| UHGV-0035441_7 | KOfam | K03427 | hsdM; type I restriction enzyme M protein [EC:2.1.1.72] | NA |
| UHGV-0035441_7 | PHROG | phrog_5696 | NA | unknown function |
| UHGV-0035441_7 | UniRef90 | UniRef90_A0A6L5XAE6 | N-6 DNA methylase | NA |
| UHGV-0035441_7 | eggNOG-mapper | 997884.HMPREF1068_00007 | COG0286 Type I restriction-modification system methyltransferase subunit | NA |
| UHGV-0035441_7 | Pfam | PF02384 | N-6 DNA Methylase | N6_Mtase |
| UHGV-0035441_7 | COG | COG0286 | Type I restriction-modification system, DNA methylase subunit | NA |
| UHGV-0035441_7 | Structural annotation | COG0286 | NA | NA |
| UHGV-0035441_15 | Structural annotation | PF12857 | NA | NA |
| UHGV-0035441_18 | Structural annotation | PF06289, COG1582 | NA | NA |
| UHGV-0035441_19 | KOfam | K01972 | E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2] | NA |
| UHGV-0035441_19 | PHROG | phrog_3869 | NAD-dependent DNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-0035441_19 | UniRef90 | UniRef90_UPI001CC7263E | NAD-dependent DNA ligase LigA | NA |
| UHGV-0035441_19 | eggNOG-mapper | 1123248.KB893386_gene1852 | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA | NA |
| UHGV-0035441_19 | Pfam | PF01653 | NAD-dependent DNA ligase adenylation domain | DNA_ligase_aden |
| UHGV-0035441_19 | COG | COG0272 | NAD-dependent DNA ligase | NA |
| UHGV-0035441_19 | Structural annotation | PF01653, PF03120, MF_01588, NF005932, COG0272 | NA | NA |
| UHGV-0035441_21 | KOfam | K03496 | parA, soj; chromosome partitioning protein | NA |
| UHGV-0035441_21 | PHROG | phrog_164 | ParA-like partition protein | DNA, RNA and nucleotide metabolism |
| UHGV-0035441_21 | UniRef90 | UniRef90_A0A353E5C8 | AAA_31 domain-containing protein | NA |
| UHGV-0035441_21 | eggNOG-mapper | 1236504.HMPREF2132_02105 | CobQ CobB MinD ParA nucleotide binding domain | NA |
| UHGV-0035441_21 | Pfam | PF13614 | AAA domain | AAA_31 |
| UHGV-0035441_21 | COG | COG1192 | ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ | NA |
| UHGV-0035441_21 | Structural annotation | PF13614, MF_00533, NF041283, COG1192 | NA | NA |
| UHGV-0035441_23 | Structural annotation | PF12502, MF_02248 | NA | NA |
| UHGV-0035441_24 | UniRef90 | UniRef90_D1PE27 | RepB family plasmid replication initiator protein | NA |
| UHGV-0035441_24 | eggNOG-mapper | 1122983.BAJY01000004_gene1777 | Initiator RepB protein | NA |
| UHGV-0035441_24 | COG | COG5527 | Protein involved in initiation of plasmid replication | NA |
| UHGV-0035441_24 | Structural annotation | PF20964, PF01051, NF038290, COG5527 | NA | NA |
| UHGV-0035441_27 | Structural annotation | PF17457 | NA | NA |
| UHGV-0035441_28 | Structural annotation | COG3655 | NA | NA |
| UHGV-0035441_30 | PHROG | phrog_255 | exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0035441_30 | UniRef90 | UniRef90_A0A353E5D6 | NA | NA |
| UHGV-0035441_30 | eggNOG-mapper | 1236504.HMPREF2132_01690 | DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease | NA |
| UHGV-0035441_30 | Pfam | PF16473 | 3'-5' exoribonuclease Rv2179c-like domain | Rv2179c-like |
| UHGV-0035441_30 | COG | COG0847 | DNA polymerase III, epsilon subunit or related 3'-5' exonuclease | NA |
| UHGV-0035441_30 | Structural annotation | PF16473, MF_00157, TIGR01298, COG5018 | NA | NA |
