| UHGV-1859586_1 | eggNOG-mapper | 748224.HMPREF9436_00405 | domain, Protein | NA |
| UHGV-1859586_1 | COG | COG5492 | NA | NA |
| UHGV-1859586_2 | PHROG | phrog_18725 | NA | unknown function |
| UHGV-1859586_2 | eggNOG-mapper | 1226322.HMPREF1545_00062 | NA | NA |
| UHGV-1859586_3 | PHROG | phrog_13879 | NA | unknown function |
| UHGV-1859586_3 | eggNOG-mapper | 1122919.KB905559_gene1344 | NA | NA |
| UHGV-1859586_3 | Pfam | PF19789 | NA | DUF6273 |
| UHGV-1859586_3 | Structural annotation | PF14594, PF19789, PF03256, PF09134, NF033848, COG3500, COG5156 | NA | NA |
| UHGV-1859586_4 | PHROG | phrog_1194 | NA | unknown function |
| UHGV-1859586_4 | eggNOG-mapper | 665956.HMPREF1032_03629 | NA | NA |
| UHGV-1859586_4 | Pfam | PF20458 | NA | DUF6711 |
| UHGV-1859586_4 | Structural annotation | PF20458, TIGR02126, COG3499 | NA | NA |
| UHGV-1859586_5 | PHROG | phrog_1535 | tail length tape measure protein | tail |
| UHGV-1859586_5 | eggNOG-mapper | 1121866.AUGK01000003_gene1437 | phage tail tape measure protein | NA |
| UHGV-1859586_5 | COG | COG1280 | Threonine/homoserine/homoserine lactone efflux protein | NA |
| UHGV-1859586_6 | eggNOG-mapper | 1121333.JMLH01000047_gene1011 | NA | NA |
| UHGV-1859586_7 | UniRef90 | UniRef90_A0A847YX95 | NA | NA |
| UHGV-1859586_7 | eggNOG-mapper | 1123263.AUKY01000015_gene1618 | NA | NA |
| UHGV-1859586_7 | Pfam | PF16478 | NA | DUF5055 |
| UHGV-1859586_7 | Structural annotation | PF16478 | NA | NA |
| UHGV-1859586_8 | PHROG | phrog_158 | major tail protein | tail |
| UHGV-1859586_8 | UniRef90 | UniRef90_UPI001D087591 | phage tail protein | NA |
| UHGV-1859586_8 | eggNOG-mapper | 1449343.JQLQ01000002_gene1514 | Phage tail tube protein, TTP | NA |
| UHGV-1859586_8 | Structural annotation | PF16463, TIGR02241, COG5437 | NA | NA |
| UHGV-1859586_9 | Structural annotation | PF06141, TIGR02367, COG3167 | NA | NA |
| UHGV-1859586_11 | Structural annotation | PF19586, TIGR01563, COG5614 | NA | NA |
| UHGV-1859586_12 | UniRef90 | UniRef90_R6N215 | Phage QLRG family putative DNA packaging | NA |
| UHGV-1859586_12 | Structural annotation | TIGR01560 | NA | NA |
| UHGV-1859586_13 | PHROG | phrog_29 | major head protein | head and packaging |
| UHGV-1859586_13 | UniRef90 | UniRef90_A0A2Z4QBB4 | Major capsid protein E | NA |
| UHGV-1859586_13 | eggNOG-mapper | 476272.RUMHYD_01946 | Phage major capsid protein E | NA |
| UHGV-1859586_13 | Pfam | PF03864 | Phage major capsid protein E | Phage_cap_E |
| UHGV-1859586_13 | Structural annotation | PF03864, MF_04133, NF041162, COG4653 | NA | NA |
| UHGV-1859586_16 | UniRef90 | UniRef90_UPI001F3ECC8A | NA | NA |
| UHGV-1859586_16 | eggNOG-mapper | 397290.C810_05229 | NA | NA |
| UHGV-1859586_16 | Structural annotation | PF14359, NF040588, COG3613 | NA | NA |
| UHGV-1859586_17 | PHROG | phrog_64 | portal protein | head and packaging |
| UHGV-1859586_17 | UniRef90 | UniRef90_A0A371ILT4 | Phage portal protein | NA |
| UHGV-1859586_17 | eggNOG-mapper | 1121866.AUGK01000003_gene1429 | Phage portal protein, SPP1 Gp6-like | NA |
| UHGV-1859586_17 | Pfam | PF05133 | Phage portal protein, SPP1 Gp6-like | Phage_prot_Gp6 |
| UHGV-1859586_17 | Structural annotation | PF05133, MF_04120, TIGR01538, COG5511 | NA | NA |
| UHGV-1859586_19 | PHROG | phrog_38 | terminase large subunit | head and packaging |
| UHGV-1859586_19 | UniRef90 | UniRef90_UPI000419A6BC | phage terminase large subunit | NA |
