vOTU-061651

Overview

vOTU representative UHGV-0196480

No. of genomes 4

Genome length 46,995 bps

Completeness 99.23% (high-quality)

Host Megasphaeraceae

Prediction confidence Confident

vOTU information
vOTU ID	vOTU-061651
Number of genomes	4
Taxonomy (ICTV)	Duplodnaviria › Heunggongvirae › Uroviricota › Caudoviricetes
Taxonomy (UHGV)	vFAM-00001 › vSUBFAM-01095 › vGENUS-05671 › vSUBGEN-16475 › vOTU-061651
Host taxonomy	Bacteria › Firmicutes C › Negativicutes › Veillonellales › Megasphaeraceae
Host range breadth	Family
Host prediction method	CRISPR
Lifestyle	Temperate (evidence: integrase)

Representative genome
Genome ID	UHGV-0196480
BioSample	SAMN00998693
Genome length	46,995 bps
CheckV completeness	99.23% (high-quality)
CheckV contamination	0.00%
CDS count	66
CDS density	90.37%
tRNA count	0
Integrase	Yes
Viral confidence	Confident

Representative genome content

Select view: Genome viewer Functional annotation

Functional annotation

Gene ID	Reference	Reference ID	Information	Category
UHGV-0196480_2	KOfam	K14059	int; integrase	NA
UHGV-0196480_2	PHROG	phrog_1	integrase	integration and excision
UHGV-0196480_2	UniRef90	UniRef90_S7HSJ4	Site-specific recombinase	NA
UHGV-0196480_2	eggNOG-mapper	1273103.NM10_02432	Phage integrase family	NA
UHGV-0196480_2	Pfam	PF14659	Phage integrase, N-terminal SAM-like domain	Phage_int_SAM_3
UHGV-0196480_2	Pfam	PF00589	Phage integrase family	Phage_integrase
UHGV-0196480_2	COG	COG0582	Integrase/recombinase, includes phage integrase	NA
UHGV-0196480_2	Structural annotation	PF00589, PF14659, MF_02055, TIGR02224, COG4974	NA	NA
UHGV-0196480_3	PHROG	phrog_2655	excisionase	integration and excision
UHGV-0196480_3	UniRef90	UniRef90_A0A2S0MA68	HTH_59 domain-containing protein	NA
UHGV-0196480_3	eggNOG-mapper	1111454.HMPREF1250_0298	NA	NA
UHGV-0196480_3	Pfam	PF20038	Helix-turn-helix domain	HTH_59
UHGV-0196480_3	Structural annotation	PF20038, TIGR01764	NA	NA
UHGV-0196480_4	PHROG	phrog_10797	NA	unknown function
UHGV-0196480_4	UniRef90	UniRef90_A0A0X8K8T8	Glycoprotease	NA
UHGV-0196480_4	eggNOG-mapper	1273103.NM10_03026	NA	NA
UHGV-0196480_4	Structural annotation	PF06531	NA	NA
UHGV-0196480_5	KOfam	K07273	acm; lysozyme	NA
UHGV-0196480_5	PHROG	phrog_6745	endolysin	lysis
UHGV-0196480_5	UniRef90	UniRef90_A0A0U1L0T6	Glycosyl hydrolase, family 25	NA
UHGV-0196480_5	eggNOG-mapper	1232428.CAVO010000067_gene417	Glycosyl hydrolases family 25	NA
UHGV-0196480_5	Pfam	PF01183	Glycosyl hydrolases family 25	Glyco_hydro_25
UHGV-0196480_5	COG	COG3757	Lyzozyme M1 (1,4-beta-N-acetylmuramidase), GH25 family	NA
UHGV-0196480_5	Structural annotation	PF01183, NF008377, COG3757	NA	NA
UHGV-0196480_6	eggNOG-mapper	1327935.A0A060AMX0_9CAUD	NA	NA
UHGV-0196480_7	PHROG	phrog_28789	NA	unknown function
