| UHGV-1374187_1 | PHROG | phrog_374 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1374187_1 | UniRef90 | UniRef90_UPI001C3AB864 | Transcriptional regulator | NA |
| UHGV-1374187_1 | eggNOG-mapper | 397291.C804_06294 | transposase activity | NA |
| UHGV-1374187_1 | COG | COG2963 | Transposase InsE and inactivated derivatives | NA |
| UHGV-1374187_1 | Structural annotation | PF17375 | NA | NA |
| UHGV-1374187_2 | PHROG | phrog_1770 | Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-1374187_2 | UniRef90 | UniRef90_A0A7W1N8Z0 | Holliday junction endonuclease | NA |
| UHGV-1374187_2 | eggNOG-mapper | 329726.AM1_4255 | Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group | NA |
| UHGV-1374187_2 | COG | COG0817 | Holliday junction resolvasome RuvABC endonuclease subunit RuvC | NA |
| UHGV-1374187_2 | Structural annotation | PF16921, MF_00034, NF000711, COG0817 | NA | NA |
| UHGV-1374187_3 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-1374187_3 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-1374187_3 | UniRef90 | UniRef90_A0A1C5KYC3 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1374187_3 | eggNOG-mapper | 718252.FP2_16350 | C-5 cytosine-specific DNA methylase | NA |
| UHGV-1374187_3 | PADLOC | oMTase_00004 | orphan methyltransferase | RM |
| UHGV-1374187_3 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-1374187_3 | NCBIFam | TIGR00675.1 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1374187_3 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-1374187_4 | PHROG | phrog_16304 | NA | unknown function |
| UHGV-1374187_4 | UniRef90 | UniRef90_UPI001E560709 | NA | NA |
| UHGV-1374187_4 | eggNOG-mapper | 755731.Clo1100_1616 | Phage replisome organizer | NA |
| UHGV-1374187_4 | Pfam | PF19808 | NA | DUF6291 |
| UHGV-1374187_4 | COG | COG3935 | DNA replication protein DnaD | NA |
| UHGV-1374187_4 | Structural annotation | PF19808 | NA | NA |
| UHGV-1374187_5 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-1374187_5 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-1374187_5 | UniRef90 | UniRef90_A0A352RPR0 | Single-stranded DNA-binding protein | NA |
| UHGV-1374187_5 | eggNOG-mapper | 693746.OBV_19910 | Single-strand binding protein family | NA |
| UHGV-1374187_5 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-1374187_5 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-1374187_5 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-1374187_5 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-1374187_5 | Structural annotation | PF00436, MF_00984, NF005241, COG0629 | NA | NA |
| UHGV-1374187_6 | PHROG | phrog_7370 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1374187_6 | UniRef90 | UniRef90_UPI000933A555 | HNH endonuclease | NA |
| UHGV-1374187_6 | eggNOG-mapper | 1232449.BAHV02000016_gene1841 | HNH nucleases | NA |
| UHGV-1374187_6 | Pfam | PF01844 | HNH endonuclease | HNH |
| UHGV-1374187_7 | PHROG | phrog_72 | NinB/ Orf homologous recombination mediator | DNA, RNA and nucleotide metabolism |
| UHGV-1374187_7 | UniRef90 | UniRef90_A0A8D9PDS2 | NinB protein | NA |
| UHGV-1374187_7 | eggNOG-mapper | 445972.ANACOL_01825 | NA | NA |
| UHGV-1374187_7 | Structural annotation | PF05772 | NA | NA |
| UHGV-1374187_8 | PHROG | phrog_659 | Sak-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-1374187_8 | UniRef90 | UniRef90_UPI001E5A6693 | NA | NA |
| UHGV-1374187_8 | eggNOG-mapper | 1507.HMPREF0262_00431 | NA | NA |
| UHGV-1374187_8 | Pfam | PF06378 | NA | DUF1071 |
| UHGV-1374187_8 | Structural annotation | PF06378, COG4712 | NA | NA |
| UHGV-1374187_12 | PHROG | phrog_5781 | NA | unknown function |
