| UHGV-1375396_1 | PHROG | phrog_12 | portal protein | head and packaging |
| UHGV-1375396_1 | UniRef90 | UniRef90_UPI000A82F727 | phage portal protein | NA |
| UHGV-1375396_1 | eggNOG-mapper | 1211817.CCAT010000008_gene940 | Phage portal protein | NA |
| UHGV-1375396_1 | COG | COG4695 | Phage portal protein BeeE | NA |
| UHGV-1375396_2 | PHROG | phrog_9 | terminase large subunit | head and packaging |
| UHGV-1375396_2 | UniRef90 | UniRef90_A0A1Q6MG31 | Terminase | NA |
| UHGV-1375396_2 | eggNOG-mapper | 610130.Closa_0741 | Phage Terminase | NA |
| UHGV-1375396_2 | Pfam | PF03354 | Terminase large subunit, ATPase domain | TerL_ATPase |
| UHGV-1375396_2 | Pfam | PF20441 | Terminase large subunit, endonuclease domain | TerL_nuclease |
| UHGV-1375396_2 | COG | COG4626 | Phage terminase-like protein, large subunit, contains N-terminal HTH domain | NA |
| UHGV-1375396_2 | Structural annotation | PF20441, PF03354, MF_04146, TIGR01547, COG4626 | NA | NA |
| UHGV-1375396_3 | PHROG | phrog_5110 | terminase small subunit | head and packaging |
| UHGV-1375396_3 | UniRef90 | UniRef90_A0A4U7JDP0 | P27 family phage terminase small subunit | NA |
| UHGV-1375396_3 | eggNOG-mapper | 86416.Clopa_0336 | NA | NA |
| UHGV-1375396_3 | Pfam | PF05119 | Phage terminase, small subunit | Terminase_4 |
| UHGV-1375396_3 | Structural annotation | PF05119, TIGR01558, COG3747 | NA | NA |
| UHGV-1375396_4 | PHROG | phrog_119 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1375396_4 | UniRef90 | UniRef90_A0A1Q6MG73 | HNH domain-containing protein | NA |
| UHGV-1375396_4 | eggNOG-mapper | 768710.DesyoDRAFT_1275 | HNH nucleases | NA |
| UHGV-1375396_4 | Pfam | PF01844 | HNH endonuclease | HNH |
| UHGV-1375396_4 | COG | COG1403 | 5-methylcytosine-specific restriction endonuclease McrA | NA |
| UHGV-1375396_5 | PHROG | phrog_11237 | NA | unknown function |
| UHGV-1375396_5 | eggNOG-mapper | 1235798.C817_04578 | NA | NA |
| UHGV-1375396_7 | Structural annotation | PF02452, NF010262, COG2337 | NA | NA |
| UHGV-1375396_12 | PHROG | phrog_2245 | nucleoside triphosphate pyrophosphohydrolase | other |
| UHGV-1375396_12 | UniRef90 | UniRef90_A0A373NRP8 | MazG domain-containing protein | NA |
| UHGV-1375396_12 | eggNOG-mapper | 706433.HMPREF9430_01279 | NA | NA |
| UHGV-1375396_12 | Pfam | PF03819 | MazG nucleotide pyrophosphohydrolase domain | MazG |
| UHGV-1375396_12 | Structural annotation | PF12643, MF_01020, TIGR03188 | NA | NA |
| UHGV-1375396_13 | PHROG | phrog_7566 | NA | unknown function |
| UHGV-1375396_13 | eggNOG-mapper | 411459.RUMOBE_00948 | NA | NA |
| UHGV-1375396_14 | eggNOG-mapper | 411468.CLOSCI_00555 | NA | NA |
| UHGV-1375396_15 | eggNOG-mapper | 411468.CLOSCI_00572 | NA | NA |
| UHGV-1375396_16 | Structural annotation | PF06257, TIGR00739, COG4466 | NA | NA |
| UHGV-1375396_18 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-1375396_18 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-1375396_18 | UniRef90 | UniRef90_A0A3R6PIU8 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1375396_18 | eggNOG-mapper | 1235800.C819_02255 | C-5 cytosine-specific DNA methylase | NA |