UHGV-0196480_7	UniRef90	UniRef90_R7MZN4	Conserved domain protein	NA
UHGV-0196480_7	eggNOG-mapper	1273103.NM10_03036	NA	NA
UHGV-0196480_8	PHROG	phrog_4105	NA	unknown function
UHGV-0196480_8	eggNOG-mapper	706434.HMPREF9429_00642	NA	NA
UHGV-0196480_9	KOfam	K14059	int; integrase	NA
UHGV-0196480_9	PHROG	phrog_1	integrase	integration and excision
UHGV-0196480_9	UniRef90	UniRef90_UPI000404EDAD	site-specific integrase	NA
UHGV-0196480_9	eggNOG-mapper	568816.Acin_1821	Phage integrase family	NA
UHGV-0196480_9	Pfam	PF00589	Phage integrase family	Phage_integrase
UHGV-0196480_9	COG	COG0582	Integrase/recombinase, includes phage integrase	NA
UHGV-0196480_9	Structural annotation	PF00589, MF_01808, NF007246, COG4974	NA	NA
UHGV-0196480_11	PHROG	phrog_33356	NA	unknown function
UHGV-0196480_11	UniRef90	UniRef90_G4Q8U0	Side tail fiber protein from lambdoid prophage Rac	NA
UHGV-0196480_11	eggNOG-mapper	568816.Acin_1822	Collagen triple helix repeat (20 copies)	NA
UHGV-0196480_11	COG	COG3266	Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain	NA
UHGV-0196480_12	PHROG	phrog_19099	NA	unknown function
UHGV-0196480_13	PHROG	phrog_6061	NA	unknown function
UHGV-0196480_15	PHROG	phrog_31	baseplate hub protein Tal	tail
UHGV-0196480_15	UniRef90	UniRef90_S7HS92	Phage-tail_3 domain-containing protein	NA
UHGV-0196480_15	eggNOG-mapper	1273103.NM10_03076	cellulase activity	NA
UHGV-0196480_15	Pfam	PF13550	Putative phage tail protein	Phage-tail_3
UHGV-0196480_15	COG	COG1511	NA	NA
UHGV-0196480_15	Structural annotation	PF13550, PF00041, PF09294, PF17936, PF14109, NF040662, NF041335, COG4733	NA	NA
UHGV-0196480_16	KOfam	K13695	nlpC; probable lipoprotein NlpC	NA
UHGV-0196480_16	PHROG	phrog_329	minor tail protein	tail
UHGV-0196480_16	UniRef90	UniRef90_S7HS93	NlpC/P60 domain-containing protein	NA
UHGV-0196480_16	eggNOG-mapper	1273103.NM10_03081	NlpC/P60 family	NA
UHGV-0196480_16	Pfam	PF00877	NlpC/P60 family	NLPC_P60
UHGV-0196480_16	COG	COG0791	Cell wall-associated hydrolase, NlpC_P60 family	NA
UHGV-0196480_16	Structural annotation	PF00877, NF008096, COG0791	NA	NA
UHGV-0196480_17	PHROG	phrog_18	minor tail protein	tail
UHGV-0196480_17	UniRef90	UniRef90_S7HS09	Phage-like protein	NA
UHGV-0196480_17	eggNOG-mapper	1273103.NM10_03086	Phage minor tail protein L	NA
UHGV-0196480_17	Pfam	PF05100	Phage minor tail protein L	Phage_tail_L
UHGV-0196480_17	COG	COG4672	Phage tail protein	NA
UHGV-0196480_17	Structural annotation	PF08875, TIGR01600, COG4672	NA	NA
UHGV-0196480_18	PHROG	phrog_384	virion structural protein	head and packaging
UHGV-0196480_18	UniRef90	UniRef90_UPI001032B7DB	phage tail protein	NA
UHGV-0196480_18	eggNOG-mapper	1273103.NM10_03091	NA	NA
UHGV-0196480_18	Structural annotation	PF05939, TIGR02217, COG4718	NA	NA
UHGV-0196480_19	PHROG	phrog_30973	NA	unknown function