| UHGV-1859586_19 | eggNOG-mapper | 1121866.AUGK01000003_gene1428 | chromosome segregation | NA |
| UHGV-1859586_19 | COG | COG5410 | NA | NA |
| UHGV-1859586_19 | Structural annotation | PF17289, PF02562, MF_04147, NF033889, COG5362, COG5410 | NA | NA |
| UHGV-1859586_23 | KOfam | K06400 | spoIVCA; site-specific DNA recombinase | NA |
| UHGV-1859586_23 | PHROG | phrog_95 | integrase | integration and excision |
| UHGV-1859586_23 | UniRef90 | UniRef90_A0A3D4G6V8 | Resolvase | NA |
| UHGV-1859586_23 | eggNOG-mapper | 697329.Rumal_3466 | resolvase | NA |
| UHGV-1859586_23 | Pfam | PF00239 | Resolvase, N terminal domain | Resolvase |
| UHGV-1859586_23 | Pfam | PF07508 | Recombinase | Recombinase |
| UHGV-1859586_23 | COG | COG1961 | Site-specific DNA recombinase SpoIVCA/DNA invertase PinE | NA |
| UHGV-1859586_23 | Structural annotation | PF00239, PF07508, NF041201, COG1961 | NA | NA |
| UHGV-1859586_25 | Structural annotation | PF19807, NF041793, COG4877 | NA | NA |
| UHGV-1859586_26 | KOfam | K07741 | antB; anti-repressor protein | NA |
| UHGV-1859586_26 | PHROG | phrog_130 | anti-repressor Ant | transcription regulation |
| UHGV-1859586_26 | UniRef90 | UniRef90_A0A8D4D1X2 | Bro-N domain-containing protein | NA |
| UHGV-1859586_26 | eggNOG-mapper | 1289596.M1PKL6_9CAUD | BRO family, N-terminal domain | NA |
| UHGV-1859586_26 | Pfam | PF02498 | BRO family, N-terminal domain | Bro-N |
| UHGV-1859586_26 | Pfam | PF03374 | Phage antirepressor protein KilAC domain | ANT |
| UHGV-1859586_26 | Structural annotation | PF02498, PF03374, TIGR02681, COG3645, COG3561 | NA | NA |
| UHGV-1859586_27 | Structural annotation | PF09624, PF14263, MF_00791, NF038353, TIGR02588, COG4885 | NA | NA |
| UHGV-1859586_32 | PHROG | phrog_434 | RecE-like recombination exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1859586_32 | eggNOG-mapper | 742738.HMPREF9460_00717 | YqaJ viral recombinase family | NA |
| UHGV-1859586_32 | COG | COG5377 | Phage-related protein, predicted endonuclease | NA |
| UHGV-1859586_34 | PHROG | phrog_1709 | NA | unknown function |
| UHGV-1859586_34 | eggNOG-mapper | 500632.CLONEX_01053 | NA | NA |
| UHGV-1859586_35 | PHROG | phrog_419 | NA | unknown function |
| UHGV-1859586_35 | UniRef90 | UniRef90_A6MAI4 | Gp119 | NA |
| UHGV-1859586_35 | eggNOG-mapper | 768486.EHR_02665 | NA | NA |
| UHGV-1859586_35 | Structural annotation | PF14083 | NA | NA |
| UHGV-1859586_36 | KOfam | K02314 | dnaB; replicative DNA helicase [EC:5.6.2.3] | NA |
| UHGV-1859586_36 | PHROG | phrog_19 | DnaB-like replicative helicase | DNA, RNA and nucleotide metabolism |
| UHGV-1859586_36 | UniRef90 | UniRef90_UPI001CBC4B63 | AAA family ATPase | NA |
| UHGV-1859586_36 | eggNOG-mapper | 1203606.HMPREF1526_01325 | Participates in initiation and elongation during chromosome replication | NA |
| UHGV-1859586_36 | Pfam | PF03796 | DnaB-like helicase C terminal domain | DnaB_C |
| UHGV-1859586_36 | COG | COG0305 | Replicative DNA helicase | NA |
| UHGV-1859586_36 | Structural annotation | PF03796, PF00772, MF_04155, TIGR00665, COG0305 | NA | NA |
| UHGV-1859586_37 | PHROG | phrog_15768 | NA | unknown function |
| UHGV-1859586_37 | UniRef90 | UniRef90_A0A6N7WKT0 | NA | NA |
| UHGV-1859586_37 | eggNOG-mapper | 1189620.AJXL01000045_gene1040 | NA | NA |
| UHGV-1859586_37 | Pfam | PF19808 | NA | DUF6291 |
| UHGV-1859586_37 | Structural annotation | PF19808 | NA | NA |