| UHGV-1375396_18 | PADLOC | MTase_II_00020 | Type II methyltransferase | RM |
| UHGV-1375396_18 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-1375396_18 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-1375396_18 | Structural annotation | PF00145, MF_00351, TIGR00675, COG0270 | NA | NA |
| UHGV-1375396_19 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-1375396_19 | UniRef90 | UniRef90_A0A2H4JC51 | Putative 3'-phosphoadenosine 5'-phosphosulfatesulfotransferase/FAD synthetase-related enzyme | NA |
| UHGV-1375396_19 | eggNOG-mapper | 411461.DORFOR_01142 | NA | NA |
| UHGV-1375396_19 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-1375396_19 | Structural annotation | PF01507, MF_00064, TIGR00434, COG0175 | NA | NA |
| UHGV-1375396_20 | KOfam | K03469 | rnhA, RNASEH1; ribonuclease HI [EC:3.1.26.4] | NA |
| UHGV-1375396_20 | PHROG | phrog_531 | Rnase H | DNA, RNA and nucleotide metabolism |
| UHGV-1375396_20 | UniRef90 | UniRef90_A0A1Q6MG39 | RNase H type-1 domain-containing protein | NA |
| UHGV-1375396_20 | eggNOG-mapper | 123214.PERMA_0423 | Endonuclease that specifically degrades the RNA of RNA- DNA hybrids | NA |
| UHGV-1375396_20 | Pfam | PF00075 | RNase H | RNase_H |
| UHGV-1375396_20 | COG | COG0328 | Ribonuclease HI | NA |
| UHGV-1375396_21 | PHROG | phrog_3584 | replication initiation protein | DNA, RNA and nucleotide metabolism |
| UHGV-1375396_21 | eggNOG-mapper | 411459.RUMOBE_00953 | NA | NA |
| UHGV-1375396_21 | Structural annotation | PF01446 | NA | NA |
| UHGV-1375396_22 | PHROG | phrog_20014 | NA | unknown function |
| UHGV-1375396_22 | eggNOG-mapper | 1235798.C817_02590 | NA | NA |
| UHGV-1375396_23 | Pfam | PF09874 | NA | DUF2101 |
| UHGV-1375396_24 | PHROG | phrog_6058 | NA | unknown function |
| UHGV-1375396_24 | UniRef90 | UniRef90_A0A7X9GS36 | Helix-turn-helix domain-containing protein | NA |
| UHGV-1375396_24 | eggNOG-mapper | 742823.HMPREF9465_00186 | NA | NA |
| UHGV-1375396_24 | Structural annotation | PF12728, NF033787 | NA | NA |
| UHGV-1375396_25 | KOfam | K03427 | hsdM; type I restriction enzyme M protein [EC:2.1.1.72] | NA |
| UHGV-1375396_25 | PHROG | phrog_6380 | DNA methyltransferase | other |
| UHGV-1375396_25 | UniRef90 | UniRef90_UPI0019570FFD | N-6 DNA methylase | NA |
| UHGV-1375396_25 | eggNOG-mapper | 1401067.HMPREF0872_03510 | type I restriction-modification system | NA |
| UHGV-1375396_25 | PADLOC | MTase_I_00005 | Type I methyltransferase | RM |
| UHGV-1375396_25 | Pfam | PF02384 | N-6 DNA Methylase | N6_Mtase |
| UHGV-1375396_25 | COG | COG0286 | Type I restriction-modification system, DNA methylase subunit | NA |
| UHGV-1375396_26 | Structural annotation | PF19005 | NA | NA |
| UHGV-1375396_28 | PHROG | phrog_3886 | NA | unknown function |
| UHGV-1375396_28 | eggNOG-mapper | 742740.HMPREF9474_02292 | NA | NA |
| UHGV-1375396_29 | KOfam | K03744 | lemA; LemA protein | NA |
| UHGV-1375396_29 | PHROG | phrog_1383 | virion structural protein | head and packaging |
