directed DNA polymerase | NA |
| UHGV-1369567_11 | eggNOG-mapper | 1123037.AUDE01000030_gene3191 | Reverse transcriptase (RNA-dependent DNA polymerase) | NA |
| UHGV-1369567_11 | PADLOC | icity0040 | RT (reverse transcriptase) | CRISPR-CAS |
| UHGV-1369567_11 | Pfam | PF00078 | Reverse transcriptase (RNA-dependent DNA polymerase) | RVT_1 |
| UHGV-1369567_11 | COG | COG3344 | Retron-type reverse transcriptase | NA |
| UHGV-1369567_11 | Structural annotation | PF00078, MF_04065, TIGR04416, COG3344 | NA | NA |
| UHGV-1369567_12 | Structural annotation | PF05635, NF033474 | NA | NA |
| UHGV-1369567_13 | Structural annotation | PF10794, PF20942, PF13620, NF040788, COG2351 | NA | NA |
| UHGV-1369567_14 | PHROG | phrog_38044 | NA | unknown function |
| UHGV-1369567_14 | eggNOG-mapper | 762982.HMPREF9442_01191 | cellulase activity | NA |
| UHGV-1369567_14 | Pfam | PF02018 | Carbohydrate binding domain | CBM_4_9 |
| UHGV-1369567_14 | COG | COG4733 | Phage-related protein, tail protein J | NA |
| UHGV-1369567_14 | Structural annotation | PF00629, PF20073, NF033675 | NA | NA |
| UHGV-1369567_19 | Pfam | PF20459 | NA | DUF6712 |
| UHGV-1369567_19 | Structural annotation | PF20459 | NA | NA |
| UHGV-1369567_21 | KOfam | K00571 | E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] | NA |
| UHGV-1369567_21 | PHROG | phrog_18293 | methyltransferase | other |
| UHGV-1369567_21 | UniRef90 | UniRef90_UPI001F1587D7 | site-specific DNA-methyltransferase | NA |
| UHGV-1369567_21 | eggNOG-mapper | 1408823.AXUS01000035_gene1787 | Belongs to the N(4) N(6)-methyltransferase family | NA |
| UHGV-1369567_21 | PADLOC | MTase_II_00037 | Type II methyltransferase | RM |
| UHGV-1369567_21 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-1369567_21 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-1369567_21 | Structural annotation | PF01555, NF008572, COG0863 | NA | NA |
| UHGV-1369567_22 | KOfam | K00571 | E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] | NA |
| UHGV-1369567_22 | PHROG | phrog_12862 | NA | unknown function |
| UHGV-1369567_22 | UniRef90 | UniRef90_A0A658JP37 | Site-specific DNA-methyltransferase (Fragment) | NA |
| UHGV-1369567_22 | eggNOG-mapper | 1527692.A0A096XVB1_9CAUD | helicase activity | NA |
| UHGV-1369567_22 | PADLOC | MTase_II_00037 | Type II methyltransferase | RM |
| UHGV-1369567_23 | eggNOG-mapper | 1235803.C825_03414 | NA | NA |
| UHGV-1369567_23 | Structural annotation | PF05136, MF_04135, TIGR01540, COG5518 | NA | NA |
| UHGV-1369567_24 | Structural annotation | PF13619 | NA | NA |
| UHGV-1369567_25 | PHROG | phrog_200 | lipoprotein | other |
| UHGV-1369567_25 | UniRef90 | UniRef90_A0A3R6J4I4 | SPFH domain-containing protein | NA |
| UHGV-1369567_25 | eggNOG-mapper | 1122989.KB898587_gene2262 | SPFH domain / Band 7 family | NA |
| UHGV-1369567_25 | Pfam | PF01145 | SPFH domain / Band 7 family | Band_7 |
| UHGV-1369567_25 | COG | COG0330 | Regulator of protease activity HflC, stomatin/prohibitin superfamily | NA |
| UHGV-1369567_25 | Structural annotation | PF01145, MF_01562, NF008181, COG2268 | NA | NA |
