| UHGV-0004559_1 | KOfam | K14059 | int; integrase | NA |
| UHGV-0004559_1 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-0004559_1 | UniRef90 | UniRef90_A0A3A6JBV3 | Site-specific integrase | NA |
| UHGV-0004559_1 | eggNOG-mapper | 1280698.AUJS01000007_gene999 | Phage integrase family | NA |
| UHGV-0004559_1 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-0004559_1 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-0004559_1 | Structural annotation | PF00589, PF14659, MF_02055, TIGR02224, COG4974 | NA | NA |
| UHGV-0004559_2 | PHROG | phrog_13890 | NA | unknown function |
| UHGV-0004559_2 | UniRef90 | UniRef90_A0A7X5I8W7 | Arc family DNA-binding protein | NA |
| UHGV-0004559_2 | eggNOG-mapper | 1378168.N510_00539 | NA | NA |
| UHGV-0004559_2 | Structural annotation | PF10723, NF010256, COG4710 | NA | NA |
| UHGV-0004559_3 | KOfam | K07171 | mazF, ndoA, chpA; mRNA interferase MazF [EC:3.1.-.-] | NA |
| UHGV-0004559_3 | PHROG | phrog_1412 | antitoxin mazE-like | moron, auxiliary metabolic gene and host takeover |
| UHGV-0004559_3 | UniRef90 | UniRef90_A0A415LA35 | Type II toxin-antitoxin system PemK/MazF family toxin | NA |
| UHGV-0004559_3 | eggNOG-mapper | 1235792.C808_05257 | Toxic component of a toxin-antitoxin (TA) module | NA |
| UHGV-0004559_3 | Pfam | PF02452 | PemK-like, MazF-like toxin of type II toxin-antitoxin system | PemK_toxin |
| UHGV-0004559_3 | COG | COG2337 | mRNA-degrading endonuclease MazF, toxin component of the MazEF toxin-antitoxin module | NA |
| UHGV-0004559_3 | Structural annotation | PF02452, NF007386, COG2337 | NA | NA |
| UHGV-0004559_5 | KOfam | K01356 | lexA; repressor LexA [EC:3.4.21.88] | NA |
| UHGV-0004559_5 | PHROG | phrog_4 | transcriptional repressor | transcription regulation |
| UHGV-0004559_5 | UniRef90 | UniRef90_A0A822LS29 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-0004559_5 | eggNOG-mapper | 706434.HMPREF9429_00405 | Peptidase S24-like | NA |
| UHGV-0004559_5 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0004559_5 | Pfam | PF00717 | Peptidase S24-like | Peptidase_S24 |
| UHGV-0004559_5 | COG | COG1974 | SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) | NA |
| UHGV-0004559_5 | Structural annotation | PF01381, PF00717, MF_00015, NF041951, COG1396 | NA | NA |
| UHGV-0004559_6 | KOfam | K07729 | K07729; putative transcriptional regulator | NA |
| UHGV-0004559_6 | PHROG | phrog_5823 | transcriptional regulator | transcription regulation |
| UHGV-0004559_6 | UniRef90 | UniRef90_A0A822LL88 | Toxin-antitoxin system antitoxin component Xre family | NA |
| UHGV-0004559_6 | eggNOG-mapper | 568703.LGG_00374 | DNA-binding helix-turn-helix protein | NA |
| UHGV-0004559_6 | PADLOC | retron_type_VI_hth_cluster2_1 | NA | Retron |
| UHGV-0004559_6 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0004559_6 | COG | COG3620 | Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain CBS pair) | NA |
| UHGV-0004559_6 | Structural annotation | PF01381, NF041951, COG1396 | NA | NA |
