| UHGV-1500123_4 | KOfam | K14059 | int; integrase | NA |
| UHGV-1500123_4 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-1500123_4 | UniRef90 | UniRef90_A0A373XME4 | Site-specific integrase | NA |
| UHGV-1500123_4 | eggNOG-mapper | 428125.CLOLEP_02743 | Belongs to the 'phage' integrase family | NA |
| UHGV-1500123_4 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-1500123_4 | COG | COG4974 | Site-specific recombinase XerD | NA |
| UHGV-1500123_4 | Structural annotation | PF00589, PF14659, MF_02055, TIGR02224, COG4974 | NA | NA |
| UHGV-1500123_5 | UniRef90 | UniRef90_A0A374DTF3 | NA | NA |
| UHGV-1500123_6 | PHROG | phrog_1914 | NA | unknown function |
| UHGV-1500123_6 | UniRef90 | UniRef90_A0A373XNL4 | ImmA/IrrE family metallo-endopeptidase | NA |
| UHGV-1500123_6 | eggNOG-mapper | 1160721.RBI_I01604 | NA | NA |
| UHGV-1500123_6 | Pfam | PF06114 | IrrE N-terminal-like domain | Peptidase_M78 |
| UHGV-1500123_6 | COG | COG2856 | Zn-dependent peptidase ImmA, M78 family | NA |
| UHGV-1500123_6 | Structural annotation | PF06114, COG2856 | NA | NA |
| UHGV-1500123_7 | PHROG | phrog_2967 | transcriptional regulator | transcription regulation |
| UHGV-1500123_7 | UniRef90 | UniRef90_A0A374ND72 | Transcriptional regulator | NA |
| UHGV-1500123_7 | eggNOG-mapper | 457412.RSAG_00795 | sequence-specific DNA binding | NA |
| UHGV-1500123_7 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1500123_7 | Structural annotation | PF13560, MF_00535, NF007257, COG3655 | NA | NA |
| UHGV-1500123_8 | UniRef90 | UniRef90_A0A374N1V0 | NA | NA |
| UHGV-1500123_8 | eggNOG-mapper | 171693.BN988_01635 | NA | NA |
| UHGV-1500123_8 | Pfam | PF05339 | NA | DUF739 |
| UHGV-1500123_8 | COG | COG3655 | DNA-binding transcriptional regulator, XRE family | NA |
| UHGV-1500123_8 | Structural annotation | PF05339, NF002773, COG1476 | NA | NA |
| UHGV-1500123_9 | UniRef90 | UniRef90_A0A1C5RYU8 | Restriction alleviation protein, Lar family | NA |
| UHGV-1500123_9 | Structural annotation | NF007260 | NA | NA |
| UHGV-1500123_11 | UniRef90 | UniRef90_A0A2N0ULS1 | YozE_SAM_like domain-containing protein | NA |
| UHGV-1500123_11 | Pfam | PF06855 | YozE SAM-like fold | YozE_SAM_like |
| UHGV-1500123_12 | KOfam | K15773 | hipB; HTH-type transcriptional regulator / antitoxin HipB | NA |
| UHGV-1500123_12 | PHROG | phrog_3 | transcriptional repressor | transcription regulation |
| UHGV-1500123_12 | UniRef90 | UniRef90_A0A374N3U7 | XRE family transcriptional regulator | NA |
| UHGV-1500123_12 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1500123_12 | COG | COG1974 | SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) | NA |
| UHGV-1500123_12 | Structural annotation | PF01381, NF041951, COG1396 | NA | NA |
| UHGV-1500123_14 | UniRef90 | UniRef90_A0A2N0ULT9 | DNA binding domain, excisionase family | NA |
| UHGV-1500123_14 | eggNOG-mapper | 1283300.ATXB01000001_gene1737 | DNA excision | NA |
| UHGV-1500123_14 | Pfam | PF12728 | Helix-turn-helix domain | HTH_17 |
| UHGV-1500123_14 | NCBIFam | TIGR01764.1 | excisionase family DNA-binding protein | NA |
| UHGV-1500123_14 | COG | COG3311 | DNA-binding transcriptional regulator AlpA | NA |
| UHGV-1500123_14 | Structural annotation | PF12728, NF040990, COG3311 | NA | NA |
| UHGV-1500123_17 | PHROG | phrog_8470 | NA | unknown function |
| UHGV-1500123_17 | UniRef90 | UniRef90_UPI0018E45158 | PcfJ domain-containing protein | NA |
| UHGV-1500123_17 | eggNOG-mapper | 641112.ACOK01000073_gene2870 | PcfJ-like protein | NA |
| UHGV-1500123_17 | Pfam | PF14284 | PcfJ-like protein | PcfJ |
| UHGV-1500123_17 | Structural annotation | PF14284 | NA | NA |
| UHGV-1500123_18 | PHROG | phrog_15609 | NA | unknown function |
| UHGV-1500123_18 | UniRef90 | UniRef90_A0A373VML2 | NA | NA |
| UHGV-1500123_18 | eggNOG-mapper | 641112.ACOK01000073_gene2872 | NA | NA |
| UHGV-1500123_18 | Structural annotation | PF11300, NF033725 | NA | NA |
| UHGV-1500123_19 | PHROG | phrog_253 | Mu Gam-like end protection | DNA, RNA and nucleotide metabolism |
| UHGV-1500123_19 | UniRef90 | UniRef90_UPI0019171ADA | siphovirus Gp157 family protein | NA |
| UHGV-1500123_19 | eggNOG-mapper | 1027396.LMOSA_21290 | Siphovirus Gp157 | NA |
| UHGV-1500123_19 | Pfam | PF05565 | Siphovirus Gp157 | Sipho_Gp157 |
| UHGV-1500123_19 | Structural annotation | PF05565 | NA | NA |
| UHGV-1500123_20 | PHROG | phrog_2872 | Sak4-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-1500123_20 | UniRef90 | UniRef90_UPI001A9B3ECC | AAA family ATPase | NA |
| UHGV-1500123_20 | eggNOG-mapper | 754027.HMPREF9554_00709 | NA | NA |
| UHGV-1500123_20 | Pfam | PF13479 | AAA domain | AAA_24 |
| UHGV-1500123_20 | Structural annotation | PF13479, MF_00350, TIGR01618, COG0468 | NA | NA |
| UHGV-1500123_21 | KOfam | K19789 | radD; DNA repair protein RadD | NA |
| UHGV-1500123_21 | PHROG | phrog_16 | DNA helicase | DNA, RNA and nucleotide metabolism |
| UHGV-1500123_21 | UniRef90 | UniRef90_A0A374N1T8 | Helicase | NA |
| UHGV-1500123_21 | eggNOG-mapper | 1410670.JHXF01000015_gene2270 | helicase | NA |
| UHGV-1500123_21 | PADLOC | mREase_IV_00005 | Type IV methyl-directed restriction enzyme | RM |
| UHGV-1500123_21 | Pfam | PF04851 | Type III restriction enzyme, res subunit | ResIII |
| UHGV-1500123_21 | Pfam | PF00271 | Helicase conserved C-terminal domain | Helicase_C |
| UHGV-1500123_21 | COG | COG1061 | Superfamily II DNA or RNA helicase | NA |
| UHGV-1500123_21 | Structural annotation | PF04851, PF00271, MF_01489, TIGR04095, COG1061 | NA | NA |
| UHGV-1500123_22 | PHROG | phrog_5702 | Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-1500123_22 | UniRef90 | UniRef90_A0A374N329 | VRR-NUC domain-containing protein | NA |
| UHGV-1500123_22 | eggNOG-mapper | 1410670.JHXF01000015_gene2271 | VRR_NUC | NA |
| UHGV-1500123_22 | Pfam | PF08774 | VRR-NUC domain | VRR_NUC |
| UHGV-1500123_22 | Structural annotation | PF01870, MF_00130, NF002581, COG1591 | NA | NA |
| UHGV-1500123_23 | PHROG | phrog_378 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-1500123_23 | UniRef90 | UniRef90_A0A374ND86 | NA | NA |
| UHGV-1500123_23 | eggNOG-mapper | 1410670.JHXF01000015_gene2272 | NA | NA |
| UHGV-1500123_23 | Pfam | PF05037 | NA | DUF669 |
| UHGV-1500123_23 | Structural annotation | PF05037, NF004948 | NA | NA |
| UHGV-1500123_24 | KOfam | K06919 | K06919; putative DNA primase/helicase | NA |
| UHGV-1500123_24 | PHROG | phrog_1829 | DNA primase | DNA, RNA and nucleotide metabolism |
| UHGV-1500123_24 | UniRef90 | UniRef90_A0A2N0ULU7 | SF3 helicase domain-containing protein | NA |
| UHGV-1500123_24 | eggNOG-mapper | 1410670.JHXF01000015_gene2274 | Phage plasmid primase, P4 family | NA |
| UHGV-1500123_24 | Pfam | PF08706 | D5 N terminal like | D5_N |
| UHGV-1500123_24 | Pfam | PF19263 | NA | DUF5906 |
| UHGV-1500123_24 | Pfam | PF03288 | Poxvirus D5 protein-like | Pox_D5 |
| UHGV-1500123_24 | NCBIFam | TIGR01613.1 | phage/plasmid primase, P4 family | NA |
| UHGV-1500123_24 | COG | COG3378 | DNA primase, phage- or plasmid-associated | NA |
| UHGV-1500123_24 | Structural annotation | PF08706, PF05272, PF02257, MF_04000, NF011296, COG3378, COG4983 | NA | NA |
| UHGV-1500123_27 | PHROG | phrog_10714 | NA | unknown function |
| UHGV-1500123_27 | eggNOG-mapper | 742723.HMPREF9477_00922 | NA | NA |
| UHGV-1500123_28 | UniRef90 | UniRef90_UPI000E4DC4DA | helix-turn-helix domain-containing protein | NA |
| UHGV-1500123_28 | Structural annotation | PF15597 | NA | NA |
| UHGV-1500123_31 | PHROG | phrog_599 | Lar-like restriction alleviation protein | moron, auxiliary metabolic gene and host takeover |
| UHGV-1500123_31 | Pfam | PF14354 | Restriction alleviation protein Lar | Lar_restr_allev |
| UHGV-1500123_31 | dbAPIS | APIS033 | Lar is functionally similar to RaI, is able to alleviate restriction and enhance modification by EcoKI. And the nucleotide sequences of their genes share 47% identity, indicating a common origin. | NA |
| UHGV-1500123_32 | Pfam | PF13240 | zinc-ribbon domain | zinc_ribbon_2 |
| UHGV-1500123_35 | Structural annotation | PF02796, COG2771 | NA | NA |
| UHGV-1500123_36 | PHROG | phrog_119 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1500123_36 | UniRef90 | UniRef90_A0A374N9T6 | HNH endonuclease | NA |
| UHGV-1500123_36 | eggNOG-mapper | 1235793.C809_01915 | HNH endonuclease | NA |
| UHGV-1500123_36 | COG | COG1403 | 5-methylcytosine-specific restriction endonuclease McrA | NA |
| UHGV-1500123_37 | PHROG | phrog_1066 | NA | unknown function |
| UHGV-1500123_37 | UniRef90 | UniRef90_A0A0D0SQQ8 | NA | NA |
| UHGV-1500123_37 | eggNOG-mapper | 1203606.HMPREF1526_00982 | NA | NA |
| UHGV-1500123_38 | PHROG | phrog_9 | terminase large subunit | head and packaging |
| UHGV-1500123_38 | UniRef90 | UniRef90_A0A374NB45 | Terminase large subunit | NA |
| UHGV-1500123_38 | eggNOG-mapper | 1235793.C809_01917 | Phage Terminase | NA |
| UHGV-1500123_38 | Pfam | PF03354 | Terminase large subunit, ATPase domain | TerL_ATPase |
| UHGV-1500123_38 | Pfam | PF20441 | Terminase large subunit, endonuclease domain | TerL_nuclease |
| UHGV-1500123_38 | COG | COG4626 | Phage terminase-like protein, large subunit, contains N-terminal HTH domain | NA |
| UHGV-1500123_38 | Structural annotation | PF20441, PF03354, MF_04145, TIGR01547, COG4626 | NA | NA |
| UHGV-1500123_39 | PHROG | phrog_12 | portal protein | head and packaging |
| UHGV-1500123_39 | UniRef90 | UniRef90_A0A374NAE1 | Phage portal protein | NA |
| UHGV-1500123_39 | eggNOG-mapper | 626523.GCWU000342_01027 | Portal protein | NA |
| UHGV-1500123_39 | Pfam | PF04860 | Phage portal protein | Phage_portal |
| UHGV-1500123_39 | COG | COG4695 | Phage portal protein BeeE | NA |
| UHGV-1500123_39 | Structural annotation | PF04860, MF_04135, TIGR01537, COG4695 | NA | NA |
| UHGV-1500123_40 | KOfam | K01358 | clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] | NA |
| UHGV-1500123_40 | PHROG | phrog_94 | head maturation protease | head and packaging |
| UHGV-1500123_40 | UniRef90 | UniRef90_A0A374NBM3 | ATP-dependent Clp protease proteolytic subunit | NA |
| UHGV-1500123_40 | eggNOG-mapper | 1203606.HMPREF1526_00979 | Belongs to the peptidase S14 family | NA |
| UHGV-1500123_40 | Pfam | PF00574 | Clp protease | CLP_protease |
| UHGV-1500123_40 | COG | COG0740 | ATP-dependent protease ClpP, protease subunit | NA |
| UHGV-1500123_40 | Structural annotation | PF00574, MF_00444, NF011090, COG0740 | NA | NA |
| UHGV-1500123_41 | PHROG | phrog_10 | major head protein | head and packaging |
| UHGV-1500123_41 | UniRef90 | UniRef90_A0A374N9V9 | Phage major capsid protein | NA |
| UHGV-1500123_41 | eggNOG-mapper | 1280689.AUJC01000011_gene1521 | Phage major capsid protein, HK97 family | NA |
| UHGV-1500123_41 | Pfam | PF05065 | Phage capsid family | Phage_capsid |
| UHGV-1500123_41 | NCBIFam | TIGR01554.2 | phage major capsid protein | NA |
| UHGV-1500123_41 | COG | COG4653 | Predicted phage phi-C31 gp36 major capsid-like protein | NA |
| UHGV-1500123_41 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-1500123_42 | PHROG | phrog_5223 | neck protein | connector |
| UHGV-1500123_42 | eggNOG-mapper | 931626.Awo_c31020 | NA | NA |
| UHGV-1500123_42 | NCBIFam | TIGR01560.2 | head-tail connector protein | NA |
| UHGV-1500123_42 | Structural annotation | TIGR01560 | NA | NA |
| UHGV-1500123_43 | PHROG | phrog_1951 | head-tail adaptor | connector |
| UHGV-1500123_43 | UniRef90 | UniRef90_A0A374MZF9 | Phage head-tail adapter protein | NA |
| UHGV-1500123_43 | eggNOG-mapper | 1414720.CBYM010000040_gene1649 | head-tail adaptor | NA |
| UHGV-1500123_43 | COG | COG5614 | Phage head-tail adaptor | NA |
| UHGV-1500123_43 | Structural annotation | PF05521, TIGR01563, COG5614 | NA | NA |
| UHGV-1500123_44 | UniRef90 | UniRef90_UPI001A9B6FBF | HK97 gp10 family phage protein | NA |
| UHGV-1500123_44 | eggNOG-mapper | 1414720.CBYM010000040_gene1650 | NA | NA |
| UHGV-1500123_44 | Structural annotation | TIGR01725 | NA | NA |
| UHGV-1500123_45 | Structural annotation | PF12691 | NA | NA |
| UHGV-1500123_46 | PHROG | phrog_885 | major tail protein | tail |
| UHGV-1500123_46 | UniRef90 | UniRef90_Q894J4 | Conserved protein | NA |
| UHGV-1500123_46 | eggNOG-mapper | 1321814.HMPREF9089_00935 | NA | NA |
| UHGV-1500123_46 | Structural annotation | PF06488, TIGR01603, COG5437 | NA | NA |
| UHGV-1500123_47 | PHROG | phrog_1021 | NA | unknown function |
| UHGV-1500123_47 | eggNOG-mapper | 1321778.HMPREF1982_03556 | NA | NA |
| UHGV-1500123_49 | PHROG | phrog_23464 | NA | unknown function |
| UHGV-1500123_49 | eggNOG-mapper | 1378168.N510_03078 | Tail tape measure protein, TP901 family | NA |
| UHGV-1500123_49 | COG | COG5280 | Phage-related minor tail protein | NA |
| UHGV-1500123_49 | Structural annotation | COG3941 | NA | NA |
| UHGV-1500123_50 | UniRef90 | UniRef90_A0A1G5CPA2 | Phage-related protein | NA |
| UHGV-1500123_50 | eggNOG-mapper | 1246.JMEA01000006_gene51 | phage tail | NA |
| UHGV-1500123_50 | COG | COG4722 | Phage-related protein YomH | NA |
| UHGV-1500123_50 | Structural annotation | PF20195, TIGR01633, COG4722 | NA | NA |
| UHGV-1500123_51 | PHROG | phrog_1067 | minor head protein | head and packaging |
| UHGV-1500123_51 | UniRef90 | UniRef90_A0A348ZBV6 | Prophage_tail domain-containing protein | NA |
| UHGV-1500123_51 | eggNOG-mapper | 1160721.RBI_I01574 | Prophage endopeptidase tail | NA |
| UHGV-1500123_51 | Pfam | PF06605 | Prophage endopeptidase tail | Prophage_tail |
| UHGV-1500123_51 | NCBIFam | TIGR01665.1 | phage tail spike protein | NA |
| UHGV-1500123_51 | COG | COG4926 | Phage-related protein | NA |
| UHGV-1500123_51 | Structural annotation | PF14594, TIGR01665, COG4926 | NA | NA |
| UHGV-1500123_52 | UniRef90 | UniRef90_A0A373XLZ6 | NA | NA |
| UHGV-1500123_52 | Pfam | PF10651 | BppU N-terminal domain | BppU_N |
| UHGV-1500123_52 | Structural annotation | PF10651, PF15432, PF08931, TIGR03711 | NA | NA |
| UHGV-1500123_54 | PHROG | phrog_199 | holin | lysis |
| UHGV-1500123_54 | UniRef90 | UniRef90_A0A2N0ULW7 | Holin | NA |
| UHGV-1500123_54 | eggNOG-mapper | 1160721.RBI_I01565 | Bacteriophage holin family | NA |
| UHGV-1500123_54 | Pfam | PF05105 | Bacteriophage holin family | Phage_holin_4_1 |
| UHGV-1500123_54 | NCBIFam | TIGR01593.1 | toxin secretion/phage lysis holin | NA |
| UHGV-1500123_54 | COG | COG4824 | Phage-related holin (Lysis protein) | NA |
| UHGV-1500123_54 | Structural annotation | PF05105, TIGR01593, COG4824 | NA | NA |
| UHGV-1500123_55 | KOfam | K01447 | xlyAB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | NA |
| UHGV-1500123_55 | PHROG | phrog_20388 | endolysin | lysis |
| UHGV-1500123_55 | UniRef90 | UniRef90_A0A374N1L8 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-1500123_55 | eggNOG-mapper | 1203606.HMPREF1526_00253 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-1500123_55 | Pfam | PF01510 | N-acetylmuramoyl-L-alanine amidase | Amidase_2 |
| UHGV-1500123_55 | Pfam | PF01471 | Putative peptidoglycan binding domain | PG_binding_1 |
| UHGV-1500123_55 | COG | COG0860 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-1500123_55 | Structural annotation | PF01510, PF01476, PF15591, MF_02014, MF_04111, MF_01354, NF008758, NF010723, TIGR00405, COG3023, COG5004, COG2139 | NA | NA |
| UHGV-1500123_56 | KOfam | K14059 | int; integrase | NA |
| UHGV-1500123_56 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-1500123_56 | UniRef90 | UniRef90_A0A125V7D3 | Integrase | NA |
| UHGV-1500123_56 | eggNOG-mapper | 1121115.AXVN01000026_gene1022 | NA | NA |
| UHGV-1500123_56 | Pfam | PF02920 | DNA binding domain of tn916 integrase | Integrase_DNA |
| UHGV-1500123_56 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-1500123_56 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-1500123_56 | Structural annotation | PF00589, PF02920, PF14659, MF_01808, TIGR02224, COG4974 | NA | NA |
| UHGV-1500123_57 | PHROG | phrog_16129 | excisionase | integration and excision |
| UHGV-1500123_57 | UniRef90 | UniRef90_A0A416RUE6 | Excisionase | NA |
| UHGV-1500123_57 | eggNOG-mapper | 272563.CD630_10920 | Excisionase from transposon Tn916 | NA |
| UHGV-1500123_57 | Pfam | PF09035 | Excisionase from transposon Tn916 | Tn916-Xis |
| UHGV-1500123_57 | NCBIFam | TIGR01764.1 | excisionase family DNA-binding protein | NA |
| UHGV-1500123_57 | Structural annotation | PF09035, TIGR01764, COG3311 | NA | NA |
| UHGV-1500123_58 | PHROG | phrog_20245 | NA | unknown function |
| UHGV-1500123_58 | UniRef90 | UniRef90_A0A3E5A3X2 | Helix-turn-helix domain-containing protein | NA |
| UHGV-1500123_58 | eggNOG-mapper | 1121115.AXVN01000026_gene1024 | Helix-turn-helix domain | NA |
| UHGV-1500123_58 | Pfam | PF12645 | Helix-turn-helix domain | HTH_16 |
| UHGV-1500123_58 | Structural annotation | PF12645 | NA | NA |
| UHGV-1500123_59 | KOfam | K03088 | rpoE; RNA polymerase sigma-70 factor, ECF subfamily | NA |
| UHGV-1500123_59 | UniRef90 | UniRef90_B0G6W4 | RNA polymerase sigma factor, sigma-70 family | NA |
| UHGV-1500123_59 | eggNOG-mapper | 397287.C807_00017 | Sigma-70, region 4 | NA |
| UHGV-1500123_59 | Pfam | PF08281 | Sigma-70, region 4 | Sigma70_r4_2 |
| UHGV-1500123_59 | NCBIFam | TIGR02937.1 | sigma-70 family RNA polymerase sigma factor | NA |
| UHGV-1500123_59 | COG | COG1595 | DNA-directed RNA polymerase specialized sigma subunit, sigma24 family | NA |
| UHGV-1500123_59 | Structural annotation | PF08281, MF_00245, TIGR02937, COG1595 | NA | NA |