| UHGV-0035441_32 | UniRef90 | UniRef90_A0A096AGU9 | FHA domain-containing protein | NA |
| UHGV-0035441_32 | eggNOG-mapper | 1236504.HMPREF2132_01700 | DNA primase activity | NA |
| UHGV-0035441_32 | COG | COG0358 | DNA primase (bacterial type) | NA |
| UHGV-0035441_32 | Structural annotation | PF05272, PF01807, MF_00974, MF_00016, NF005477, COG3378, COG0358 | NA | NA |
| UHGV-0035441_35 | KOfam | K02338 | dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] | NA |
| UHGV-0035441_35 | PHROG | phrog_947 | DNA polymerase processivity factor | DNA, RNA and nucleotide metabolism |
| UHGV-0035441_35 | UniRef90 | UniRef90_A0A7X6VW07 | Beta sliding clamp | NA |
| UHGV-0035441_35 | eggNOG-mapper | 755732.Fluta_2407 | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria | NA |
| UHGV-0035441_35 | Pfam | PF00712 | DNA polymerase III beta subunit, N-terminal domain | DNA_pol3_beta |
| UHGV-0035441_35 | Pfam | PF02768 | DNA polymerase III beta subunit, C-terminal domain | DNA_pol3_beta_3 |
| UHGV-0035441_35 | COG | COG0592 | DNA polymerase III sliding clamp (beta) subunit, PCNA homolog | NA |
| UHGV-0035441_35 | Structural annotation | PF02768, PF00712, PF02767, MF_00317, TIGR00663, COG0592 | NA | NA |
| UHGV-0035441_37 | Structural annotation | PF08863 | NA | NA |
| UHGV-0035441_42 | eggNOG-mapper | 1002367.HMPREF0673_02207 | NA | NA |
| UHGV-0035441_42 | Structural annotation | PF04466, PF20441, MF_04145, TIGR01547, COG1783 | NA | NA |
| UHGV-0035441_44 | PHROG | phrog_799 | DNA methyltransferase | other |
| UHGV-0035441_44 | UniRef90 | UniRef90_A0A096B9T1 | Conjugal transfer protein | NA |
| UHGV-0035441_44 | eggNOG-mapper | 1236504.HMPREF2132_01885 | DNA restriction-modification system | NA |
| UHGV-0035441_44 | COG | COG0827 | Adenine-specific DNA N6-methylase | NA |
| UHGV-0035441_44 | Structural annotation | PF03848, MF_02100, NF000058, COG2263 | NA | NA |
| UHGV-0035441_46 | KOfam | K00390 | cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] | NA |
| UHGV-0035441_46 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-0035441_46 | UniRef90 | UniRef90_UPI001C38E333 | phosphoadenosine phosphosulfate reductase family protein | NA |
| UHGV-0035441_46 | eggNOG-mapper | 357276.EL88_11445 | Phosphoadenosine phosphosulfate reductase family | NA |
| UHGV-0035441_46 | PADLOC | BrxP_00001 | BrxP | BREX |
| UHGV-0035441_46 | Pfam | PF01507 | Phosphoadenosine phosphosulfate reductase family | PAPS_reduct |
| UHGV-0035441_46 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-0035441_46 | Structural annotation | PF01507, MF_00064, NF006327, COG0175 | NA | NA |
| UHGV-0035441_49 | UniRef90 | UniRef90_UPI001C2BD57F | phage holin family protein | NA |
| UHGV-0035441_49 | eggNOG-mapper | 457424.BFAG_02443 | NA | NA |
| UHGV-0035441_49 | Pfam | PF05105 | Bacteriophage holin family | Phage_holin_4_1 |
| UHGV-0035441_49 | Structural annotation | TIGR01593 | NA | NA |
| UHGV-0035441_50 | Structural annotation | PF20765 | NA | NA |
| UHGV-0035441_52 | PHROG | phrog_28 | tail length tape measure protein | tail |
| UHGV-0035441_52 | UniRef90 | UniRef90_A0A2L2WS53 | PhageMin_Tail domain-containing protein | NA |
| UHGV-0035441_52 | eggNOG-mapper | 1236504.HMPREF2132_01670 | tail tape measure protein, TP901 family | NA |