| UHGV-0004559_11 | Structural annotation | PF19005 | NA | NA |
| UHGV-0004559_12 | KOfam | K03427 | hsdM; type I restriction enzyme M protein [EC:2.1.1.72] | NA |
| UHGV-0004559_12 | PHROG | phrog_6380 | DNA methyltransferase | other |
| UHGV-0004559_12 | UniRef90 | UniRef90_UPI0019570FFD | N-6 DNA methylase | NA |
| UHGV-0004559_12 | eggNOG-mapper | 1401065.HMPREF2130_08355 | PFAM N-6 DNA methylase | NA |
| UHGV-0004559_12 | PADLOC | MTase_I_00005 | Type I methyltransferase | RM |
| UHGV-0004559_12 | Pfam | PF02384 | N-6 DNA Methylase | N6_Mtase |
| UHGV-0004559_12 | COG | COG0286 | Type I restriction-modification system, DNA methylase subunit | NA |
| UHGV-0004559_12 | Structural annotation | PF02384, MF_01872, TIGR00497, COG0286 | NA | NA |
| UHGV-0004559_13 | UniRef90 | UniRef90_R5VU56 | HTH_11 domain-containing protein | NA |
| UHGV-0004559_13 | Pfam | PF08279 | HTH domain | HTH_11 |
| UHGV-0004559_13 | Structural annotation | PF20063 | NA | NA |
| UHGV-0004559_15 | PHROG | phrog_3584 | replication initiation protein | DNA, RNA and nucleotide metabolism |
| UHGV-0004559_15 | eggNOG-mapper | 1235800.C819_02258 | NA | NA |
| UHGV-0004559_15 | Structural annotation | PF21578, NF041486 | NA | NA |
| UHGV-0004559_16 | KOfam | K03469 | rnhA, RNASEH1; ribonuclease HI [EC:3.1.26.4] | NA |
| UHGV-0004559_16 | PHROG | phrog_531 | Rnase H | DNA, RNA and nucleotide metabolism |
| UHGV-0004559_16 | UniRef90 | UniRef90_R5WND2 | Ribonuclease H | NA |
| UHGV-0004559_16 | eggNOG-mapper | 118005.AWNK01000006_gene1316 | RNA-DNA hybrid ribonuclease activity | NA |
| UHGV-0004559_16 | Pfam | PF00075 | RNase H | RNase_H |
| UHGV-0004559_16 | COG | COG0328 | Ribonuclease HI | NA |
| UHGV-0004559_16 | Structural annotation | PF00075, MF_00042, NF001236, COG0328 | NA | NA |
| UHGV-0004559_17 | eggNOG-mapper | 1280698.AUJS01000007_gene1016 | NA | NA |
| UHGV-0004559_18 | PHROG | phrog_4433 | NA | unknown function |
| UHGV-0004559_18 | eggNOG-mapper | 411459.RUMOBE_01777 | regulation of DNA-templated transcription, elongation | NA |
| UHGV-0004559_18 | COG | COG5164 | Transcription elongation factor SPT5 | NA |
| UHGV-0004559_18 | Structural annotation | PF12120, NF000318 | NA | NA |
| UHGV-0004559_19 | PHROG | phrog_8470 | NA | unknown function |
| UHGV-0004559_19 | UniRef90 | UniRef90_A0A1I3G898 | PcfJ-like protein | NA |
| UHGV-0004559_19 | eggNOG-mapper | 742733.HMPREF9469_00219 | PcfJ-like protein | NA |
| UHGV-0004559_19 | Pfam | PF14284 | PcfJ-like protein | PcfJ |
| UHGV-0004559_19 | Structural annotation | PF14284 | NA | NA |
| UHGV-0004559_20 | PHROG | phrog_15077 | NA | unknown function |
| UHGV-0004559_20 | eggNOG-mapper | 1280698.AUJS01000007_gene1019 | NA | NA |
| UHGV-0004559_20 | Structural annotation | PF11300, NF038070 | NA | NA |
| UHGV-0004559_21 | UniRef90 | UniRef90_A0A417WAJ1 | HNH endonuclease | NA |
| UHGV-0004559_21 | eggNOG-mapper | 1235800.C819_02254 | HNH nucleases | NA |
| UHGV-0004559_22 | eggNOG-mapper | 1235800.C819_02253 | NA | NA |
