| UHGV-0448429_1 | PHROG | phrog_338 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0448429_1 | UniRef90 | UniRef90_UPI0015708A7C | HNH endonuclease | NA |
| UHGV-0448429_1 | eggNOG-mapper | 1280698.AUJS01000007_gene1032 | HNH endonuclease domain protein | NA |
| UHGV-0448429_1 | Pfam | PF01844 | HNH endonuclease | HNH |
| UHGV-0448429_1 | COG | COG1403 | 5-methylcytosine-specific restriction endonuclease McrA | NA |
| UHGV-0448429_1 | Structural annotation | PF01844 | NA | NA |
| UHGV-0448429_2 | PHROG | phrog_36 | transcriptional regulator | transcription regulation |
| UHGV-0448429_2 | eggNOG-mapper | 742765.HMPREF9457_02116 | NA | NA |
| UHGV-0448429_2 | Structural annotation | PF02996 | NA | NA |
| UHGV-0448429_4 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-0448429_4 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-0448429_4 | UniRef90 | UniRef90_A0A8B3BSU1 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-0448429_4 | eggNOG-mapper | 742740.HMPREF9474_04317 | C-5 cytosine-specific DNA methylase | NA |
| UHGV-0448429_4 | PADLOC | MTase_II_00020 | Type II methyltransferase | RM |
| UHGV-0448429_4 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-0448429_4 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-0448429_4 | Structural annotation | PF00145, TIGR00675, COG0270 | NA | NA |
| UHGV-0448429_6 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-0448429_6 | UniRef90 | UniRef90_A0A2H4JC51 | Putative 3'-phosphoadenosine 5'-phosphosulfatesulfotransferase/FAD synthetase-related enzyme | NA |
| UHGV-0448429_6 | eggNOG-mapper | 33035.JPJF01000123_gene2435 | NA | NA |
| UHGV-0448429_6 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-0448429_7 | PHROG | phrog_15198 | NA | unknown function |
| UHGV-0448429_7 | UniRef90 | UniRef90_UPI0008DB1FD6 | NA | NA |
| UHGV-0448429_7 | eggNOG-mapper | 665950.HMPREF1025_02540 | NA | NA |
| UHGV-0448429_7 | Pfam | PF04448 | NA | DUF551 |
| UHGV-0448429_8 | PHROG | phrog_419 | NA | unknown function |
| UHGV-0448429_8 | eggNOG-mapper | 762660.E5EYD7_9CAUD | NA | NA |
| UHGV-0448429_8 | Structural annotation | PF14083 | NA | NA |
| UHGV-0448429_11 | PHROG | phrog_8684 | NA | unknown function |
| UHGV-0448429_11 | UniRef90 | UniRef90_A0A372UJN3 | YopX domain-containing protein | NA |
| UHGV-0448429_11 | eggNOG-mapper | 397290.C810_01526 | YopX protein | NA |
| UHGV-0448429_11 | Pfam | PF09643 | YopX protein | YopX |
| UHGV-0448429_11 | Structural annotation | PF09643, TIGR01671 | NA | NA |
| UHGV-0448429_12 | PHROG | phrog_16351 | DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0448429_12 | UniRef90 | UniRef90_UPI001D072F7E | NA | NA |
| UHGV-0448429_12 | eggNOG-mapper | 428127.EUBDOL_01238 | NA | NA |
| UHGV-0448429_13 | PHROG | phrog_10192 | NA | unknown function |
| UHGV-0448429_14 | KOfam | K01356 | lexA; repressor LexA [EC:3.4.21.88] | NA |
| UHGV-0448429_14 | PHROG | phrog_3502 | NA | unknown function |
| UHGV-0448429_14 | UniRef90 | UniRef90_A0A174J3W3 | LexA repressor | NA |
| UHGV-0448429_14 | eggNOG-mapper | 545697.HMPREF0216_00360 | Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair | NA |
| UHGV-0448429_14 | Pfam | PF01726 | LexA DNA binding domain | LexA_DNA_bind |