| UHGV-1375396_29 | UniRef90 | UniRef90_A0A1Q6MG17 | LemA family protein | NA |
| UHGV-1375396_29 | eggNOG-mapper | 742735.HMPREF9467_00879 | LemA family | NA |
| UHGV-1375396_29 | Pfam | PF04011 | LemA family | LemA |
| UHGV-1375396_29 | COG | COG1704 | Magnetosome formation protein MamQ, lipoprotein antigen LemA family | NA |
| UHGV-1375396_29 | Structural annotation | PF04011, NF040966, COG1704 | NA | NA |
| UHGV-1375396_33 | KOfam | K07729 | K07729; putative transcriptional regulator | NA |
| UHGV-1375396_33 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-1375396_33 | UniRef90 | UniRef90_R5WNF4 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-1375396_33 | eggNOG-mapper | 268407.PWYN_23755 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-1375396_33 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1375396_33 | Structural annotation | PF01381, NF041951, COG1476 | NA | NA |
| UHGV-1375396_34 | KOfam | K01356 | lexA; repressor LexA [EC:3.4.21.88] | NA |
| UHGV-1375396_34 | PHROG | phrog_4 | transcriptional repressor | transcription regulation |
| UHGV-1375396_34 | UniRef90 | UniRef90_R5VT81 | LexA repressor | NA |
| UHGV-1375396_34 | eggNOG-mapper | 478749.BRYFOR_07570 | Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair | NA |
| UHGV-1375396_34 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1375396_34 | Pfam | PF00717 | Peptidase S24-like | Peptidase_S24 |
| UHGV-1375396_34 | COG | COG1974 | SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) | NA |
| UHGV-1375396_34 | Structural annotation | PF01381, PF00717, MF_00015, NF041951, COG1396 | NA | NA |
| UHGV-1375396_35 | PHROG | phrog_8043 | NA | unknown function |
| UHGV-1375396_35 | UniRef90 | UniRef90_A0A1Q6MG25 | HIRAN domain-containing protein | NA |
| UHGV-1375396_35 | eggNOG-mapper | 1336234.JAGN01000004_gene559 | HIRAN domain | NA |
| UHGV-1375396_35 | Pfam | PF08797 | HIRAN domain | HIRAN |
| UHGV-1375396_37 | KOfam | K07339 | hicA; mRNA interferase HicA [EC:3.1.-.-] | NA |
| UHGV-1375396_37 | PHROG | phrog_353 | toxin | moron, auxiliary metabolic gene and host takeover |
| UHGV-1375396_37 | UniRef90 | UniRef90_A0A3R6X664 | Addiction module toxin, HicA family | NA |
| UHGV-1375396_37 | eggNOG-mapper | 1408311.JNJM01000002_gene1308 | HicA toxin of bacterial toxin-antitoxin, | NA |
| UHGV-1375396_37 | Pfam | PF07927 | HicA toxin of bacterial toxin-antitoxin, | HicA_toxin |
| UHGV-1375396_37 | COG | COG1724 | Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family | NA |
| UHGV-1375396_37 | Structural annotation | PF07927, COG1724 | NA | NA |
| UHGV-1375396_38 | KOfam | K18843 | hicB; antitoxin HicB | NA |
| UHGV-1375396_38 | PHROG | phrog_497 | toxin-antitoxin system HicB-like | moron, auxiliary metabolic gene and host takeover |
| UHGV-1375396_38 | UniRef90 | UniRef90_A0A1Q6MG32 | HicB family protein | NA |
| UHGV-1375396_38 | eggNOG-mapper | 397287.C807_02051 | HicB_like antitoxin of bacterial toxin-antitoxin system | NA |
| UHGV-1375396_38 | Pfam | PF15919 | HicB_like antitoxin of bacterial toxin-antitoxin system | HicB_lk_antitox |