| UHGV-1859586_38 | PHROG | phrog_599 | Lar-like restriction alleviation protein | moron, auxiliary metabolic gene and host takeover |
| UHGV-1859586_38 | Pfam | PF14354 | Restriction alleviation protein Lar | Lar_restr_allev |
| UHGV-1859586_38 | NCBIFam | TIGR03655.1 | Lar family restriction alleviation protein | NA |
| UHGV-1859586_38 | dbAPIS | APIS033 | Lar is functionally similar to RaI, is able to alleviate restriction and enhance modification by EcoKI. And the nucleotide sequences of their genes share 47% identity, indicating a common origin. | NA |
| UHGV-1859586_38 | Structural annotation | NF007260 | NA | NA |
| UHGV-1859586_42 | Structural annotation | NF041588 | NA | NA |
| UHGV-1859586_44 | KOfam | K22300 | dicA; HTH-type transcriptional regulator, cell division transcriptional repressor | NA |
| UHGV-1859586_44 | PHROG | phrog_11947 | NA | unknown function |
| UHGV-1859586_44 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1859586_44 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1859586_44 | Structural annotation | PF01381, MF_00535, TIGR03070, COG1476 | NA | NA |
| UHGV-1859586_48 | PHROG | phrog_14697 | NA | unknown function |
| UHGV-1859586_48 | eggNOG-mapper | 665950.HMPREF1025_01969 | COG NOG28949 non supervised orthologous group | NA |
| UHGV-1859586_48 | COG | COG0241 | Histidinol phosphatase/D-glycero-mannoheptose bisphosphatephosphatase, HAD superfamily | NA |
| UHGV-1859586_49 | UniRef90 | UniRef90_UPI0012DD33A2 | restriction endonuclease subunit M | NA |
| UHGV-1859586_49 | eggNOG-mapper | 1121333.JMLH01000037_gene2007 | restriction endonuclease | NA |
| UHGV-1859586_49 | PADLOC | MTase_II_00176 | Type II methyltransferase | RM |
| UHGV-1859586_49 | COG | COG1002 | Type II restriction/modification system, endonuclease and methylase domains | NA |
| UHGV-1859586_50 | Structural annotation | PF16677 | NA | NA |
| UHGV-1859586_51 | UniRef90 | UniRef90_UPI000D6522D3 | NA | NA |
| UHGV-1859586_51 | Pfam | PF04448 | NA | DUF551 |
| UHGV-1859586_51 | Structural annotation | PF04448, NF041588 | NA | NA |
| UHGV-1859586_53 | KOfam | K00390 | cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] | NA |
| UHGV-1859586_53 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-1859586_53 | UniRef90 | UniRef90_A0A1Y4LU27 | Adenylyl-sulfate reductase | NA |
| UHGV-1859586_53 | eggNOG-mapper | 1408437.JNJN01000032_gene2312 | Phosphoadenosine phosphosulfate reductase | NA |
| UHGV-1859586_53 | PADLOC | BrxP_00001 | BrxP | BREX |
| UHGV-1859586_53 | Pfam | PF01507 | Phosphoadenosine phosphosulfate reductase family | PAPS_reduct |
| UHGV-1859586_53 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-1859586_53 | Structural annotation | PF01507, MF_00063, NF010369, COG0175 | NA | NA |
| UHGV-1859586_56 | Pfam | PF03819 | MazG nucleotide pyrophosphohydrolase domain | MazG |
| UHGV-1859586_56 | Structural annotation | PF11998, COG5420 | NA | NA |
| UHGV-1859586_58 | PHROG | phrog_843 | Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-1859586_58 | UniRef90 | UniRef90_UPI001159D907 | Holliday junction resolvase RecU | NA |
| UHGV-1859586_58 | eggNOG-mapper | 929506.CbC4_1203 | Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation | NA |
| UHGV-1859586_58 | Structural annotation | PF03838, MF_00130, NF002581, COG3331 | NA | NA |
| UHGV-1859586_61 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-1859586_61 | PHROG | phrog_16427 | DNA methyltransferase | other |