| UHGV-0035441_52 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-0035441_52 | NCBIFam | TIGR01760.1 | phage tail tape measure protein | NA |
| UHGV-0035441_52 | COG | COG5283 | Phage-related tail protein | NA |
| UHGV-0035441_54 | UniRef90 | UniRef90_A0A2L2WND9 | Primase C terminal 2 | NA |
| UHGV-0035441_54 | eggNOG-mapper | 1236504.HMPREF2132_01765 | Primase C terminal 2 (PriCT-2) | NA |
| UHGV-0035441_54 | PADLOC | drt-cluster64 | DRT | DRT |
| UHGV-0035441_54 | Pfam | PF08800 | BT4734-like, N-terminal domain | BT4734-like_N |
| UHGV-0035441_54 | COG | COG5545 | Predicted P-loop ATPase and inactivated derivatives | NA |
| UHGV-0035441_54 | Structural annotation | PF08800, NF040562 | NA | NA |
| UHGV-0035441_55 | KOfam | K00942 | gmk, GUK1; guanylate kinase [EC:2.7.4.8] | NA |
| UHGV-0035441_55 | PHROG | phrog_1815 | guanylate kinase | other |
| UHGV-0035441_55 | UniRef90 | UniRef90_A0A354WXC5 | Guanylate kinase | NA |
| UHGV-0035441_55 | eggNOG-mapper | 742727.HMPREF9447_00732 | Guanylate kinase | NA |
| UHGV-0035441_55 | Pfam | PF00625 | Guanylate kinase | Guanylate_kin |
| UHGV-0035441_55 | COG | COG0194 | Guanylate kinase | NA |
| UHGV-0035441_55 | Structural annotation | PF00625, MF_00328, NF011324, COG0194 | NA | NA |
| UHGV-0035441_56 | KOfam | K03465 | thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148] | NA |
| UHGV-0035441_56 | PHROG | phrog_85 | thymidylate synthase | DNA, RNA and nucleotide metabolism |
| UHGV-0035441_56 | UniRef90 | UniRef90_A0A8F0WBE8 | Flavin-dependent thymidylate synthase | NA |
| UHGV-0035441_56 | eggNOG-mapper | 1236504.HMPREF2132_01775 | thymidylate synthase (FAD) activity | NA |
| UHGV-0035441_56 | Pfam | PF02511 | Thymidylate synthase complementing protein | Thy1 |
| UHGV-0035441_56 | COG | COG1351 | Thymidylate synthase ThyX, FAD-dependent family | NA |
| UHGV-0035441_56 | Structural annotation | PF02511, MF_01408, TIGR02170, COG1351 | NA | NA |
| UHGV-0035441_57 | PHROG | phrog_229 | MazG-like pyrophosphatase | other |
| UHGV-0035441_57 | UniRef90 | UniRef90_A0A353E7W6 | MazG domain-containing protein | NA |
| UHGV-0035441_57 | eggNOG-mapper | 1236504.HMPREF2132_01780 | Mazg nucleotide pyrophosphohydrolase | NA |
| UHGV-0035441_57 | Pfam | PF03819 | MazG nucleotide pyrophosphohydrolase domain | MazG |
| UHGV-0035441_57 | COG | COG1694 | NTP pyrophosphatase, house-cleaning of non-canonical NTPs | NA |
| UHGV-0035441_57 | Structural annotation | TIGR03188, COG1694 | NA | NA |
| UHGV-0035441_60 | Structural annotation | PF11550, COG5437 | NA | NA |
| UHGV-0035441_61 | KOfam | K21511 | GPC; capsid assembly protease [EC:3.4.21.-] | NA |
| UHGV-0035441_61 | PHROG | phrog_53 | head maturation protease | head and packaging |
| UHGV-0035441_61 | UniRef90 | UniRef90_A0A2L2WN07 | Signal peptide peptidase SppA, 36K type | NA |
| UHGV-0035441_61 | eggNOG-mapper | 1236504.HMPREF2132_01855 | serine-type peptidase activity | NA |
| UHGV-0035441_61 | Pfam | PF01343 | Peptidase family S49 | Peptidase_S49 |
| UHGV-0035441_61 | COG | COG0616 | Periplasmic serine protease, ClpP class | NA |
| UHGV-0035441_61 | Structural annotation | PF01343, MF_00444, TIGR00706, COG0616 | NA | NA |