| UHGV-1369567_26 | UniRef90 | UniRef90_A0A6I1S5I8 | GNAT family N-acetyltransferase | NA |
| UHGV-1369567_26 | Pfam | PF00583 | Acetyltransferase (GNAT) family | Acetyltransf_1 |
| UHGV-1369567_26 | Structural annotation | PF13673, MF_02018, NF000487, COG3153 | NA | NA |
| UHGV-1369567_29 | Structural annotation | PF18195, COG5475 | NA | NA |
| UHGV-1369567_32 | PHROG | phrog_8684 | NA | unknown function |
| UHGV-1369567_32 | UniRef90 | UniRef90_UPI001F45D98B | YopX family protein | NA |
| UHGV-1369567_32 | eggNOG-mapper | 1347393.HG726022_gene3579 | YopX protein | NA |
| UHGV-1369567_32 | Pfam | PF09643 | YopX protein | YopX |
| UHGV-1369567_32 | NCBIFam | TIGR01671.1 | phage conserved hypothetical protein TIGR01671 | NA |
| UHGV-1369567_32 | Structural annotation | PF09643, TIGR01671 | NA | NA |
| UHGV-1369567_33 | PHROG | phrog_11581 | NA | unknown function |
| UHGV-1369567_33 | eggNOG-mapper | 470145.BACCOP_01179 | NA | NA |
| UHGV-1369567_34 | PHROG | phrog_21668 | NA | unknown function |
| UHGV-1369567_35 | Structural annotation | PF08605, MF_01194, NF010729 | NA | NA |
| UHGV-1369567_37 | PHROG | phrog_874 | NA | unknown function |
| UHGV-1369567_37 | eggNOG-mapper | 1121098.HMPREF1534_01095 | NA | NA |
| UHGV-1369567_42 | Structural annotation | PF10628 | NA | NA |
| UHGV-1369567_45 | KOfam | K21703 | cbbR, cmpR, ndhR; LysR family transcriptional regulator, low CO2-responsive transcriptional regulator | NA |
| UHGV-1369567_45 | PHROG | phrog_3736 | NA | unknown function |
| UHGV-1369567_45 | UniRef90 | UniRef90_A0A353E8E6 | HTH lysR-type domain-containing protein | NA |
| UHGV-1369567_45 | eggNOG-mapper | 1317122.ATO12_13660 | LysR substrate binding domain | NA |
| UHGV-1369567_45 | Pfam | PF00126 | Bacterial regulatory helix-turn-helix protein, lysR family | HTH_1 |
| UHGV-1369567_45 | Pfam | PF03466 | LysR substrate binding domain | LysR_substrate |
| UHGV-1369567_45 | COG | COG0583 | DNA-binding transcriptional regulator, LysR family | NA |
| UHGV-1369567_45 | Structural annotation | PF03466, PF00126, MF_01233, NF040786, COG0583 | NA | NA |
| UHGV-1369567_46 | Structural annotation | TIGR01603, COG5437 | NA | NA |
| UHGV-1369567_47 | Structural annotation | PF05065, PF18998, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-1369567_48 | KOfam | K21511 | GPC; capsid assembly protease [EC:3.4.21.-] | NA |
| UHGV-1369567_48 | PHROG | phrog_53 | head maturation protease | head and packaging |
| UHGV-1369567_48 | UniRef90 | UniRef90_A0A2L2WN07 | Signal peptide peptidase SppA, 36K type | NA |
| UHGV-1369567_48 | eggNOG-mapper | 1236504.HMPREF2132_01855 | serine-type peptidase activity | NA |
| UHGV-1369567_48 | Pfam | PF01343 | Peptidase family S49 | Peptidase_S49 |
| UHGV-1369567_48 | COG | COG0616 | Periplasmic serine protease, ClpP class | NA |
| UHGV-1369567_48 | Structural annotation | PF01343, MF_00444, TIGR00706, COG0616 | NA | NA |
| UHGV-1369567_49 | Structural annotation | PF11550, COG5437 | NA | NA |
| UHGV-1369567_52 | PHROG | phrog_229 | MazG-like pyrophosphatase | other |
| UHGV-1369567_52 | UniRef90 | UniRef90_A0A353E7W6 | MazG domain-containing protein | NA |