UHGV-0196480_19	UniRef90	UniRef90_UPI0018C794CE	transglycosylase SLT domain-containing protein	NA
UHGV-0196480_19	eggNOG-mapper	1273103.NM10_03096	nuclear chromosome segregation	NA
UHGV-0196480_19	COG	COG3941	Phage tail tape-measure protein, controls tail length	NA
UHGV-0196480_19	Structural annotation	TIGR01760	NA	NA
UHGV-0196480_20	PHROG	phrog_680	tail length tape measure protein	tail
UHGV-0196480_20	eggNOG-mapper	1121440.AUMA01000011_gene2396	NA	NA
UHGV-0196480_20	Pfam	PF08809	NA	DUF1799
UHGV-0196480_21	PHROG	phrog_33144	NA	unknown function
UHGV-0196480_21	eggNOG-mapper	1273103.NM10_03106	NA	NA
UHGV-0196480_22	PHROG	phrog_290	minor tail protein	tail
UHGV-0196480_22	UniRef90	UniRef90_UPI00069D7D9F	phage tail tube protein	NA
UHGV-0196480_22	eggNOG-mapper	1273103.NM10_03111	NA	NA
UHGV-0196480_22	Pfam	PF18906	Phage tail tube protein	Phage_tube_2
UHGV-0196480_22	Structural annotation	PF18906, TIGR02241, TIGR02126, COG5437, COG3498	NA	NA
UHGV-0196480_23	PHROG	phrog_17431	NA	unknown function
UHGV-0196480_23	eggNOG-mapper	1273103.NM10_03116	NA	NA
UHGV-0196480_24	eggNOG-mapper	1273103.NM10_03121	NA	NA
UHGV-0196480_24	Structural annotation	PF05069, TIGR01725	NA	NA
UHGV-0196480_25	PHROG	phrog_36202	NA	unknown function
UHGV-0196480_26	PHROG	phrog_36232	NA	unknown function
UHGV-0196480_27	PHROG	phrog_29	major head protein	head and packaging
UHGV-0196480_27	UniRef90	UniRef90_A0A259UD55	Phage major capsid protein E	NA
UHGV-0196480_27	eggNOG-mapper	1273103.NM10_03136	Phage major capsid protein E	NA
UHGV-0196480_27	Pfam	PF03864	Phage major capsid protein E	Phage_cap_E
UHGV-0196480_27	Structural annotation	PF03864, MF_04133, TIGR04387, COG4653	NA	NA
UHGV-0196480_28	PHROG	phrog_49	head decoration	head and packaging
UHGV-0196480_28	UniRef90	UniRef90_UPI0018C49529	head decoration protein	NA
UHGV-0196480_28	eggNOG-mapper	1273103.NM10_03141	Bacteriophage lambda head decoration protein D	NA
UHGV-0196480_28	Pfam	PF02924	Bacteriophage lambda head decoration protein D	HDPD
UHGV-0196480_28	Structural annotation	PF02924	NA	NA
UHGV-0196480_29	KOfam	K01358	clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]	NA
UHGV-0196480_29	PHROG	phrog_94	head maturation protease	head and packaging
UHGV-0196480_29	UniRef90	UniRef90_S7J3I6	ATP-dependent Clp protease proteolytic subunit	NA
UHGV-0196480_29	eggNOG-mapper	1273103.NM10_03146	Belongs to the peptidase S14 family	NA
UHGV-0196480_29	Pfam	PF00574	Clp protease	CLP_protease
UHGV-0196480_29	COG	COG0740	ATP-dependent protease ClpP, protease subunit	NA
UHGV-0196480_29	Structural annotation	PF00574, MF_00444, NF011089, COG0740	NA	NA
UHGV-0196480_30	PHROG	phrog_21	portal protein	head and packaging
UHGV-0196480_30	UniRef90	UniRef90_S7HSA9	Phage portal protein	NA
UHGV-0196480_30	eggNOG-mapper	1273103.NM10_03151	Phage portal protein	NA