| UHGV-1374187_12 | UniRef90 | UniRef90_A0A2V2GDQ1 | Nucleoside 2-deoxyribosyltransferase | NA |
| UHGV-1374187_12 | eggNOG-mapper | 573061.Clocel_3558 | NA | NA |
| UHGV-1374187_12 | Pfam | PF14359 | NA | DUF4406 |
| UHGV-1374187_12 | COG | COG3613 | Nucleoside 2-deoxyribosyltransferase | NA |
| UHGV-1374187_12 | Structural annotation | PF14359, MF_03036, TIGR02133, COG3613 | NA | NA |
| UHGV-1374187_18 | KOfam | K22300 | dicA; HTH-type transcriptional regulator, cell division transcriptional repressor | NA |
| UHGV-1374187_18 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-1374187_18 | UniRef90 | UniRef90_A0A844DFR0 | Helix-turn-helix domain-containing protein | NA |
| UHGV-1374187_18 | eggNOG-mapper | 748224.HMPREF9436_01444 | NA | NA |
| UHGV-1374187_18 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1374187_18 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1374187_21 | eggNOG-mapper | 428127.EUBDOL_00130 | sequence-specific DNA binding | NA |
| UHGV-1374187_21 | COG | COG1476 | DNA-binding transcriptional regulator, XRE-family HTH domain | NA |
| UHGV-1374187_21 | Structural annotation | PF13443, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-1374187_22 | KOfam | K06400 | spoIVCA; site-specific DNA recombinase | NA |
| UHGV-1374187_22 | PHROG | phrog_95 | integrase | integration and excision |
| UHGV-1374187_22 | UniRef90 | UniRef90_A0A3A9ED02 | Site-specific recombinase | NA |
| UHGV-1374187_22 | eggNOG-mapper | 1378168.N510_03180 | resolvase | NA |
| UHGV-1374187_22 | Pfam | PF00239 | Resolvase, N terminal domain | Resolvase |
| UHGV-1374187_22 | Pfam | PF13408 | Recombinase zinc beta ribbon domain | Zn_ribbon_recom |
| UHGV-1374187_22 | COG | COG1961 | Site-specific DNA recombinase SpoIVCA/DNA invertase PinE | NA |
| UHGV-1374187_22 | Structural annotation | PF00239, NF041201, COG1961 | NA | NA |
| UHGV-1374187_23 | eggNOG-mapper | 1226322.HMPREF1545_00079 | NA | NA |
| UHGV-1374187_24 | eggNOG-mapper | 476272.RUMHYD_01772 | NA | NA |
| UHGV-1374187_24 | Structural annotation | PF12510 | NA | NA |
| UHGV-1374187_25 | PHROG | phrog_20016 | NA | unknown function |
| UHGV-1374187_25 | UniRef90 | UniRef90_A0A285PT46 | Tumour necrosis factor-like domain | NA |
| UHGV-1374187_25 | eggNOG-mapper | 1226322.HMPREF1545_00077 | NA | NA |
| UHGV-1374187_25 | Structural annotation | PF18573, NF033147 | NA | NA |
| UHGV-1374187_26 | PHROG | phrog_16490 | NA | unknown function |
| UHGV-1374187_26 | eggNOG-mapper | 1408437.JNJN01000043_gene803 | NA | NA |
| UHGV-1374187_27 | PHROG | phrog_22984 | NA | unknown function |
| UHGV-1374187_28 | PHROG | phrog_21718 | NA | unknown function |
| UHGV-1374187_28 | eggNOG-mapper | 397290.C810_05210 | NA | NA |
| UHGV-1374187_29 | PHROG | phrog_3754 | NA | unknown function |
| UHGV-1374187_29 | eggNOG-mapper | 476272.RUMHYD_01764 | NA | NA |
| UHGV-1374187_30 | UniRef90 | UniRef90_A0A8D9PDT6 | Transcriptional regulatory protein | NA |
| UHGV-1374187_32 | PHROG | phrog_1129 | holin | lysis |
| UHGV-1374187_32 | UniRef90 | UniRef90_A0A3R8INC9 | Enolase | NA |
| UHGV-1374187_32 | eggNOG-mapper | 1007096.BAGW01000036_gene2663 | Phage holin family Hol44, in holin superfamily V | NA |
| UHGV-1374187_32 | Pfam | PF16079 | Phage holin family Hol44, in holin superfamily V | Phage_holin_5_2 |
| UHGV-1374187_32 | Structural annotation | PF06946 | NA | NA |
| UHGV-1374187_33 | PHROG | phrog_37604 | NA | unknown function |
| UHGV-1374187_33 | eggNOG-mapper | 585501.HMPREF6123_0817 | NA | NA |
| UHGV-1374187_34 | KOfam | K07273 | acm; lysozyme | NA |