| UHGV-0448429_14 | COG | COG1974 | SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) | NA |
| UHGV-0448429_14 | Structural annotation | PF01726, MF_00732, NF006812, COG3388 | NA | NA |
| UHGV-0448429_16 | PHROG | phrog_7566 | NA | unknown function |
| UHGV-0448429_16 | eggNOG-mapper | 97139.C824_00037 | NA | NA |
| UHGV-0448429_17 | PHROG | phrog_17690 | NA | unknown function |
| UHGV-0448429_18 | PHROG | phrog_26445 | NA | unknown function |
| UHGV-0448429_19 | KOfam | K03469 | rnhA, RNASEH1; ribonuclease HI [EC:3.1.26.4] | NA |
| UHGV-0448429_19 | PHROG | phrog_531 | Rnase H | DNA, RNA and nucleotide metabolism |
| UHGV-0448429_19 | UniRef90 | UniRef90_A0A894KKE1 | RNase H type-1 domain-containing protein | NA |
| UHGV-0448429_19 | eggNOG-mapper | 555779.Dthio_PD3035 | Endonuclease that specifically degrades the RNA of RNA- DNA hybrids | NA |
| UHGV-0448429_19 | Pfam | PF00075 | RNase H | RNase_H |
| UHGV-0448429_19 | COG | COG0328 | Ribonuclease HI | NA |
| UHGV-0448429_19 | Structural annotation | PF00075, MF_00042, NF001236, COG0328 | NA | NA |
| UHGV-0448429_20 | PHROG | phrog_3584 | replication initiation protein | DNA, RNA and nucleotide metabolism |
| UHGV-0448429_20 | eggNOG-mapper | 1280698.AUJS01000007_gene1013 | NA | NA |
| UHGV-0448429_20 | Structural annotation | PF21578, NF041486 | NA | NA |
| UHGV-0448429_29 | KOfam | K18830 | pezA; HTH-type transcriptional regulator / antitoxin PezA | NA |
| UHGV-0448429_29 | PHROG | phrog_4 | transcriptional repressor | transcription regulation |
| UHGV-0448429_29 | UniRef90 | UniRef90_UPI001BC85B83 | helix-turn-helix domain-containing protein | NA |
| UHGV-0448429_29 | eggNOG-mapper | 411471.SUBVAR_05818 | sequence-specific DNA binding | NA |
| UHGV-0448429_29 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0448429_29 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0448429_29 | Structural annotation | PF01381, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-0448429_31 | eggNOG-mapper | 511680.BUTYVIB_01634 | NA | NA |
| UHGV-0448429_31 | Structural annotation | PF02701 | NA | NA |
| UHGV-0448429_32 | UniRef90 | UniRef90_A0A8E3MW32 | NA | NA |
| UHGV-0448429_32 | eggNOG-mapper | 440512.C211_23350 | NA | NA |
| UHGV-0448429_32 | Pfam | PF09858 | NA | DUF2085 |
| UHGV-0448429_32 | COG | COG3815 | NA | NA |
| UHGV-0448429_32 | Structural annotation | PF09858, COG3815 | NA | NA |
| UHGV-0448429_33 | KOfam | K06400 | spoIVCA; site-specific DNA recombinase | NA |
| UHGV-0448429_33 | PHROG | phrog_95 | integrase | integration and excision |
| UHGV-0448429_33 | UniRef90 | UniRef90_A0A894KEI4 | Recombinase | NA |
| UHGV-0448429_33 | eggNOG-mapper | 1256908.HMPREF0373_00206 | Resolvase, N terminal domain | NA |
| UHGV-0448429_33 | Pfam | PF00239 | Resolvase, N terminal domain | Resolvase |
| UHGV-0448429_33 | Pfam | PF07508 | Recombinase | Recombinase |
| UHGV-0448429_33 | COG | COG1961 | Site-specific DNA recombinase SpoIVCA/DNA invertase PinE | NA |
| UHGV-0448429_33 | Structural annotation | PF07508, PF00239, NF041201, COG1961 | NA | NA |
| UHGV-0448429_34 | KOfam | K01447 | xlyAB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | NA |
| UHGV-0448429_34 | PHROG | phrog_3088 | amidase | lysis |