| UHGV-0004559_23 | UniRef90 | UniRef90_R5W1M0 | NA | NA |
| UHGV-0004559_23 | Pfam | PF19789 | NA | DUF6273 |
| UHGV-0004559_23 | Structural annotation | PF19789 | NA | NA |
| UHGV-0004559_24 | PHROG | phrog_625 | NA | unknown function |
| UHGV-0004559_24 | UniRef90 | UniRef90_A0A373D1H8 | ASCH domain-containing protein | NA |
| UHGV-0004559_24 | eggNOG-mapper | 397290.C810_01502 | NA | NA |
| UHGV-0004559_24 | Structural annotation | PF12961, NF003443, COG2947 | NA | NA |
| UHGV-0004559_28 | KOfam | K03698 | cbf, cbf1; 3'-5' exoribonuclease [EC:3.1.-.-] | NA |
| UHGV-0004559_28 | PHROG | phrog_5889 | NA | unknown function |
| UHGV-0004559_28 | UniRef90 | UniRef90_A0A843HIF4 | HDIG domain-containing protein | NA |
| UHGV-0004559_28 | eggNOG-mapper | 1235800.C819_00499 | metal-dependent phosphohydrolase, HD sub domain | NA |
| UHGV-0004559_28 | COG | COG3481 | 3'-5' exoribonuclease YhaM, can participate in 23S rRNA maturation, HD superfamily | NA |
| UHGV-0004559_28 | Structural annotation | PF21447, MF_01427, NF010007, COG3481 | NA | NA |
| UHGV-0004559_29 | Structural annotation | PF06530, TIGR02937, COG2739 | NA | NA |
| UHGV-0004559_30 | PHROG | phrog_1129 | holin | lysis |
| UHGV-0004559_30 | UniRef90 | UniRef90_UPI000485FFFD | phage holin family protein | NA |
| UHGV-0004559_30 | eggNOG-mapper | 1304866.K413DRAFT_0135 | Phage holin family Hol44, in holin superfamily V | NA |
| UHGV-0004559_30 | Pfam | PF16079 | Phage holin family Hol44, in holin superfamily V | Phage_holin_5_2 |
| UHGV-0004559_30 | Structural annotation | PF16079 | NA | NA |
| UHGV-0004559_31 | PHROG | phrog_1863 | NA | unknown function |
| UHGV-0004559_31 | eggNOG-mapper | 1203606.HMPREF1526_02027 | NA | NA |
| UHGV-0004559_32 | KOfam | K01447 | xlyAB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | NA |
| UHGV-0004559_32 | PHROG | phrog_15001 | endolysin | lysis |
| UHGV-0004559_32 | UniRef90 | UniRef90_R5WDY6 | N-acetylmuramyl-L-alanine amidase negative regulator of AmpC AmpD | NA |
| UHGV-0004559_32 | eggNOG-mapper | 1235835.C814_01292 | Ami_2 | NA |
| UHGV-0004559_32 | Pfam | PF01510 | N-acetylmuramoyl-L-alanine amidase | Amidase_2 |
| UHGV-0004559_32 | COG | COG1388 | LysM repeat | NA |
| UHGV-0004559_32 | Structural annotation | PF01510, PF18342, MF_04111, COG5632 | NA | NA |
| UHGV-0004559_33 | KOfam | K07474 | xtmA; phage terminase small subunit | NA |
| UHGV-0004559_33 | PHROG | phrog_51 | terminase small subunit | head and packaging |
| UHGV-0004559_33 | UniRef90 | UniRef90_UPI0004826165 | terminase small subunit | NA |
| UHGV-0004559_33 | eggNOG-mapper | 702450.CUW_0530 | Terminase Small Subunit | NA |
| UHGV-0004559_33 | Pfam | PF03592 | Terminase small subunit | Terminase_2 |
| UHGV-0004559_33 | COG | COG3728 | Phage terminase, small subunit | NA |
| UHGV-0004559_33 | Structural annotation | PF03592, COG3728 | NA | NA |
| UHGV-0004559_34 | PHROG | phrog_4581 | terminase small subunit | head and packaging |
| UHGV-0004559_34 | UniRef90 | UniRef90_R5W1L1 | HNH domain-containing protein | NA |