| UHGV-1369567_52 | eggNOG-mapper | 1236504.HMPREF2132_01780 | Mazg nucleotide pyrophosphohydrolase | NA |
| UHGV-1369567_52 | Pfam | PF03819 | MazG nucleotide pyrophosphohydrolase domain | MazG |
| UHGV-1369567_52 | COG | COG1694 | NTP pyrophosphatase, house-cleaning of non-canonical NTPs | NA |
| UHGV-1369567_52 | Structural annotation | TIGR03188, COG1694 | NA | NA |
| UHGV-1369567_53 | KOfam | K03465 | thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148] | NA |
| UHGV-1369567_53 | PHROG | phrog_85 | thymidylate synthase | DNA, RNA and nucleotide metabolism |
| UHGV-1369567_53 | UniRef90 | UniRef90_A0A8F0WBE8 | Flavin-dependent thymidylate synthase | NA |
| UHGV-1369567_53 | eggNOG-mapper | 1236504.HMPREF2132_01775 | thymidylate synthase (FAD) activity | NA |
| UHGV-1369567_53 | Pfam | PF02511 | Thymidylate synthase complementing protein | Thy1 |
| UHGV-1369567_53 | COG | COG1351 | Thymidylate synthase ThyX, FAD-dependent family | NA |
| UHGV-1369567_53 | Structural annotation | PF02511, MF_01408, TIGR02170, COG1351 | NA | NA |
| UHGV-1369567_54 | KOfam | K00942 | gmk, GUK1; guanylate kinase [EC:2.7.4.8] | NA |
| UHGV-1369567_54 | PHROG | phrog_1815 | guanylate kinase | other |
| UHGV-1369567_54 | UniRef90 | UniRef90_A0A354WXC5 | Guanylate kinase | NA |
| UHGV-1369567_54 | eggNOG-mapper | 742727.HMPREF9447_00732 | Guanylate kinase | NA |
| UHGV-1369567_54 | Pfam | PF00625 | Guanylate kinase | Guanylate_kin |
| UHGV-1369567_54 | COG | COG0194 | Guanylate kinase | NA |
| UHGV-1369567_54 | Structural annotation | PF00625, MF_00328, TIGR03263, COG0194 | NA | NA |
| UHGV-1369567_55 | UniRef90 | UniRef90_A0A2L2WND9 | Primase C terminal 2 | NA |
| UHGV-1369567_55 | eggNOG-mapper | 1236504.HMPREF2132_01765 | Primase C terminal 2 (PriCT-2) | NA |
| UHGV-1369567_55 | PADLOC | drt-cluster64 | DRT | DRT |
| UHGV-1369567_55 | Pfam | PF08800 | BT4734-like, N-terminal domain | BT4734-like_N |
| UHGV-1369567_55 | Pfam | PF08707 | Primase C terminal 2 (PriCT-2) | PriCT_2 |
| UHGV-1369567_55 | COG | COG5545 | Predicted P-loop ATPase and inactivated derivatives | NA |
| UHGV-1369567_55 | Structural annotation | PF08800, NF040562 | NA | NA |
| UHGV-1369567_56 | KOfam | K10421 | CLIP1, RSN; CAP-Gly domain-containing linker protein 1 | NA |
| UHGV-1369567_56 | PHROG | phrog_28 | tail length tape measure protein | tail |
| UHGV-1369567_56 | UniRef90 | UniRef90_A0A2L2WS53 | PhageMin_Tail domain-containing protein | NA |
| UHGV-1369567_56 | eggNOG-mapper | 1236504.HMPREF2132_01670 | tail tape measure protein, TP901 family | NA |
| UHGV-1369567_56 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-1369567_56 | NCBIFam | TIGR01760.1 | phage tail tape measure protein | NA |
| UHGV-1369567_56 | COG | COG5283 | Phage-related tail protein | NA |
| UHGV-1369567_58 | Structural annotation | PF20765 | NA | NA |
| UHGV-1369567_59 | UniRef90 | UniRef90_UPI001C2BD57F | phage holin family protein | NA |
| UHGV-1369567_59 | eggNOG-mapper | 457424.BFAG_02443 | NA | NA |
| UHGV-1369567_59 | Pfam | PF05105 | Bacteriophage holin family | Phage_holin_4_1 |