| UHGV-0448429_34 | UniRef90 | UniRef90_A0A894KKA6 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0448429_34 | eggNOG-mapper | 428125.CLOLEP_01782 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0448429_34 | Pfam | PF01510 | N-acetylmuramoyl-L-alanine amidase | Amidase_2 |
| UHGV-0448429_34 | COG | COG5632 | N-acetylmuramoyl-L-alanine amidase CwlA | NA |
| UHGV-0448429_34 | Structural annotation | PF01510, MF_04111, NF008758, COG5632 | NA | NA |
| UHGV-0448429_35 | PHROG | phrog_18218 | NA | unknown function |
| UHGV-0448429_35 | UniRef90 | UniRef90_A0A396PU34 | Ribonuclease | NA |
| UHGV-0448429_35 | eggNOG-mapper | 658655.HMPREF0988_02546 | NA | NA |
| UHGV-0448429_35 | Structural annotation | PF06946 | NA | NA |
| UHGV-0448429_36 | UniRef90 | UniRef90_A0A3R6SMZ1 | CTP synthase | NA |
| UHGV-0448429_36 | eggNOG-mapper | 411490.ANACAC_00599 | NA | NA |
| UHGV-0448429_37 | PHROG | phrog_2310 | NA | unknown function |
| UHGV-0448429_37 | eggNOG-mapper | 632245.CLP_2682 | NA | NA |
| UHGV-0448429_38 | PHROG | phrog_19695 | NA | unknown function |
| UHGV-0448429_38 | eggNOG-mapper | 411470.RUMGNA_00122 | NA | NA |
| UHGV-0448429_39 | PHROG | phrog_1382 | NA | unknown function |
| UHGV-0448429_39 | NCBIFam | NF040910.1 | CD1375 family protein | NA |
| UHGV-0448429_39 | Structural annotation | NF040910 | NA | NA |
| UHGV-0448429_40 | PHROG | phrog_12931 | NA | unknown function |
| UHGV-0448429_40 | eggNOG-mapper | 742723.HMPREF9477_00891 | NA | NA |
| UHGV-0448429_40 | Structural annotation | PF17642 | NA | NA |
| UHGV-0448429_42 | PHROG | phrog_9994 | NA | unknown function |
| UHGV-0448429_42 | UniRef90 | UniRef90_A0A7K3I4P1 | H_lectin domain-containing protein | NA |
| UHGV-0448429_42 | eggNOG-mapper | 411468.CLOSCI_02412 | NA | NA |
| UHGV-0448429_43 | PHROG | phrog_538 | minor tail protein | tail |
| UHGV-0448429_43 | UniRef90 | UniRef90_UPI001E30CCA1 | siphovirus ReqiPepy6 Gp37-like family protein | NA |
| UHGV-0448429_43 | eggNOG-mapper | 411468.CLOSCI_00276 | NA | NA |
| UHGV-0448429_43 | Pfam | PF14594 | Siphovirus ReqiPepy6 Gp37-like protein | Sipho_Gp37 |
| UHGV-0448429_43 | Structural annotation | PF14594, TIGR01665, COG4379 | NA | NA |
| UHGV-0448429_44 | PHROG | phrog_33 | distal tail protein Dit | tail |
| UHGV-0448429_44 | UniRef90 | UniRef90_UPI001F242491 | phage tail family protein | NA |
| UHGV-0448429_44 | eggNOG-mapper | 1280698.AUJS01000007_gene1048 | NA | NA |
| UHGV-0448429_44 | Structural annotation | PF16774, TIGR01633, COG4722 | NA | NA |
| UHGV-0448429_45 | PHROG | phrog_6900 | tail length tape measure protein | tail |
| UHGV-0448429_45 | UniRef90 | UniRef90_A0A1C5Y9X6 | Phage-related protein | NA |
| UHGV-0448429_45 | eggNOG-mapper | 665950.HMPREF1025_02522 | Phage tail tape measure protein, TP901 family | NA |
| UHGV-0448429_45 | COG | COG1511 | NA | NA |
| UHGV-0448429_45 | Structural annotation | PF20155, MF_04138, COG5281 | NA | NA |
| UHGV-0448429_46 | PHROG | phrog_1633 | NA | unknown function |
| UHGV-0448429_46 | UniRef90 | UniRef90_UPI0006C2F0F2 | NA | NA |
| UHGV-0448429_46 | eggNOG-mapper | 665950.HMPREF1025_02523 | NA | NA |
| UHGV-0448429_46 | Pfam | PF17318 | NA | DUF5361 |