| UHGV-0004559_34 | eggNOG-mapper | 1157490.EL26_20750 | HNH endonuclease | NA |
| UHGV-0004559_34 | Pfam | PF01844 | HNH endonuclease | HNH |
| UHGV-0004559_34 | COG | COG1403 | 5-methylcytosine-specific restriction endonuclease McrA | NA |
| UHGV-0004559_34 | Structural annotation | PF13671, MF_03171, NF005251, NF008448, COG4639 | NA | NA |
| UHGV-0004559_37 | PHROG | phrog_9 | terminase large subunit | head and packaging |
| UHGV-0004559_37 | UniRef90 | UniRef90_R7FEF5 | Terminase | NA |
| UHGV-0004559_37 | eggNOG-mapper | 1211817.CCAT010000007_gene1040 | Terminase | NA |
| UHGV-0004559_37 | Pfam | PF03354 | Terminase large subunit, ATPase domain | TerL_ATPase |
| UHGV-0004559_37 | Pfam | PF20441 | Terminase large subunit, endonuclease domain | TerL_nuclease |
| UHGV-0004559_37 | COG | COG4626 | Phage terminase-like protein, large subunit, contains N-terminal HTH domain | NA |
| UHGV-0004559_37 | Structural annotation | PF20441, PF03354, MF_04145, TIGR01547, COG4626 | NA | NA |
| UHGV-0004559_38 | PHROG | phrog_12 | portal protein | head and packaging |
| UHGV-0004559_38 | UniRef90 | UniRef90_R5VU10 | Phage portal protein | NA |
| UHGV-0004559_38 | eggNOG-mapper | 293826.Amet_2412 | Portal protein | NA |
| UHGV-0004559_38 | Pfam | PF04860 | Phage portal protein | Phage_portal |
| UHGV-0004559_38 | COG | COG4695 | Phage portal protein BeeE | NA |
| UHGV-0004559_38 | Structural annotation | PF04860, MF_04135, TIGR01537, COG4695 | NA | NA |
| UHGV-0004559_39 | KOfam | K06904 | NA | NA |
| UHGV-0004559_39 | PHROG | phrog_80 | head maturation protease | head and packaging |
| UHGV-0004559_39 | UniRef90 | UniRef90_R5W1K4 | Putative phage prohead protease | NA |
| UHGV-0004559_39 | eggNOG-mapper | 927704.SELR_18200 | Caudovirus prohead serine protease | NA |
| UHGV-0004559_39 | Pfam | PF04586 | Caudovirus prohead serine protease | Peptidase_S78 |
| UHGV-0004559_39 | NCBIFam | TIGR01543.1 | HK97 family phage prohead protease | NA |
| UHGV-0004559_39 | COG | COG3740 | Phage head maturation protease | NA |
| UHGV-0004559_39 | Structural annotation | PF04586, TIGR01543, COG3740 | NA | NA |
| UHGV-0004559_40 | PHROG | phrog_10 | major head protein | head and packaging |
| UHGV-0004559_40 | UniRef90 | UniRef90_R5VT22 | Phage major capsid protein HK97 family | NA |
| UHGV-0004559_40 | eggNOG-mapper | 411470.RUMGNA_02065 | NA | NA |
| UHGV-0004559_40 | Pfam | PF05065 | Phage capsid family | Phage_capsid |
| UHGV-0004559_40 | NCBIFam | TIGR01554.2 | phage major capsid protein | NA |
| UHGV-0004559_40 | COG | COG4653 | Predicted phage phi-C31 gp36 major capsid-like protein | NA |
| UHGV-0004559_40 | Structural annotation | PF05065, PF19962, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0004559_41 | Structural annotation | PF05135, TIGR01560 | NA | NA |
| UHGV-0004559_42 | UniRef90 | UniRef90_R5WDX4 | Putative phage head-tail adaptor | NA |
| UHGV-0004559_42 | eggNOG-mapper | 1536774.H70357_10645 | NA | NA |