| UHGV-0035441_62 | Structural annotation | PF05065, PF18998, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0035441_63 | Structural annotation | TIGR01603, COG5437 | NA | NA |
| UHGV-0035441_64 | KOfam | K11921 | cynR; LysR family transcriptional regulator, cyn operon transcriptional activator | NA |
| UHGV-0035441_64 | PHROG | phrog_3736 | NA | unknown function |
| UHGV-0035441_64 | UniRef90 | UniRef90_A0A353E8E6 | HTH lysR-type domain-containing protein | NA |
| UHGV-0035441_64 | eggNOG-mapper | 1121890.AUDO01000009_gene38 | Transcriptional regulator | NA |
| UHGV-0035441_64 | Pfam | PF00126 | Bacterial regulatory helix-turn-helix protein, lysR family | HTH_1 |
| UHGV-0035441_64 | Pfam | PF03466 | LysR substrate binding domain | LysR_substrate |
| UHGV-0035441_64 | COG | COG0583 | DNA-binding transcriptional regulator, LysR family | NA |
| UHGV-0035441_64 | Structural annotation | PF03466, PF00126, MF_01233, NF040786, COG0583 | NA | NA |
| UHGV-0035441_67 | Structural annotation | PF10628 | NA | NA |
| UHGV-0035441_72 | PHROG | phrog_874 | NA | unknown function |
| UHGV-0035441_72 | eggNOG-mapper | 762968.HMPREF9441_00541 | NA | NA |
| UHGV-0035441_72 | Structural annotation | PF04266, MF_00684, NF003443, COG4405 | NA | NA |
| UHGV-0035441_75 | PHROG | phrog_8684 | NA | unknown function |
| UHGV-0035441_75 | UniRef90 | UniRef90_UPI001F45D98B | YopX family protein | NA |
| UHGV-0035441_75 | eggNOG-mapper | 742767.HMPREF9456_02048 | YopX protein | NA |
| UHGV-0035441_75 | Pfam | PF09643 | YopX protein | YopX |
| UHGV-0035441_75 | Structural annotation | PF09643, TIGR01671 | NA | NA |
| UHGV-0035441_79 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-0035441_79 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-0035441_79 | UniRef90 | UniRef90_A0A353E5E4 | Cytosine-specific methyltransferase | NA |
| UHGV-0035441_79 | eggNOG-mapper | 1033733.CAEK01000007_gene1648 | Cytosine-specific methyltransferase | NA |
| UHGV-0035441_79 | PADLOC | MTase_II_00058 | Type II methyltransferase | RM |
| UHGV-0035441_79 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-0035441_79 | NCBIFam | TIGR00675.1 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-0035441_79 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-0035441_79 | Structural annotation | PF00145, MF_02237, TIGR00675, COG0270 | NA | NA |
| UHGV-0035441_84 | KOfam | K03395 | aac3-I; aminoglycoside 3-N-acetyltransferase I [EC:2.3.1.60] | NA |
| UHGV-0035441_84 | UniRef90 | UniRef90_A0A6I1S5I8 | GNAT family N-acetyltransferase | NA |
| UHGV-0035441_84 | Pfam | PF00583 | Acetyltransferase (GNAT) family | Acetyltransf_1 |
| UHGV-0035441_84 | COG | COG0454 | N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) | NA |
| UHGV-0035441_84 | Structural annotation | PF13673, MF_02018, NF000487, COG3153 | NA | NA |
| UHGV-0035441_85 | PHROG | phrog_1383 | virion structural protein | head and packaging |
| UHGV-0035441_85 | UniRef90 | UniRef90_R6U473 | Gp142 | NA |
| UHGV-0035441_85 | eggNOG-mapper | 1327935.A0A060AD14_9CAUD | NA | NA |
| UHGV-0035441_85 | Structural annotation | COG1704 | NA | NA |
| UHGV-0035441_86 | PHROG | phrog_2087 | NA | unknown function |
| UHGV-0035441_86 | eggNOG-mapper | 985665.HPL003_12540 | NA | NA |
| UHGV-0035441_87 | Structural annotation | PF13619 | NA | NA |
| UHGV-0035441_88 | eggNOG-mapper | 1235803.C825_03414 | NA | NA |