| UHGV-1369567_59 | Structural annotation | TIGR01593 | NA | NA |
| UHGV-1369567_62 | KOfam | K00390 | cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] | NA |
| UHGV-1369567_62 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-1369567_62 | UniRef90 | UniRef90_UPI000D8D5A98 | phosphoadenosine phosphosulfate reductase family protein | NA |
| UHGV-1369567_62 | eggNOG-mapper | 357276.EL88_11445 | Phosphoadenosine phosphosulfate reductase family | NA |
| UHGV-1369567_62 | PADLOC | BrxP_00001 | BrxP | BREX |
| UHGV-1369567_62 | Pfam | PF01507 | Phosphoadenosine phosphosulfate reductase family | PAPS_reduct |
| UHGV-1369567_62 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-1369567_62 | Structural annotation | PF01507, MF_00064, NF006327, COG0175 | NA | NA |
| UHGV-1369567_64 | PHROG | phrog_799 | DNA methyltransferase | other |
| UHGV-1369567_64 | UniRef90 | UniRef90_A0A096B9T1 | Conjugal transfer protein | NA |
| UHGV-1369567_64 | eggNOG-mapper | 1236504.HMPREF2132_01885 | DNA restriction-modification system | NA |
| UHGV-1369567_64 | COG | COG0827 | Adenine-specific DNA N6-methylase | NA |
| UHGV-1369567_64 | Structural annotation | PF06325, MF_01947, NF000058, COG2263 | NA | NA |
| UHGV-1369567_66 | eggNOG-mapper | 1002367.HMPREF0673_02207 | NA | NA |
| UHGV-1369567_66 | Structural annotation | PF04466, PF20441, MF_04145, TIGR01547, COG1783 | NA | NA |
| UHGV-1369567_73 | KOfam | K02338 | dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] | NA |
| UHGV-1369567_73 | PHROG | phrog_947 | DNA polymerase processivity factor | DNA, RNA and nucleotide metabolism |
| UHGV-1369567_73 | UniRef90 | UniRef90_A0A7X6VW07 | Beta sliding clamp | NA |
| UHGV-1369567_73 | eggNOG-mapper | 1236504.HMPREF2132_01710 | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria | NA |
| UHGV-1369567_73 | Pfam | PF00712 | DNA polymerase III beta subunit, N-terminal domain | DNA_pol3_beta |
| UHGV-1369567_73 | Pfam | PF02768 | DNA polymerase III beta subunit, C-terminal domain | DNA_pol3_beta_3 |
| UHGV-1369567_73 | COG | COG0592 | DNA polymerase III sliding clamp (beta) subunit, PCNA homolog | NA |
| UHGV-1369567_73 | Structural annotation | PF02768, PF00712, PF02767, MF_00317, TIGR00663, COG0592 | NA | NA |
| UHGV-1369567_77 | UniRef90 | UniRef90_A0A096AGU9 | FHA domain-containing protein | NA |
| UHGV-1369567_77 | eggNOG-mapper | 1236504.HMPREF2132_01700 | DNA primase activity | NA |
| UHGV-1369567_77 | COG | COG0358 | DNA primase (bacterial type) | NA |
| UHGV-1369567_77 | Structural annotation | PF05272, PF01807, MF_00974, MF_00016, NF005477, COG3378, COG0358 | NA | NA |
| UHGV-1369567_79 | PHROG | phrog_255 | exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1369567_79 | UniRef90 | UniRef90_A0A355U3Z6 | NA | NA |
| UHGV-1369567_79 | eggNOG-mapper | 1236504.HMPREF2132_01690 | DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease | NA |
| UHGV-1369567_79 | Pfam | PF16473 | 3'-5' exoribonuclease Rv2179c-like domain | Rv2179c-like |
| UHGV-1369567_79 | COG | COG0847 | DNA polymerase III, epsilon subunit or related 3'-5' exonuclease | NA |