| UHGV-1375396_38 | COG | COG1598 | Antitoxin component HicB of the HicAB toxin-antitoxin system | NA |
| UHGV-1375396_38 | Structural annotation | PF15919, COG1598 | NA | NA |
| UHGV-1375396_39 | KOfam | K14059 | int; integrase | NA |
| UHGV-1375396_39 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-1375396_39 | UniRef90 | UniRef90_A0A1Q6MGA4 | Site-specific integrase | NA |
| UHGV-1375396_39 | eggNOG-mapper | 742741.HMPREF9475_00397 | Phage integrase family | NA |
| UHGV-1375396_39 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-1375396_39 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-1375396_39 | Structural annotation | PF00589, MF_01808, NF007246, COG4974 | NA | NA |
| UHGV-1375396_40 | PHROG | phrog_13890 | NA | unknown function |
| UHGV-1375396_41 | KOfam | K07273 | acm; lysozyme | NA |
| UHGV-1375396_41 | PHROG | phrog_291 | endolysin | lysis |
| UHGV-1375396_41 | UniRef90 | UniRef90_A0A173W541 | Lysozyme M1 | NA |
| UHGV-1375396_41 | eggNOG-mapper | 411474.COPEUT_02639 | hydrolase, family 25 | NA |
| UHGV-1375396_41 | Pfam | PF01183 | Glycosyl hydrolases family 25 | Glyco_hydro_25 |
| UHGV-1375396_41 | Pfam | PF08230 | CW_7 repeat | CW_7 |
| UHGV-1375396_41 | COG | COG3023 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD | NA |
| UHGV-1375396_41 | Structural annotation | PF01183, PF01476, TIGR02899, COG3757, COG1388 | NA | NA |
| UHGV-1375396_42 | PHROG | phrog_18218 | NA | unknown function |
| UHGV-1375396_42 | UniRef90 | UniRef90_A0A374AVT4 | Ribonuclease | NA |
| UHGV-1375396_42 | eggNOG-mapper | 411474.COPEUT_02638 | NA | NA |
| UHGV-1375396_42 | Structural annotation | PF06946 | NA | NA |
| UHGV-1375396_43 | UniRef90 | UniRef90_A0A3A6JFT7 | Branched-chain amino acid ABC transporter permease | NA |
| UHGV-1375396_43 | eggNOG-mapper | 742765.HMPREF9457_03364 | NA | NA |
| UHGV-1375396_44 | Structural annotation | PF12571, MF_00791, NF003967, COG2967 | NA | NA |
| UHGV-1375396_45 | eggNOG-mapper | 657322.FPR_22010 | NA | NA |
| UHGV-1375396_46 | PHROG | phrog_9994 | NA | unknown function |
| UHGV-1375396_46 | UniRef90 | UniRef90_A0A087E4D0 | Phage-related putative tail protein | NA |
| UHGV-1375396_46 | eggNOG-mapper | 658655.HMPREF0988_02549 | NA | NA |
| UHGV-1375396_46 | Structural annotation | PF20747 | NA | NA |
| UHGV-1375396_47 | PHROG | phrog_538 | minor tail protein | tail |
| UHGV-1375396_47 | UniRef90 | UniRef90_W0FH81 | Phage head fiber protein | NA |
| UHGV-1375396_47 | eggNOG-mapper | 1256908.HMPREF0373_00466 | NA | NA |
| UHGV-1375396_47 | Pfam | PF14594 | Siphovirus ReqiPepy6 Gp37-like protein | Sipho_Gp37 |
| UHGV-1375396_47 | Structural annotation | PF14594, TIGR01665, COG4379 | NA | NA |
| UHGV-1375396_48 | PHROG | phrog_33 | distal tail protein Dit | tail |
| UHGV-1375396_48 | UniRef90 | UniRef90_UPI0015709E93 | phage tail protein | NA |
| UHGV-1375396_48 | eggNOG-mapper | 411468.CLOSCI_00277 | NA | NA |
| UHGV-1375396_48 | Structural annotation | PF16774, TIGR01633, COG4722 | NA | NA |
| UHGV-1375396_49 | PHROG | phrog_1272 | tail length tape measure protein | tail |