UHGV-0196480_30	Pfam	PF05136	Phage portal protein, lambda family	Phage_portal_2
UHGV-0196480_30	NCBIFam	TIGR01539.1	phage portal protein	NA
UHGV-0196480_30	COG	COG5511	Phage capsid protein	NA
UHGV-0196480_30	Structural annotation	PF05136, MF_04135, TIGR01539, COG5511	NA	NA
UHGV-0196480_31	PHROG	phrog_20934	NA	unknown function
UHGV-0196480_31	Structural annotation	PF19645	NA	NA
UHGV-0196480_32	KOfam	K21512	gpA; terminase, large subunit [EC:3.1.21.4]	NA
UHGV-0196480_32	PHROG	phrog_15	terminase large subunit	head and packaging
UHGV-0196480_32	UniRef90	UniRef90_S7HS25	Phage terminase large subunit (GpA)	NA
UHGV-0196480_32	eggNOG-mapper	1273103.NM10_03161	Phage terminase large subunit (GpA)	NA
UHGV-0196480_32	Pfam	PF05876	Phage terminase large subunit gpA, ATPase domain	GpA_ATPase
UHGV-0196480_32	Pfam	PF20454	Terminase large subunit gpA, endonuclease domain	GpA_nuclease
UHGV-0196480_32	COG	COG5525	Phage terminase, large subunit GpA	NA
UHGV-0196480_32	HAMAP	MF_04144	Terminase, large subunit	NA
UHGV-0196480_32	Structural annotation	PF05876, PF20454, MF_04144, TIGR01547, COG5525	NA	NA
UHGV-0196480_33	KOfam	K22014	Nu1, Noh; terminase small subunit / prophage DNA-packing protein	NA
UHGV-0196480_33	PHROG	phrog_57	terminase small subunit	head and packaging
UHGV-0196480_33	UniRef90	UniRef90_A0A840PJQ8	Phage terminase Nu1 subunit (DNA packaging protein)	NA
UHGV-0196480_33	eggNOG-mapper	1273103.NM10_03166	NA	NA
UHGV-0196480_33	COG	COG4220	Phage DNA packaging protein, Nu1 subunit of terminase	NA
UHGV-0196480_33	Structural annotation	PF07471, NF040990, COG4220	NA	NA
UHGV-0196480_34	PHROG	phrog_36	transcriptional regulator	transcription regulation
UHGV-0196480_34	UniRef90	UniRef90_UPI0008EE302B	NA	NA
UHGV-0196480_34	eggNOG-mapper	1111454.HMPREF1250_0009	NA	NA
UHGV-0196480_34	Pfam	PF07374	NA	DUF1492
UHGV-0196480_34	Structural annotation	PF07374, TIGR02984, COG2739	NA	NA
UHGV-0196480_35	PHROG	phrog_37395	NA	unknown function
UHGV-0196480_37	PHROG	phrog_1682	RusA-like Holliday junction resolvase	DNA, RNA and nucleotide metabolism
UHGV-0196480_37	UniRef90	UniRef90_UPI000930BD90	RusA family crossover junction endodeoxyribonuclease	NA
UHGV-0196480_37	eggNOG-mapper	1120985.AUMI01000019_gene2247	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC	NA
UHGV-0196480_37	COG	COG4570	Holliday junction resolvase RusA (prophage-encoded endonuclease)	NA
UHGV-0196480_37	Structural annotation	PF19595, NF007305, COG4570	NA	NA
UHGV-0196480_38	PHROG	phrog_3584	replication initiation protein	DNA, RNA and nucleotide metabolism
UHGV-0196480_38	UniRef90	UniRef90_I2E8X7	Gp31	NA
UHGV-0196480_38	eggNOG-mapper	1064535.MELS_1085	NA	NA
UHGV-0196480_38	Structural annotation	PF21578, NF033538	NA	NA
UHGV-0196480_39	PHROG	phrog_11947	NA	unknown function