| UHGV-1369567_79 | Structural annotation | PF16473, MF_00157, TIGR01298, COG5018 | NA | NA |
| UHGV-1369567_81 | Structural annotation | COG3655 | NA | NA |
| UHGV-1369567_82 | Structural annotation | PF17457 | NA | NA |
| UHGV-1369567_85 | UniRef90 | UniRef90_A0A353E5D0 | Rep_3 domain-containing protein (Fragment) | NA |
| UHGV-1369567_85 | eggNOG-mapper | 1122983.BAJY01000004_gene1777 | Initiator RepB protein | NA |
| UHGV-1369567_85 | COG | COG5527 | Protein involved in initiation of plasmid replication | NA |
| UHGV-1369567_85 | Structural annotation | PF20964, PF01051, NF038290, COG5527 | NA | NA |
| UHGV-1369567_86 | Structural annotation | PF03869, NF010302, COG3905 | NA | NA |
| UHGV-1369567_87 | KOfam | K03496 | parA, soj; chromosome partitioning protein | NA |
| UHGV-1369567_87 | PHROG | phrog_164 | ParA-like partition protein | DNA, RNA and nucleotide metabolism |
| UHGV-1369567_87 | UniRef90 | UniRef90_A0A095Z6L5 | AAA_31 domain-containing protein | NA |
| UHGV-1369567_87 | eggNOG-mapper | 1236504.HMPREF2132_02105 | CobQ CobB MinD ParA nucleotide binding domain | NA |
| UHGV-1369567_87 | Pfam | PF13614 | AAA domain | AAA_31 |
| UHGV-1369567_87 | COG | COG1192 | ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ | NA |
| UHGV-1369567_87 | Structural annotation | PF13614, MF_00533, NF041283, COG1192 | NA | NA |
| UHGV-1369567_88 | KOfam | K01972 | E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2] | NA |
| UHGV-1369567_88 | PHROG | phrog_3869 | NAD-dependent DNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-1369567_88 | UniRef90 | UniRef90_A0A521P3I1 | DNA ligase | NA |
| UHGV-1369567_88 | eggNOG-mapper | 42256.RradSPS_0101 | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA | NA |
| UHGV-1369567_88 | Pfam | PF01653 | NAD-dependent DNA ligase adenylation domain | DNA_ligase_aden |
| UHGV-1369567_88 | Pfam | PF03120 | NAD-dependent DNA ligase OB-fold domain | DNA_ligase_OB |
| UHGV-1369567_88 | COG | COG0272 | NAD-dependent DNA ligase | NA |
| UHGV-1369567_88 | Structural annotation | PF01653, PF03120, MF_01588, NF005932, COG0272 | NA | NA |
| UHGV-1369567_89 | Structural annotation | PF06289, COG1582 | NA | NA |
| UHGV-1369567_94 | Structural annotation | PF08863, TIGR02383, COG4568 | NA | NA |
| UHGV-1369567_95 | COG | COG2982 | NA | NA |
| UHGV-1369567_98 | PHROG | phrog_37559 | NA | unknown function |
| UHGV-1369567_99 | KOfam | K03427 | hsdM; type I restriction enzyme M protein [EC:2.1.1.72] | NA |
| UHGV-1369567_99 | PHROG | phrog_5696 | NA | unknown function |
| UHGV-1369567_99 | UniRef90 | UniRef90_A0A5B2TVV4 | N-6 DNA methylase | NA |
| UHGV-1369567_99 | eggNOG-mapper | 997884.HMPREF1068_00007 | COG0286 Type I restriction-modification system methyltransferase subunit | NA |
| UHGV-1369567_99 | PADLOC | MTase_I_00005 | Type I methyltransferase | RM |
| UHGV-1369567_99 | Pfam | PF02384 | N-6 DNA Methylase | N6_Mtase |
| UHGV-1369567_99 | COG | COG0286 | Type I restriction-modification system, DNA methylase subunit | NA |
| UHGV-1369567_99 | Structural annotation | COG0286 | NA | NA |