| UHGV-0448429_46 | Structural annotation | PF17318 | NA | NA |
| UHGV-0448429_47 | PHROG | phrog_1526 | NA | unknown function |
| UHGV-0448429_47 | eggNOG-mapper | 665950.HMPREF1025_02524 | NA | NA |
| UHGV-0448429_48 | PHROG | phrog_117 | major tail protein | tail |
| UHGV-0448429_48 | UniRef90 | UniRef90_UPI00156E6ACC | phage tail protein | NA |
| UHGV-0448429_48 | eggNOG-mapper | 665950.HMPREF1025_02525 | domain, Protein | NA |
| UHGV-0448429_48 | COG | COG5492 | NA | NA |
| UHGV-0448429_48 | Structural annotation | PF04630, TIGR01603, COG5437 | NA | NA |
| UHGV-0448429_49 | PHROG | phrog_123 | tail terminator | connector |
| UHGV-0448429_49 | eggNOG-mapper | 1280698.AUJS01000007_gene1043 | NA | NA |
| UHGV-0448429_49 | Structural annotation | PF06141 | NA | NA |
| UHGV-0448429_50 | eggNOG-mapper | 908337.HMPREF9257_0534 | NA | NA |
| UHGV-0448429_51 | PHROG | phrog_501 | head closure Hc1 | connector |
| UHGV-0448429_51 | eggNOG-mapper | 665950.HMPREF1025_02528 | NA | NA |
| UHGV-0448429_51 | Structural annotation | PF12206, COG5614 | NA | NA |
| UHGV-0448429_52 | PHROG | phrog_137 | head-tail adaptor Ad1 | connector |
| UHGV-0448429_52 | UniRef90 | UniRef90_A0A8B6J3T0 | Phage Gp19/Gp15/Gp42 family protein | NA |
| UHGV-0448429_52 | eggNOG-mapper | 663952.SDD27957_07255 | Phage protein Gp19/Gp15/Gp42 | NA |
| UHGV-0448429_52 | Pfam | PF09355 | NA | Phage_Gp19 |
| UHGV-0448429_52 | Structural annotation | PF09355 | NA | NA |
| UHGV-0448429_54 | PHROG | phrog_32396 | NA | unknown function |
| UHGV-0448429_54 | UniRef90 | UniRef90_A0A1C5MLP2 | Phage capsid family | NA |
| UHGV-0448429_54 | eggNOG-mapper | 665950.HMPREF1025_02530 | Phage capsid family | NA |
| UHGV-0448429_54 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0448429_55 | PHROG | phrog_233 | head scaffolding protein | head and packaging |
| UHGV-0448429_55 | UniRef90 | UniRef90_UPI001961E2FD | NA | NA |
| UHGV-0448429_55 | eggNOG-mapper | 665950.HMPREF1025_02531 | NA | NA |
| UHGV-0448429_55 | Pfam | PF14265 | NA | DUF4355 |
| UHGV-0448429_55 | Structural annotation | PF14265 | NA | NA |
| UHGV-0448429_56 | PHROG | phrog_17688 | NA | unknown function |
| UHGV-0448429_56 | UniRef90 | UniRef90_A0A1C5Y909 | Phage terminase-like protein, large subunit | NA |
| UHGV-0448429_56 | eggNOG-mapper | 665950.HMPREF1025_02532 | phage terminase, large subunit | NA |
| UHGV-0448429_56 | COG | COG4626 | Phage terminase-like protein, large subunit, contains N-terminal HTH domain | NA |
| UHGV-0448429_56 | Structural annotation | PF20441, PF03354, MF_04146, NF033889, COG4626 | NA | NA |
| UHGV-0448429_57 | PHROG | phrog_2494 | minor head protein | head and packaging |
| UHGV-0448429_57 | UniRef90 | UniRef90_A0A1C5MKJ0 | Ntox50 domain-containing protein | NA |
| UHGV-0448429_57 | eggNOG-mapper | 665950.HMPREF1025_02536 | NA | NA |
| UHGV-0448429_58 | PHROG | phrog_104 | portal protein | head and packaging |
| UHGV-0448429_58 | UniRef90 | UniRef90_A0A1C5MKT6 | Phage portal protein, SPP1 Gp6-like | NA |
| UHGV-0448429_58 | eggNOG-mapper | 665950.HMPREF1025_02537 | Phage portal protein, SPP1 Gp6-like | NA |
| UHGV-0448429_58 | Structural annotation | PF05133, MF_04120, TIGR01538, COG3567 | NA | NA |