| UHGV-1375396_49 | UniRef90 | UniRef90_A0A1Q6MG21 | PhageMin_Tail domain-containing protein | NA |
| UHGV-1375396_49 | eggNOG-mapper | 999413.HMPREF1094_02001 | Phage-related minor tail protein | NA |
| UHGV-1375396_49 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-1375396_49 | COG | COG5280 | Phage-related minor tail protein | NA |
| UHGV-1375396_49 | Structural annotation | PF10145, TIGR01760, COG5280 | NA | NA |
| UHGV-1375396_52 | UniRef90 | UniRef90_A0A374TPV8 | Phage tail protein | NA |
| UHGV-1375396_52 | eggNOG-mapper | 1384484.AEQU_1175 | NA | NA |
| UHGV-1375396_52 | Structural annotation | PF04630, TIGR01603, COG5437 | NA | NA |
| UHGV-1375396_53 | PHROG | phrog_5509 | neck protein | connector |
| UHGV-1375396_53 | UniRef90 | UniRef90_W0FMR6 | Gp9 protein | NA |
| UHGV-1375396_53 | eggNOG-mapper | 1347392.CCEZ01000045_gene11 | NA | NA |
| UHGV-1375396_53 | Structural annotation | TIGR01725 | NA | NA |
| UHGV-1375396_54 | Structural annotation | PF05657, COG3167 | NA | NA |
| UHGV-1375396_55 | PHROG | phrog_5635 | head-tail adaptor | connector |
| UHGV-1375396_55 | UniRef90 | UniRef90_UPI0011070497 | phage head closure protein | NA |
| UHGV-1375396_55 | Structural annotation | PF05521, TIGR01563, COG5614 | NA | NA |
| UHGV-1375396_56 | PHROG | phrog_749 | NA | unknown function |
| UHGV-1375396_56 | UniRef90 | UniRef90_W0FM58 | Gp6 protein | NA |
| UHGV-1375396_56 | eggNOG-mapper | 349161.Dred_2603 | NA | NA |
| UHGV-1375396_57 | PHROG | phrog_10 | major head protein | head and packaging |
| UHGV-1375396_57 | UniRef90 | UniRef90_W0FH89 | MAjor capsid protein a | NA |
| UHGV-1375396_57 | eggNOG-mapper | 1384484.AEQU_1180 | Phage capsid family | NA |
| UHGV-1375396_57 | Pfam | PF05065 | Phage capsid family | Phage_capsid |
| UHGV-1375396_57 | NCBIFam | TIGR01554.2 | phage major capsid protein | NA |
| UHGV-1375396_57 | COG | COG4653 | Predicted phage phi-C31 gp36 major capsid-like protein | NA |
| UHGV-1375396_57 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-1375396_58 | KOfam | K01358 | clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] | NA |
| UHGV-1375396_58 | PHROG | phrog_94 | head maturation protease | head and packaging |
| UHGV-1375396_58 | UniRef90 | UniRef90_A0A1Q6MG19 | ATP-dependent Clp protease proteolytic subunit | NA |
| UHGV-1375396_58 | eggNOG-mapper | 1232452.BAIB02000007_gene1626 | Belongs to the peptidase S14 family | NA |
| UHGV-1375396_58 | Pfam | PF00574 | Clp protease | CLP_protease |
| UHGV-1375396_58 | COG | COG0740 | ATP-dependent protease ClpP, protease subunit | NA |
| UHGV-1375396_58 | Structural annotation | PF00574, MF_00444, NF011090, COG0740 | NA | NA |
| UHGV-1375396_59 | PHROG | phrog_12 | portal protein | head and packaging |
| UHGV-1375396_59 | UniRef90 | UniRef90_A0A1Q6MFZ4 | Phage portal protein | NA |
| UHGV-1375396_59 | eggNOG-mapper | 1121866.AUGK01000006_gene878 | Phage portal protein | NA |
| UHGV-1375396_59 | Pfam | PF04860 | Phage portal protein | Phage_portal |
| UHGV-1375396_59 | COG | COG4695 | Phage portal protein BeeE | NA |