| UHGV-1859586_61 | UniRef90 | UniRef90_D4K5C7 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1859586_61 | eggNOG-mapper | 657322.FPR_26610 | DNA (cytosine-5-)-methyltransferase activity | NA |
| UHGV-1859586_61 | PADLOC | oMTase_00004 | orphan methyltransferase | RM |
| UHGV-1859586_61 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-1859586_61 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-1859586_63 | PHROG | phrog_18107 | NA | unknown function |
| UHGV-1859586_63 | UniRef90 | UniRef90_UPI00058F46CC | NA | NA |
| UHGV-1859586_63 | eggNOG-mapper | 903814.ELI_1274 | NA | NA |
| UHGV-1859586_63 | Structural annotation | PF05037 | NA | NA |
| UHGV-1859586_64 | PHROG | phrog_2872 | Sak4-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-1859586_64 | UniRef90 | UniRef90_A0A8J6JIF1 | AAA family ATPase | NA |
| UHGV-1859586_64 | eggNOG-mapper | 754027.HMPREF9554_00709 | NA | NA |
| UHGV-1859586_64 | Pfam | PF13479 | AAA domain | AAA_24 |
| UHGV-1859586_64 | Structural annotation | PF13479, MF_00350, TIGR01618, COG0468 | NA | NA |
| UHGV-1859586_65 | Pfam | PF13451 | Probable zinc-ribbon domain | zf-trcl |
| UHGV-1859586_65 | COG | COG1278 | Cold shock protein, CspA family | NA |
| UHGV-1859586_65 | Structural annotation | PF13451 | NA | NA |
| UHGV-1859586_67 | KOfam | K07738 | nrdR; transcriptional repressor NrdR | NA |
| UHGV-1859586_67 | Pfam | PF01096 | Transcription factor S-II (TFIIS) | TFIIS_C |
| UHGV-1859586_67 | COG | COG1327 | Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains | NA |
| UHGV-1859586_67 | Structural annotation | PF04606, NF007241 | NA | NA |
| UHGV-1859586_68 | Structural annotation | PF14143 | NA | NA |
| UHGV-1859586_69 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-1859586_69 | Structural annotation | PF13443, TIGR02684, COG1476 | NA | NA |
| UHGV-1859586_71 | Structural annotation | TIGR03826 | NA | NA |
| UHGV-1859586_73 | Structural annotation | PF10922 | NA | NA |
| UHGV-1859586_74 | UniRef90 | UniRef90_UPI001956DCC9 | helix-turn-helix transcriptional regulator | NA |
| UHGV-1859586_74 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1859586_74 | Structural annotation | PF13560, NF041951, COG1396 | NA | NA |
| UHGV-1859586_75 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-1859586_75 | UniRef90 | UniRef90_UPI001D05D211 | helix-turn-helix transcriptional regulator | NA |
| UHGV-1859586_75 | eggNOG-mapper | 693746.OBV_43290 | addiction module antidote protein HigA | NA |
| UHGV-1859586_75 | COG | COG3093 | Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain | NA |
| UHGV-1859586_75 | Structural annotation | PF01381, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-1859586_77 | Pfam | PF08951 | Enterocin A Immunity | EntA_Immun |
| UHGV-1859586_78 | UniRef90 | UniRef90_A0A2A7AM70 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-1859586_78 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1859586_78 | Structural annotation | PF13560, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-1859586_80 | PHROG | phrog_4402 | replication initiation protein | DNA, RNA and nucleotide metabolism |
| UHGV-1859586_80 | UniRef90 | UniRef90_A0A0H5Q331 | Rep_3 domain-containing protein | NA |
| UHGV-1859586_80 | eggNOG-mapper | 999413.HMPREF1094_04438 | Initiator Replication protein | NA |
| UHGV-1859586_80 | Pfam | PF01051 | Initiator Replication protein, WH1 | Rep3_N |