UHGV-0196480_41	KOfam	K01520	dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23]	NA
UHGV-0196480_41	PHROG	phrog_135	dUTPase	DNA, RNA and nucleotide metabolism
UHGV-0196480_41	UniRef90	UniRef90_A0A2S0MAB6	dUTP diphosphatase	NA
UHGV-0196480_41	eggNOG-mapper	706434.HMPREF9429_00398	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	NA
UHGV-0196480_41	Pfam	PF00692	dUTPase	dUTPase
UHGV-0196480_41	NCBIFam	TIGR00576.1	dUTP diphosphatase	NA
UHGV-0196480_41	COG	COG0756	dUTP pyrophosphatase (dUTPase)	NA
UHGV-0196480_41	Structural annotation	PF00692, MF_00116, TIGR00576, COG0756	NA	NA
UHGV-0196480_42	KOfam	K03111	ssb; single-strand DNA-binding protein	NA
UHGV-0196480_42	PHROG	phrog_44	single strand DNA binding protein	DNA, RNA and nucleotide metabolism
UHGV-0196480_42	UniRef90	UniRef90_UPI0013B408A0	single-stranded DNA-binding protein	NA
UHGV-0196480_42	eggNOG-mapper	1123371.ATXH01000015_gene1651	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	NA
UHGV-0196480_42	Pfam	PF00436	Single-strand binding protein family	SSB
UHGV-0196480_42	NCBIFam	TIGR00621.2	single-stranded DNA-binding protein	NA
UHGV-0196480_42	COG	COG0629	Single-stranded DNA-binding protein	NA
UHGV-0196480_42	HAMAP	MF_00984	Single-stranded DNA-binding protein	NA
UHGV-0196480_42	Structural annotation	PF00436, MF_00984, NF005406, COG0629	NA	NA
UHGV-0196480_45	PHROG	phrog_236	nucleotide kinase	other
UHGV-0196480_45	UniRef90	UniRef90_UPI001F0F7AF9	NA	NA
UHGV-0196480_45	eggNOG-mapper	706434.HMPREF9429_00388	NA	NA
UHGV-0196480_45	Pfam	PF11753	NA	DUF3310
UHGV-0196480_45	Structural annotation	PF11753	NA	NA
UHGV-0196480_46	PHROG	phrog_15609	NA	unknown function
UHGV-0196480_46	UniRef90	UniRef90_UPI00073F64A5	NA	NA
UHGV-0196480_46	eggNOG-mapper	1232428.CAVO010000003_gene1018	NA	NA
UHGV-0196480_46	Pfam	PF11300	NA	DUF3102
UHGV-0196480_46	COG	COG0188	DNA gyrase/topoisomerase IV, subunit A	NA
UHGV-0196480_46	Structural annotation	PF11300, NF038070	NA	NA
UHGV-0196480_47	PHROG	phrog_8470	NA	unknown function
UHGV-0196480_47	UniRef90	UniRef90_UPI00073F3B84	PcfJ domain-containing protein	NA
UHGV-0196480_47	eggNOG-mapper	717606.PaecuDRAFT_3105	PcfJ-like protein	NA
UHGV-0196480_47	Pfam	PF14284	PcfJ-like protein	PcfJ
UHGV-0196480_48	Structural annotation	PF14058	NA	NA
UHGV-0196480_51	eggNOG-mapper	1064535.MELS_1077	transposase activity	NA
UHGV-0196480_51	COG	COG4220	Phage DNA packaging protein, Nu1 subunit of terminase	NA
UHGV-0196480_52	PHROG	phrog_1672	NA	unknown function
UHGV-0196480_52	UniRef90	UniRef90_S7HT72	NA	NA
UHGV-0196480_52	eggNOG-mapper	1443122.Z958_05695	NA	NA
UHGV-0196480_53	PHROG	phrog_9842	NA	unknown function
UHGV-0196480_53	UniRef90	UniRef90_UPI0018CF3F8F	NA	NA
UHGV-0196480_53	eggNOG-mapper	935837.JAEK01000054_gene1482	NA	NA
UHGV-0196480_53	Pfam	PF10386	NA	DUF2441