| UHGV-1374187_34 | PHROG | phrog_291 | endolysin | lysis |
| UHGV-1374187_34 | UniRef90 | UniRef90_A0A3R6RNG6 | Lyzozyme M1 (1,4-beta-N-acetylmuramidase) | NA |
| UHGV-1374187_34 | eggNOG-mapper | 411474.COPEUT_02639 | hydrolase, family 25 | NA |
| UHGV-1374187_34 | Pfam | PF01183 | Glycosyl hydrolases family 25 | Glyco_hydro_25 |
| UHGV-1374187_34 | Pfam | PF08230 | CW_7 repeat | CW_7 |
| UHGV-1374187_34 | COG | COG3023 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD | NA |
| UHGV-1374187_34 | Structural annotation | PF01183, COG3757 | NA | NA |
| UHGV-1374187_36 | PHROG | phrog_9534 | head protein | head and packaging |
| UHGV-1374187_36 | eggNOG-mapper | 748224.HMPREF9436_00702 | COG NOG18825 non supervised orthologous group | NA |
| UHGV-1374187_36 | Structural annotation | PF21567 | NA | NA |
| UHGV-1374187_37 | PHROG | phrog_538 | minor tail protein | tail |
| UHGV-1374187_37 | UniRef90 | UniRef90_UPI001C113FEF | siphovirus ReqiPepy6 Gp37-like family protein | NA |
| UHGV-1374187_37 | eggNOG-mapper | 931626.Awo_c34990 | Siphovirus ReqiPepy6 Gp37-like protein | NA |
| UHGV-1374187_37 | Pfam | PF14594 | Siphovirus ReqiPepy6 Gp37-like protein | Sipho_Gp37 |
| UHGV-1374187_37 | Structural annotation | PF14594, TIGR01665, COG4926 | NA | NA |
| UHGV-1374187_38 | PHROG | phrog_36410 | NA | unknown function |
| UHGV-1374187_38 | UniRef90 | UniRef90_UPI001C0FCFFA | phage tail family protein | NA |
| UHGV-1374187_38 | eggNOG-mapper | 411471.SUBVAR_06982 | Phage tail protein | NA |
| UHGV-1374187_38 | Structural annotation | PF16774, TIGR01633, COG4722 | NA | NA |
| UHGV-1374187_39 | PHROG | phrog_23464 | NA | unknown function |
| UHGV-1374187_39 | eggNOG-mapper | 665950.HMPREF1025_02660 | phage tail tape measure protein | NA |
| UHGV-1374187_39 | COG | COG5283 | Phage-related tail protein | NA |
| UHGV-1374187_39 | Structural annotation | PF20155, MF_04138 | NA | NA |
| UHGV-1374187_41 | PHROG | phrog_885 | major tail protein | tail |
| UHGV-1374187_41 | UniRef90 | UniRef90_A0A843J9F0 | Ig-like domain-containing protein | NA |
| UHGV-1374187_41 | eggNOG-mapper | 1504822.CCNO01000012_gene492 | NA | NA |
| UHGV-1374187_41 | Structural annotation | PF06488, TIGR01603, COG5437 | NA | NA |
| UHGV-1374187_42 | UniRef90 | UniRef90_A0A415JI88 | NA | NA |
| UHGV-1374187_42 | Structural annotation | PF11367 | NA | NA |
| UHGV-1374187_43 | PHROG | phrog_17977 | NA | unknown function |
| UHGV-1374187_43 | Pfam | PF05521 | Phage head-tail joining protein | Phage_H_T_join |
| UHGV-1374187_43 | NCBIFam | TIGR01563.1 | phage head closure protein | NA |
| UHGV-1374187_43 | Structural annotation | PF07405, TIGR01563, COG5614 | NA | NA |
| UHGV-1374187_45 | PHROG | phrog_267 | major head protein | head and packaging |
| UHGV-1374187_45 | UniRef90 | UniRef90_A0A3Q9B9E4 | P22 coat protein-protein 5 domain protein | NA |
| UHGV-1374187_45 | eggNOG-mapper | 877414.ATWA01000001_gene909 | P22 coat protein-protein 5 domain protein | NA |
| UHGV-1374187_45 | Pfam | PF19821 | Phage capsid protein | Phage_capsid_2 |
| UHGV-1374187_45 | Structural annotation | PF19821, MF_04119, TIGR04387, COG4653 | NA | NA |
| UHGV-1374187_46 | UniRef90 | UniRef90_A0A6B9SU02 | Fibronectin autolysin | NA |
| UHGV-1374187_46 | Structural annotation | PF06810 | NA | NA |
| UHGV-1374187_47 | PHROG | phrog_5 | tail completion or Neck1 protein | connector |
| UHGV-1374187_47 | UniRef90 | UniRef90_UPI0015C5E40B | HK97 gp10 family phage protein | NA |
| UHGV-1374187_47 | eggNOG-mapper | 683837.lse_1605 | NA | NA |
| UHGV-1374187_47 | Pfam | PF04883 | Bacteriophage HK97-gp10, putative tail-component | HK97-gp10_like |