| UHGV-0035441_88 | Structural annotation | PF05136, MF_04135, TIGR01540, COG5518 | NA | NA |
| UHGV-0035441_89 | KOfam | K00571 | E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] | NA |
| UHGV-0035441_89 | PHROG | phrog_67 | DNA methyltransferase | other |
| UHGV-0035441_89 | UniRef90 | UniRef90_A0A255TPS1 | Methyltransferase | NA |
| UHGV-0035441_89 | eggNOG-mapper | 908612.HMPREF9720_1695 | DNA methylase | NA |
| UHGV-0035441_89 | PADLOC | MTase_II_00157 | Type II methyltransferase | RM |
| UHGV-0035441_89 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-0035441_89 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-0035441_89 | Structural annotation | PF01555, MF_01872, NF008572, COG0863 | NA | NA |
| UHGV-0035441_90 | Pfam | PF20459 | NA | DUF6712 |
| UHGV-0035441_90 | Structural annotation | PF20459 | NA | NA |
| UHGV-0035441_95 | PHROG | phrog_17422 | NA | unknown function |
| UHGV-0035441_95 | eggNOG-mapper | 1203550.HMPREF1475_00568 | cellulase activity | NA |
| UHGV-0035441_95 | COG | COG4926 | Phage-related protein | NA |
| UHGV-0035441_96 | PHROG | phrog_3267 | tail protein | tail |
| UHGV-0035441_96 | UniRef90 | UniRef90_E1KUD5 | Ig-like domain-containing protein | NA |
| UHGV-0035441_96 | eggNOG-mapper | 1392486.JIAF01000004_gene2044 | NA | NA |
| UHGV-0035441_96 | Structural annotation | PF02010, MF_04116, NF010681, COG1361 | NA | NA |
| UHGV-0035441_97 | UniRef90 | UniRef90_UPI001C2B9C90 | carbohydrate binding domain-containing protein | NA |
| UHGV-0035441_97 | eggNOG-mapper | 571.MC52_21290 | Phage-related protein, tail component | NA |
| UHGV-0035441_97 | Pfam | PF02018 | Carbohydrate binding domain | CBM_4_9 |
| UHGV-0035441_97 | COG | COG0845 | Multidrug efflux pump subunit AcrA (membrane-fusion protein) | NA |
| UHGV-0035441_97 | Structural annotation | PF15425, PF17997, PF18957, NF033675, NF040788 | NA | NA |
| UHGV-0035441_98 | UniRef90 | UniRef90_UPI001F431ADA | BspA family leucine-rich repeat surface protein | NA |
| UHGV-0035441_98 | Pfam | PF03382 | NA | DUF285 |
| UHGV-0035441_98 | NCBIFam | TIGR02167.1 | bacterial surface protein 26-residue repeat | NA |
| UHGV-0035441_98 | Structural annotation | PF03382, PF16640, PF18315, NF032891 | NA | NA |
| UHGV-0035441_99 | UniRef90 | UniRef90_UPI001F1F31EC | NA | NA |
| UHGV-0035441_99 | eggNOG-mapper | 411479.BACUNI_00733 | NA | NA |
| UHGV-0035441_99 | Pfam | PF14301 | NA | DUF4376 |
| UHGV-0035441_99 | Structural annotation | PF14301 | NA | NA |
| UHGV-0035441_100 | eggNOG-mapper | 411479.BACUNI_00732 | NA | NA |
| UHGV-0035441_101 | PHROG | phrog_1501 | NA | unknown function |
| UHGV-0035441_101 | UniRef90 | UniRef90_R6EVM2 | NA | NA |
| UHGV-0035441_101 | eggNOG-mapper | 679935.Alfi_0537 | NA | NA |
| UHGV-0035441_101 | Pfam | PF18925 | NA | DUF5675 |
| UHGV-0035441_101 | Structural annotation | PF18925 | NA | NA |
| UHGV-0035441_103 | Structural annotation | PF18692, TIGR03066, NF007705 | NA | NA |
| UHGV-0035441_104 | UniRef90 | UniRef90_R6YPV7 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-0035441_104 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-0035441_106 | UniRef90 | UniRef90_A0A1I5MYP3 | Fructokinase | NA |
| UHGV-0035441_106 | eggNOG-mapper | 471854.Dfer_5528 | NA | NA |