UHGV-0196480_53	Structural annotation	PF10386, NF033144	NA	NA
UHGV-0196480_57	PHROG	phrog_25045	NA	unknown function
UHGV-0196480_57	UniRef90	UniRef90_UPI001D005F74	LysM peptidoglycan-binding domain-containing protein	NA
UHGV-0196480_57	eggNOG-mapper	1064535.MELS_1078	LysM domain	NA
UHGV-0196480_57	Pfam	PF01476	LysM domain	LysM
UHGV-0196480_57	COG	COG1388	LysM repeat	NA
UHGV-0196480_57	Structural annotation	PF01476, MF_02014, NF010723, COG1388	NA	NA
UHGV-0196480_59	PHROG	phrog_9842	NA	unknown function
UHGV-0196480_59	UniRef90	UniRef90_UPI0018C7739B	NA	NA
UHGV-0196480_59	eggNOG-mapper	935837.JAEK01000054_gene1482	NA	NA
UHGV-0196480_59	Pfam	PF10386	NA	DUF2441
UHGV-0196480_59	Structural annotation	PF10386, NF033144	NA	NA
UHGV-0196480_64	KOfam	K07729	K07729; putative transcriptional regulator	NA
UHGV-0196480_64	PHROG	phrog_3	transcriptional repressor	transcription regulation
UHGV-0196480_64	UniRef90	UniRef90_A0A414NZT5	XRE family transcriptional regulator	NA
UHGV-0196480_64	eggNOG-mapper	1273103.NM10_01224	sequence-specific DNA binding	NA
UHGV-0196480_64	Pfam	PF01381	Helix-turn-helix	HTH_3
UHGV-0196480_64	COG	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	NA
UHGV-0196480_64	Structural annotation	PF01381, NF041951, COG1476	NA	NA
UHGV-0196480_65	KOfam	K01356	lexA; repressor LexA [EC:3.4.21.88]	NA
UHGV-0196480_65	PHROG	phrog_4	transcriptional repressor	transcription regulation
UHGV-0196480_65	UniRef90	UniRef90_A0A2S0M7Z3	XRE family transcriptional regulator	NA
UHGV-0196480_65	eggNOG-mapper	1064535.MELS_1071	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	NA
UHGV-0196480_65	PADLOC	retron_type_VI_hth_cluster2_1	NA	Retron
UHGV-0196480_65	Pfam	PF01381	Helix-turn-helix	HTH_3
UHGV-0196480_65	Pfam	PF00717	Peptidase S24-like	Peptidase_S24
UHGV-0196480_65	COG	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	NA
UHGV-0196480_65	Structural annotation	PF01381, PF00717, MF_00015, NF041951, COG1396	NA	NA
UHGV-0196480_66	KOfam	K14623	dinD; DNA-damage-inducible protein D	NA
UHGV-0196480_66	PHROG	phrog_8036	NA	unknown function
UHGV-0196480_66	UniRef90	UniRef90_A0A2S0M7T2	Damage-inducible protein D	NA
UHGV-0196480_66	eggNOG-mapper	1131451.O1K_18831	BRO family, N-terminal domain	NA
UHGV-0196480_66	PADLOC	Specificity_I_00032	Type I specificity subunit	RM
UHGV-0196480_66	Pfam	PF02498	BRO family, N-terminal domain	Bro-N
UHGV-0196480_66	COG	COG3617	Prophage antirepressor	NA
UHGV-0196480_66	Structural annotation	PF09669, NF008573, COG3617	NA	NA

All genomes

Genome	vOTU repr.	Length	GC content	CheckV completeness	geNomad score
UHGV-0196480	Yes	46,995 bps	45.87%	99.23%	0.9728
UHGV-0176138	No	24,611 bps	44.99%	52.13%	0.9791
UHGV-1788564	No	16,607 bps	48.31%	35.03%	0.9769
UHGV-1706543	No	10,680 bps	47.01%	22.73%	0.9815