| UHGV-1374187_47 | Structural annotation | PF20039, TIGR01725, COG5005 | NA | NA |
| UHGV-1374187_48 | PHROG | phrog_35328 | NA | unknown function |
| UHGV-1374187_49 | PHROG | phrog_2468 | head morphogenesis | head and packaging |
| UHGV-1374187_49 | UniRef90 | UniRef90_A0A4D7AUA1 | Phage head morphogenesis protein | NA |
| UHGV-1374187_49 | eggNOG-mapper | 1235792.C808_05364 | Phage minor capsid protein 2 | NA |
| UHGV-1374187_49 | Pfam | PF04233 | Phage Mu protein F like protein | Phage_Mu_F |
| UHGV-1374187_49 | COG | COG2369 | NA | NA |
| UHGV-1374187_49 | Structural annotation | PF04233, PF21814, TIGR01641, COG2369 | NA | NA |
| UHGV-1374187_50 | PHROG | phrog_64 | portal protein | head and packaging |
| UHGV-1374187_50 | UniRef90 | UniRef90_UPI0018A8A301 | phage portal protein | NA |
| UHGV-1374187_50 | eggNOG-mapper | 673376.F2VHW1_9CAUD | Phage portal protein, SPP1 Gp6-like | NA |
| UHGV-1374187_50 | Pfam | PF05133 | Phage portal protein, SPP1 Gp6-like | Phage_prot_Gp6 |
| UHGV-1374187_50 | Structural annotation | PF05133, MF_04120, TIGR01538, COG3567 | NA | NA |
| UHGV-1374187_51 | PHROG | phrog_38 | terminase large subunit | head and packaging |
| UHGV-1374187_51 | UniRef90 | UniRef90_UPI00166CA12B | terminase family protein | NA |
| UHGV-1374187_51 | eggNOG-mapper | 1140001.I571_01829 | NA | NA |
| UHGV-1374187_51 | Structural annotation | PF17289, PF05876, MF_04147, NF033889, COG5323 | NA | NA |
| UHGV-1374187_54 | KOfam | K07319 | yhdJ; adenine-specific DNA-methyltransferase [EC:2.1.1.72] | NA |
| UHGV-1374187_54 | PHROG | phrog_498 | DNA methyltransferase | other |
| UHGV-1374187_54 | UniRef90 | UniRef90_UPI0012DE0D94 | site-specific DNA-methyltransferase | NA |
| UHGV-1374187_54 | eggNOG-mapper | 1423758.BN55_01455 | DNA methylase | NA |
| UHGV-1374187_54 | PADLOC | MTase_II_00015 | Type II methyltransferase | RM |
| UHGV-1374187_54 | Pfam | PF02195 | ParB/Sulfiredoxin domain | ParBc |
| UHGV-1374187_54 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-1374187_54 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-1374187_54 | Structural annotation | PF01555, MF_00786, NF010253, COG0863 | NA | NA |
| UHGV-1374187_55 | PHROG | phrog_36 | transcriptional regulator | transcription regulation |
| UHGV-1374187_55 | UniRef90 | UniRef90_UPI001C10AB33 | NA | NA |
| UHGV-1374187_55 | eggNOG-mapper | 428125.CLOLEP_01806 | NA | NA |
| UHGV-1374187_55 | Structural annotation | PF07374, TIGR01636 | NA | NA |
| UHGV-1374187_57 | PHROG | phrog_4392 | NA | unknown function |
| UHGV-1374187_59 | KOfam | K00390 | cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] | NA |
| UHGV-1374187_59 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-1374187_59 | UniRef90 | UniRef90_UPI0009E1B041 | phosphoadenosine phosphosulfate reductase family protein | NA |
| UHGV-1374187_59 | eggNOG-mapper | 1408437.JNJN01000032_gene2312 | Phosphoadenosine phosphosulfate reductase | NA |
| UHGV-1374187_59 | PADLOC | BrxP_00001 | BrxP | BREX |
| UHGV-1374187_59 | Pfam | PF01507 | Phosphoadenosine phosphosulfate reductase family | PAPS_reduct |
| UHGV-1374187_59 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-1374187_59 | Structural annotation | PF01507, MF_00063, NF010369, COG0175 | NA | NA |
| UHGV-1374187_63 | PHROG | phrog_2245 | nucleoside triphosphate pyrophosphohydrolase | other |
| UHGV-1374187_63 | UniRef90 | UniRef90_A0A4U9RLZ8 | NA | NA |
| UHGV-1374187_63 | eggNOG-mapper | 428125.CLOLEP_01814 | COG NOG14118 non supervised orthologous group | NA |
| UHGV-1374187_63 | Structural annotation | PF12643, MF_01020, TIGR03188 | NA | NA |