| UHGV-0004559_42 | Pfam | PF05521 | Phage head-tail joining protein | Phage_H_T_join |
| UHGV-0004559_42 | NCBIFam | TIGR01563.1 | phage head closure protein | NA |
| UHGV-0004559_42 | Structural annotation | PF05521, TIGR01563, COG5614 | NA | NA |
| UHGV-0004559_43 | Structural annotation | TIGR01725 | NA | NA |
| UHGV-0004559_44 | Structural annotation | PF05657 | NA | NA |
| UHGV-0004559_45 | PHROG | phrog_88 | major tail protein | tail |
| UHGV-0004559_45 | UniRef90 | UniRef90_A0A843GGC8 | S-l_SbsC_C domain-containing protein | NA |
| UHGV-0004559_45 | eggNOG-mapper | 696281.Desru_3543 | phage major tail protein | NA |
| UHGV-0004559_45 | Pfam | PF04630 | Phage tail tube protein | Phage_TTP_1 |
| UHGV-0004559_45 | NCBIFam | TIGR01603.1 | major tail protein | NA |
| UHGV-0004559_45 | COG | COG5492 | NA | NA |
| UHGV-0004559_45 | Structural annotation | PF04630, TIGR01603, COG3498 | NA | NA |
| UHGV-0004559_47 | PHROG | phrog_1533 | tail length tape measure protein | tail |
| UHGV-0004559_47 | UniRef90 | UniRef90_R5WDX0 | Phage tail tape measure protein TP901 family | NA |
| UHGV-0004559_47 | eggNOG-mapper | 537007.BLAHAN_04244 | Phage tail tape measure protein, TP901 family | NA |
| UHGV-0004559_47 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-0004559_47 | NCBIFam | TIGR01760.1 | phage tail tape measure protein | NA |
| UHGV-0004559_47 | COG | COG5283 | Phage-related tail protein | NA |
| UHGV-0004559_47 | Structural annotation | PF10145, TIGR01760, COG5280 | NA | NA |
| UHGV-0004559_48 | UniRef90 | UniRef90_A0A6N2W6N8 | Phage tail protein | NA |
| UHGV-0004559_48 | eggNOG-mapper | 428125.CLOLEP_01423 | Phage tail protein | NA |
| UHGV-0004559_48 | Pfam | PF05709 | Phage tail protein RIFT-related domain | Sipho_tail |
| UHGV-0004559_51 | PHROG | phrog_36410 | NA | unknown function |
| UHGV-0004559_51 | eggNOG-mapper | 411473.RUMCAL_02824 | NA | NA |
| UHGV-0004559_51 | COG | COG4722 | Phage-related protein YomH | NA |
| UHGV-0004559_52 | PHROG | phrog_538 | minor tail protein | tail |
| UHGV-0004559_52 | UniRef90 | UniRef90_UPI0004813F81 | siphovirus ReqiPepy6 Gp37-like family protein | NA |
| UHGV-0004559_52 | eggNOG-mapper | 742740.HMPREF9474_02260 | Siphovirus ReqiPepy6 Gp37-like protein | NA |
| UHGV-0004559_52 | Pfam | PF14594 | Siphovirus ReqiPepy6 Gp37-like protein | Sipho_Gp37 |
| UHGV-0004559_52 | Structural annotation | PF14594, TIGR01665, COG4926 | NA | NA |
| UHGV-0004559_53 | PHROG | phrog_1220 | head protein | head and packaging |
| UHGV-0004559_53 | eggNOG-mapper | 536232.CLM_2920 | NA | NA |
| UHGV-0004559_53 | Structural annotation | PF20747 | NA | NA |
| UHGV-0004559_54 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-0004559_54 | UniRef90 | UniRef90_A0A173W8E7 | Helix-turn-helix | NA |
| UHGV-0004559_54 | eggNOG-mapper | 411474.COPEUT_00075 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-0004559_54 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0004559_54 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |