| UHGV-0118282_1 | KOfam | K18843 | hicB; antitoxin HicB | NA |
| UHGV-0118282_1 | PHROG | phrog_33232 | NA | unknown function |
| UHGV-0118282_1 | UniRef90 | UniRef90_R6C298 | HicB family protein | NA |
| UHGV-0118282_1 | eggNOG-mapper | 97138.C820_00752 | HicB family | NA |
| UHGV-0118282_1 | Pfam | PF21748 | UPF0150-like | UPF0150 |
| UHGV-0118282_1 | Pfam | PF05534 | HicB family | HicB |
| UHGV-0118282_1 | COG | COG1598 | Antitoxin component HicB of the HicAB toxin-antitoxin system | NA |
| UHGV-0118282_1 | Structural annotation | PF15919, COG1598, COG4691 | NA | NA |
| UHGV-0118282_3 | KOfam | K22299 | rghR; HTH-type transcriptional regulator, competence development regulator | NA |
| UHGV-0118282_3 | PHROG | phrog_3 | transcriptional repressor | transcription regulation |
| UHGV-0118282_3 | UniRef90 | UniRef90_R5YVI1 | HTH-type transcriptional regulator SinR | NA |
| UHGV-0118282_3 | eggNOG-mapper | 86416.Clopa_3404 | helix-turn-helix | NA |
| UHGV-0118282_3 | PADLOC | retron_type_VI_hth_cluster2_1 | NA | Retron |
| UHGV-0118282_3 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0118282_3 | Pfam | PF09388 | Spo0E like sporulation regulatory protein | SpoOE-like |
| UHGV-0118282_3 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0118282_3 | Structural annotation | PF13443, MF_00535, NF041951, COG3655 | NA | NA |
| UHGV-0118282_5 | KOfam | K01446 | PGRP; peptidoglycan recognition protein | NA |
| UHGV-0118282_5 | PHROG | phrog_1493 | endolysin | lysis |
| UHGV-0118282_5 | UniRef90 | UniRef90_K1TXM5 | N-acetylmuramoyl-L-alanine amidase (Fragment) | NA |
| UHGV-0118282_5 | eggNOG-mapper | 1280698.AUJS01000007_gene1059 | Ami_2 | NA |
| UHGV-0118282_5 | Pfam | PF01510 | N-acetylmuramoyl-L-alanine amidase | Amidase_2 |
| UHGV-0118282_5 | Pfam | PF01471 | Putative peptidoglycan binding domain | PG_binding_1 |
| UHGV-0118282_5 | COG | COG3409 | Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases | NA |
| UHGV-0118282_5 | Structural annotation | PF01510, PF01471, MF_04111, NF008758, COG5632, COG3409 | NA | NA |
| UHGV-0118282_6 | PHROG | phrog_1129 | holin | lysis |
| UHGV-0118282_6 | UniRef90 | UniRef90_A0A1Q6M1T2 | Holin | NA |
| UHGV-0118282_6 | eggNOG-mapper | 1391647.AVSV01000036_gene884 | Phage holin family Hol44, in holin superfamily V | NA |
| UHGV-0118282_6 | Pfam | PF16079 | Phage holin family Hol44, in holin superfamily V | Phage_holin_5_2 |
| UHGV-0118282_6 | Structural annotation | PF06946 | NA | NA |
| UHGV-0118282_7 | eggNOG-mapper | 1235793.C809_03303 | NA | NA |
| UHGV-0118282_9 | Structural annotation | PF17735 | NA | NA |
| UHGV-0118282_11 | UniRef90 | UniRef90_A0A1Q6M1V5 | Fibronectin type-III domain-containing protein | NA |
| UHGV-0118282_11 | Structural annotation | PF05895, MF_00791, NF010681, COG2967 | NA | NA |
| UHGV-0118282_12 | PHROG | phrog_1220 | head protein | head and packaging |
| UHGV-0118282_12 | UniRef90 | UniRef90_A0A239ZA53 | Phage structural protein | NA |
| UHGV-0118282_12 | eggNOG-mapper | 491915.Aflv_0675 | cellulose 1,4-beta-cellobiosidase activity | NA |
| UHGV-0118282_12 | COG | COG5301 | Phage-related tail fiber protein | NA |
| UHGV-0118282_13 | PHROG | phrog_538 | minor tail protein | tail |
| UHGV-0118282_13 | UniRef90 | UniRef90_UPI0006847BDA | siphovirus ReqiPepy6 Gp37-like family protein | NA |
| UHGV-0118282_13 | eggNOG-mapper | 235909.GK0542 | Siphovirus ReqiPepy6 Gp37-like protein | NA |
| UHGV-0118282_13 | Pfam | PF14594 | Siphovirus ReqiPepy6 Gp37-like protein | Sipho_Gp37 |
| UHGV-0118282_13 | Structural annotation | PF14594, TIGR01665, COG4379 | NA | NA |
| UHGV-0118282_14 | PHROG | phrog_33 | distal tail protein Dit | tail |
| UHGV-0118282_14 | UniRef90 | UniRef90_UPI001784C83A | phage tail family protein | NA |
| UHGV-0118282_14 | eggNOG-mapper | 491915.Aflv_0674 | Phage tail protein | NA |
| UHGV-0118282_14 | COG | COG4722 | Phage-related protein YomH | NA |
| UHGV-0118282_14 | Structural annotation | PF05709, PF20753, TIGR01633, COG4722 | NA | NA |
| UHGV-0118282_15 | PHROG | phrog_7078 | NA | unknown function |
| UHGV-0118282_15 | UniRef90 | UniRef90_A0A162MGL3 | PhageMin_Tail domain-containing protein | NA |
| UHGV-0118282_15 | eggNOG-mapper | 1122927.KB895413_gene1615 | phage tail tape measure protein | NA |
| UHGV-0118282_15 | COG | COG5283 | Phage-related tail protein | NA |
| UHGV-0118282_18 | PHROG | phrog_88 | major tail protein | tail |
| UHGV-0118282_18 | NCBIFam | TIGR01603.1 | major tail protein | NA |
| UHGV-0118282_18 | COG | COG5492 | NA | NA |
| UHGV-0118282_18 | Structural annotation | PF06488, TIGR01603, COG5437 | NA | NA |
| UHGV-0118282_19 | PHROG | phrog_78 | tail terminator | connector |
| UHGV-0118282_19 | UniRef90 | UniRef90_A0A7W2AJJ9 | NA | NA |
| UHGV-0118282_19 | eggNOG-mapper | 1329516.JPST01000016_gene402 | NA | NA |
| UHGV-0118282_19 | Structural annotation | PF05657 | NA | NA |
| UHGV-0118282_20 | PHROG | phrog_5 | tail completion or Neck1 protein | connector |
| UHGV-0118282_20 | UniRef90 | UniRef90_A0A4R7KUL9 | HK97 gp10 family phage protein | NA |
| UHGV-0118282_20 | eggNOG-mapper | 1280692.AUJL01000025_gene2076 | Bacteriophage HK97-gp10, putative tail-component | NA |
| UHGV-0118282_20 | Pfam | PF04883 | Bacteriophage HK97-gp10, putative tail-component | HK97-gp10_like |
| UHGV-0118282_20 | NCBIFam | TIGR01725.1 | HK97-gp10 family putative phage morphogenesis protein | NA |
| UHGV-0118282_20 | Structural annotation | PF04883, TIGR01725 | NA | NA |
| UHGV-0118282_22 | PHROG | phrog_132 | head-tail adaptor | connector |
| UHGV-0118282_22 | eggNOG-mapper | 445335.CBN_2985 | Phage gp6-like head-tail connector protein | NA |
| UHGV-0118282_22 | Pfam | PF05135 | Phage gp6-like head-tail connector protein | Phage_connect_1 |
| UHGV-0118282_22 | Structural annotation | PF05135, TIGR01560 | NA | NA |
| UHGV-0118282_23 | PHROG | phrog_10 | major head protein | head and packaging |
| UHGV-0118282_23 | UniRef90 | UniRef90_A0A6N7S5V0 | Phage major capsid protein | NA |
| UHGV-0118282_23 | eggNOG-mapper | 1123250.KB908414_gene2105 | Phage capsid family | NA |
| UHGV-0118282_23 | Pfam | PF05065 | Phage capsid family | Phage_capsid |
| UHGV-0118282_23 | Pfam | PF18316 | S-layer protein SbsC C-terminal domain | S-l_SbsC_C |
| UHGV-0118282_23 | NCBIFam | TIGR01554.2 | phage major capsid protein | NA |
| UHGV-0118282_23 | COG | COG4653 | Predicted phage phi-C31 gp36 major capsid-like protein | NA |
| UHGV-0118282_23 | Structural annotation | PF05065, PF13620, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0118282_24 | PHROG | phrog_194 | head scaffolding protein | head and packaging |
| UHGV-0118282_24 | UniRef90 | UniRef90_UPI0015D4C5E5 | phage scaffolding protein | NA |
| UHGV-0118282_24 | eggNOG-mapper | 1121335.Clst_0391 | Phage minor structural protein GP20 | NA |
| UHGV-0118282_24 | Pfam | PF06810 | Phage minor structural protein GP20 | Phage_GP20 |
| UHGV-0118282_24 | Structural annotation | PF06810 | NA | NA |
| UHGV-0118282_25 | UniRef90 | UniRef90_I7JVE6 | Conserved protein | NA |
| UHGV-0118282_25 | eggNOG-mapper | 1064535.MELS_1696 | NA | NA |
| UHGV-0118282_25 | Structural annotation | PF20111 | NA | NA |
| UHGV-0118282_26 | PHROG | phrog_115 | minor head protein | head and packaging |
| UHGV-0118282_26 | UniRef90 | UniRef90_A0A1M6MYA3 | Phage putative head morphogenesis protein, SPP1 gp7 family | NA |
| UHGV-0118282_26 | eggNOG-mapper | 1294142.CINTURNW_1685 | Phage Mu protein F like protein | NA |
| UHGV-0118282_26 | Pfam | PF04233 | Phage Mu protein F like protein | Phage_Mu_F |
| UHGV-0118282_26 | NCBIFam | TIGR01641.1 | minor capsid protein | NA |
| UHGV-0118282_26 | COG | COG2369 | NA | NA |
| UHGV-0118282_26 | Structural annotation | PF04233, TIGR01641, COG2369 | NA | NA |
| UHGV-0118282_27 | PHROG | phrog_64 | portal protein | head and packaging |
| UHGV-0118282_27 | UniRef90 | UniRef90_UPI000C078B3E | phage portal protein | NA |
| UHGV-0118282_27 | eggNOG-mapper | 1522092.A0A090DBP3_9CAUD | Phage portal protein, SPP1 Gp6-like | NA |
| UHGV-0118282_27 | Pfam | PF05133 | Phage portal protein, SPP1 Gp6-like | Phage_prot_Gp6 |
| UHGV-0118282_27 | NCBIFam | TIGR01538.1 | phage portal protein | NA |
| UHGV-0118282_27 | Structural annotation | PF05133, MF_04120, TIGR01538, COG5511 | NA | NA |
| UHGV-0118282_28 | PHROG | phrog_5902 | NA | unknown function |
| UHGV-0118282_28 | UniRef90 | UniRef90_A0A0M2NI11 | Putative terminase B protein | NA |
| UHGV-0118282_28 | eggNOG-mapper | 1226322.HMPREF1545_03544 | A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD | NA |
| UHGV-0118282_28 | COG | COG0507 | ATPase/5'-3' helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) | NA |
| UHGV-0118282_28 | Structural annotation | PF20441, MF_04148, TIGR01547, COG4373 | NA | NA |
| UHGV-0118282_29 | PHROG | phrog_5902 | NA | unknown function |
| UHGV-0118282_29 | UniRef90 | UniRef90_UPI000B20B41E | DEAD/DEAH box helicase family protein | NA |
| UHGV-0118282_29 | eggNOG-mapper | 411459.RUMOBE_01049 | A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD | NA |
| UHGV-0118282_29 | COG | COG0507 | ATPase/5'-3' helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) | NA |
| UHGV-0118282_29 | Structural annotation | PF03354, MF_04148, NF007827, COG5410 | NA | NA |
| UHGV-0118282_34 | Structural annotation | PF05263, TIGR01636 | NA | NA |
| UHGV-0118282_42 | PHROG | phrog_23747 | NA | unknown function |
| UHGV-0118282_42 | UniRef90 | UniRef90_A0A7Y9A9N6 | Magnesium-transporting ATPase (P-type) | NA |
| UHGV-0118282_42 | Structural annotation | NF040944 | NA | NA |
| UHGV-0118282_46 | PHROG | phrog_23490 | NA | unknown function |
| UHGV-0118282_51 | KOfam | K01160 | rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10] | NA |
| UHGV-0118282_51 | PHROG | phrog_1682 | RusA-like Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-0118282_51 | UniRef90 | UniRef90_R7FGZ0 | Gp63 | NA |
| UHGV-0118282_51 | eggNOG-mapper | 428125.CLOLEP_01819 | Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC | NA |
| UHGV-0118282_51 | COG | COG4570 | Holliday junction resolvase RusA (prophage-encoded endonuclease) | NA |
| UHGV-0118282_51 | Structural annotation | PF19595, NF007305, COG4570 | NA | NA |
| UHGV-0118282_52 | PHROG | phrog_1123 | NA | unknown function |
| UHGV-0118282_52 | UniRef90 | UniRef90_A0A7U3NJT7 | Putative transcriptional regulator | NA |
| UHGV-0118282_52 | eggNOG-mapper | 445972.ANACOL_03346 | NA | NA |
| UHGV-0118282_52 | Structural annotation | PF03551, TIGR02719, COG1695 | NA | NA |
| UHGV-0118282_55 | KOfam | K02314 | dnaB; replicative DNA helicase [EC:5.6.2.3] | NA |
| UHGV-0118282_55 | PHROG | phrog_19 | DnaB-like replicative helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0118282_55 | UniRef90 | UniRef90_R5ZPV6 | DNA helicase | NA |
| UHGV-0118282_55 | eggNOG-mapper | 796940.HMPREF9628_01758 | Participates in initiation and elongation during chromosome replication | NA |
| UHGV-0118282_55 | Pfam | PF00772 | DnaB-like helicase N terminal domain | DnaB |
| UHGV-0118282_55 | Pfam | PF03796 | DnaB-like helicase C terminal domain | DnaB_C |
| UHGV-0118282_55 | COG | COG0305 | Replicative DNA helicase | NA |
| UHGV-0118282_55 | Structural annotation | PF03796, PF00772, MF_04155, TIGR00665, COG0305 | NA | NA |
| UHGV-0118282_56 | PHROG | phrog_186 | DnaD-like helicase loader | DNA, RNA and nucleotide metabolism |
| UHGV-0118282_56 | UniRef90 | UniRef90_A0A2K9P1I8 | DnaD domain protein | NA |
| UHGV-0118282_56 | eggNOG-mapper | 1139219.I569_00217 | Replication initiation and membrane attachment | NA |
| UHGV-0118282_56 | COG | COG3935 | DNA replication protein DnaD | NA |
| UHGV-0118282_56 | Structural annotation | PF04492, MF_01911, TIGR01610, COG3355 | NA | NA |
| UHGV-0118282_57 | PHROG | phrog_7566 | NA | unknown function |
| UHGV-0118282_57 | eggNOG-mapper | 1304866.K413DRAFT_1198 | NA | NA |
| UHGV-0118282_58 | PHROG | phrog_1389 | NA | unknown function |
| UHGV-0118282_58 | eggNOG-mapper | 1280692.AUJL01000025_gene2094 | NA | NA |
| UHGV-0118282_58 | Structural annotation | PF11056, TIGR04376, COG1842 | NA | NA |
| UHGV-0118282_59 | PHROG | phrog_18107 | NA | unknown function |
| UHGV-0118282_59 | UniRef90 | UniRef90_R6I207 | PF05037 family protein | NA |
| UHGV-0118282_59 | eggNOG-mapper | 1449050.JNLE01000003_gene3912 | NA | NA |
| UHGV-0118282_59 | Structural annotation | PF05037 | NA | NA |
| UHGV-0118282_60 | PHROG | phrog_2872 | Sak4-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0118282_60 | UniRef90 | UniRef90_UPI00058FD242 | AAA family ATPase | NA |
| UHGV-0118282_60 | eggNOG-mapper | 1345695.CLSA_c30180 | AAA domain | NA |
| UHGV-0118282_60 | Pfam | PF13479 | AAA domain | AAA_24 |
| UHGV-0118282_60 | Structural annotation | PF13479, MF_00350, TIGR01618, COG0468 | NA | NA |
| UHGV-0118282_61 | PHROG | phrog_253 | Mu Gam-like end protection | DNA, RNA and nucleotide metabolism |
| UHGV-0118282_61 | UniRef90 | UniRef90_UPI00051BDF29 | siphovirus Gp157 family protein | NA |
| UHGV-0118282_61 | eggNOG-mapper | 1449050.JNLE01000005_gene3949 | Siphovirus Gp157 | NA |
| UHGV-0118282_61 | Pfam | PF05565 | Siphovirus Gp157 | Sipho_Gp157 |
| UHGV-0118282_61 | Structural annotation | PF05565, NF002139 | NA | NA |
| UHGV-0118282_63 | KOfam | K06284 | abrB; AbrB family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes | NA |
| UHGV-0118282_63 | PHROG | phrog_4681 | antitoxin from a toxin-antitoxin system | moron, auxiliary metabolic gene and host takeover |
| UHGV-0118282_63 | UniRef90 | UniRef90_R6Y144 | Transcriptional regulator AbrB family | NA |
| UHGV-0118282_63 | eggNOG-mapper | 574376.BAMA_10335 | SpoVT / AbrB like domain | NA |
| UHGV-0118282_63 | Pfam | PF04014 | Antidote-toxin recognition MazE, bacterial antitoxin | MazE_antitoxin |
| UHGV-0118282_63 | Pfam | PF13240 | zinc-ribbon domain | zinc_ribbon_2 |
| UHGV-0118282_63 | NCBIFam | TIGR01439.1 | transcriptional regulator, AbrB family | NA |
| UHGV-0118282_63 | COG | COG2002 | Bifunctional DNA-binding transcriptional regulator of stationary/sporulation/toxin gene expression and antitoxin component of the YhaV-PrlF toxin-antitoxin module | NA |
| UHGV-0118282_67 | Structural annotation | PF21531, NF033787 | NA | NA |
| UHGV-0118282_68 | KOfam | K07741 | antB; anti-repressor protein | NA |
| UHGV-0118282_68 | PHROG | phrog_63 | anti-repressor Ant | transcription regulation |
| UHGV-0118282_68 | UniRef90 | UniRef90_A0A1H8KVS3 | Anti-repressor protein | NA |
| UHGV-0118282_68 | eggNOG-mapper | 663952.SDD27957_09340 | AntA/AntB antirepressor | NA |
| UHGV-0118282_68 | Pfam | PF08346 | AntA/AntB antirepressor | AntA |
| UHGV-0118282_68 | Pfam | PF03374 | Phage antirepressor protein KilAC domain | ANT |
| UHGV-0118282_68 | COG | COG3561 | Phage anti-repressor protein Ant | NA |
| UHGV-0118282_68 | Structural annotation | PF03374, PF08346, TIGR02681, COG3645, COG3561 | NA | NA |
| UHGV-0118282_69 | UniRef90 | UniRef90_A0A3D1PJT4 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-0118282_69 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0118282_69 | COG | COG1476 | DNA-binding transcriptional regulator, XRE-family HTH domain | NA |
| UHGV-0118282_69 | Structural annotation | PF01381, NF041951, COG1476 | NA | NA |
| UHGV-0118282_70 | KOfam | K01356 | lexA; repressor LexA [EC:3.4.21.88] | NA |
| UHGV-0118282_70 | PHROG | phrog_4 | transcriptional repressor | transcription regulation |
| UHGV-0118282_70 | UniRef90 | UniRef90_R5YSE6 | Peptidase_S24 domain-containing protein | NA |
| UHGV-0118282_70 | eggNOG-mapper | 748727.CLJU_c36670 | Peptidase S24-like | NA |
| UHGV-0118282_70 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0118282_70 | Pfam | PF00717 | Peptidase S24-like | Peptidase_S24 |
| UHGV-0118282_70 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0118282_70 | Structural annotation | PF00717, PF01381, MF_00015, TIGR00498, NF010465, COG1974, COG1476 | NA | NA |
| UHGV-0118282_71 | KOfam | K14059 | int; integrase | NA |
| UHGV-0118282_71 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-0118282_71 | UniRef90 | UniRef90_R6HDS7 | Phage integrase | NA |
| UHGV-0118282_71 | eggNOG-mapper | 857293.CAAU_0761 | Belongs to the 'phage' integrase family | NA |
| UHGV-0118282_71 | Pfam | PF14659 | Phage integrase, N-terminal SAM-like domain | Phage_int_SAM_3 |
| UHGV-0118282_71 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-0118282_71 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-0118282_71 | Structural annotation | PF00589, MF_02055, TIGR02224, COG4974 | NA | NA |