| UHGV-1859586_80 | Pfam | PF21205 | Initiator Rep protein, WH2 | Rep3_C |
| UHGV-1859586_80 | COG | COG5527 | Protein involved in initiation of plasmid replication | NA |
| UHGV-1859586_80 | Structural annotation | PF01051, PF21205, NF010305, COG5527 | NA | NA |
| UHGV-1859586_81 | KOfam | K03496 | parA, soj; chromosome partitioning protein | NA |
| UHGV-1859586_81 | PHROG | phrog_164 | ParA-like partition protein | DNA, RNA and nucleotide metabolism |
| UHGV-1859586_81 | UniRef90 | UniRef90_A0A1C6BS15 | Sporulation initiation inhibitor protein soj | NA |
| UHGV-1859586_81 | eggNOG-mapper | 1392502.JNIO01000004_gene6 | Cellulose biosynthesis protein BcsQ | NA |
| UHGV-1859586_81 | Pfam | PF13614 | AAA domain | AAA_31 |
| UHGV-1859586_81 | COG | COG1192 | ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ | NA |
| UHGV-1859586_81 | Structural annotation | PF13614, MF_00533, NF010443, COG1192 | NA | NA |
| UHGV-1859586_82 | UniRef90 | UniRef90_UPI001F533D4C | NA | NA |
| UHGV-1859586_82 | Pfam | PF04448 | NA | DUF551 |
| UHGV-1859586_83 | Structural annotation | PF07878 | NA | NA |
| UHGV-1859586_84 | PHROG | phrog_10980 | NA | unknown function |
| UHGV-1859586_84 | UniRef90 | UniRef90_G3MA20 | Gp279 | NA |
| UHGV-1859586_85 | KOfam | K13525 | VCP, CDC48; transitional endoplasmic reticulum ATPase | NA |
| UHGV-1859586_85 | PHROG | phrog_3757 | NA | unknown function |
| UHGV-1859586_85 | UniRef90 | UniRef90_A0A4Z0Y6M2 | ATP-dependent zinc metalloprotease FtsH 3 | NA |
| UHGV-1859586_85 | eggNOG-mapper | 768710.DesyoDRAFT_1087 | ATPase family associated with various cellular activities (AAA) | NA |
| UHGV-1859586_85 | PADLOC | IetA_00002 | NA | ietAS |
| UHGV-1859586_85 | Pfam | PF00004 | ATPase family associated with various cellular activities (AAA) | AAA |
| UHGV-1859586_85 | COG | COG0464 | AAA+-type ATPase, SpoVK/Ycf46/Vps4 family | NA |
| UHGV-1859586_85 | Structural annotation | PF00004, MF_00553, TIGR01242, COG1222 | NA | NA |
| UHGV-1859586_86 | Structural annotation | NF010188 | NA | NA |
| UHGV-1859586_87 | PHROG | phrog_7070 | NA | unknown function |
| UHGV-1859586_87 | eggNOG-mapper | 1195072.M4HPW0_9CAUD | NA | NA |
| UHGV-1859586_88 | eggNOG-mapper | 1408437.JNJN01000043_gene801 | NA | NA |
| UHGV-1859586_89 | eggNOG-mapper | 1408437.JNJN01000043_gene802 | NA | NA |
| UHGV-1859586_90 | PHROG | phrog_16490 | NA | unknown function |
| UHGV-1859586_90 | eggNOG-mapper | 1408437.JNJN01000043_gene803 | NA | NA |
| UHGV-1859586_94 | PHROG | phrog_15303 | NA | unknown function |
| UHGV-1859586_94 | Pfam | PF09682 | Bacteriophage holin of superfamily 6 (Holin_LLH) | Phage_holin_6_1 |
| UHGV-1859586_96 | KOfam | K07273 | acm; lysozyme | NA |
| UHGV-1859586_96 | PHROG | phrog_291 | endolysin | lysis |
| UHGV-1859586_96 | UniRef90 | UniRef90_A0A564U0D3 | Autolytic lysozyme | NA |
| UHGV-1859586_96 | eggNOG-mapper | 718252.FP2_04890 | hydrolase, family 25 | NA |
| UHGV-1859586_96 | Pfam | PF01183 | Glycosyl hydrolases family 25 | Glyco_hydro_25 |
| UHGV-1859586_96 | COG | COG3757 | Lyzozyme M1 (1,4-beta-N-acetylmuramidase), GH25 family | NA |
| UHGV-1859586_96 | Structural annotation | PF01183, NF007404, COG3757 | NA | NA |
| UHGV-1859586_97 | PHROG | phrog_1382 | NA | unknown function |
| UHGV-1859586_97 | eggNOG-mapper | 33035.JPJF01000043_gene998 | NA | NA |
| UHGV-1859586_99 | eggNOG-mapper | 748224.HMPREF9436_00702 | COG NOG18825 non supervised orthologous group | NA |