| UHGV-0003468_2 | PHROG | phrog_87 | metallo-protease | other |
| UHGV-0003468_2 | UniRef90 | UniRef90_A0A3R6K8Y6 | Peptidase_M78 domain-containing protein | NA |
| UHGV-0003468_2 | eggNOG-mapper | 553973.CLOHYLEM_07298 | IrrE N-terminal-like domain | NA |
| UHGV-0003468_2 | Pfam | PF06114 | IrrE N-terminal-like domain | Peptidase_M78 |
| UHGV-0003468_2 | COG | COG2856 | Zn-dependent peptidase ImmA, M78 family | NA |
| UHGV-0003468_2 | Structural annotation | PF06114, COG2856 | NA | NA |
| UHGV-0003468_3 | KOfam | K22299 | rghR; HTH-type transcriptional regulator, competence development regulator | NA |
| UHGV-0003468_3 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-0003468_3 | UniRef90 | UniRef90_A0A3B9CD23 | XRE family transcriptional regulator | NA |
| UHGV-0003468_3 | eggNOG-mapper | 1256908.HMPREF0373_00219 | sequence-specific DNA binding | NA |
| UHGV-0003468_3 | PADLOC | retron_type_VI_hth_cluster2_1 | NA | Retron |
| UHGV-0003468_3 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0003468_3 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0003468_3 | Structural annotation | PF12844, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-0003468_4 | UniRef90 | UniRef90_A0A3B9CCY2 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-0003468_4 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-0003468_4 | Structural annotation | PF01381, NF041951, COG1476 | NA | NA |
| UHGV-0003468_7 | Structural annotation | PF13601, MF_01819, NF008565, COG1846 | NA | NA |
| UHGV-0003468_9 | PHROG | phrog_4621 | NA | unknown function |
| UHGV-0003468_9 | eggNOG-mapper | 1415774.U728_1126 | NA | NA |
| UHGV-0003468_10 | PHROG | phrog_6058 | NA | unknown function |
| UHGV-0003468_10 | UniRef90 | UniRef90_A0A4Q7P3C7 | Prolyl-tRNA synthetase | NA |
| UHGV-0003468_10 | eggNOG-mapper | 742733.HMPREF9469_05094 | NA | NA |
| UHGV-0003468_11 | UniRef90 | UniRef90_UPI0015D1C8FF | lectin-1 | NA |
| UHGV-0003468_11 | Structural annotation | COG3296 | NA | NA |
| UHGV-0003468_15 | PHROG | phrog_674 | NA | unknown function |
| UHGV-0003468_15 | UniRef90 | UniRef90_UPI001C01FE50 | NA | NA |
| UHGV-0003468_15 | eggNOG-mapper | 411460.RUMTOR_02065 | NA | NA |
| UHGV-0003468_15 | Pfam | PF07083 | NA | DUF1351 |
| UHGV-0003468_15 | Structural annotation | PF07083 | NA | NA |
| UHGV-0003468_16 | PHROG | phrog_4400 | NA | unknown function |
| UHGV-0003468_16 | eggNOG-mapper | 886882.PPSC2_p0514 | NA | NA |
| UHGV-0003468_16 | dbAPIS | APIS008 | Alphafold2 predicted that Gad2 is an enzyme with a nucleotidyltransferase protein domain, suggesting that it inhibits Gabija via a mechanism of action different than Gad1. | NA |
| UHGV-0003468_16 | Structural annotation | PF01743, MF_00957, TIGR01942, COG0617 | NA | NA |
| UHGV-0003468_17 | PHROG | phrog_155 | Erf-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0003468_17 | UniRef90 | UniRef90_UPI001C031D02 | ERF family protein | NA |
| UHGV-0003468_17 | eggNOG-mapper | 357809.Cphy_2988 | ERF superfamily | NA |
| UHGV-0003468_17 | Pfam | PF04404 | ERF superfamily | ERF |
| UHGV-0003468_17 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-0003468_17 | Structural annotation | PF04404, TIGR00607, COG4712 | NA | NA |
| UHGV-0003468_18 | PHROG | phrog_72 | NinB/ Orf homologous recombination mediator | DNA, RNA and nucleotide metabolism |
| UHGV-0003468_18 | UniRef90 | UniRef90_A0A285PU94 | Recombinase NinB | NA |
| UHGV-0003468_18 | eggNOG-mapper | 1410650.JHWL01000003_gene2850 | NA | NA |
| UHGV-0003468_18 | Structural annotation | PF05772, NF007281 | NA | NA |
| UHGV-0003468_19 | PHROG | phrog_7566 | NA | unknown function |
| UHGV-0003468_19 | UniRef90 | UniRef90_UPI001C0181E7 | phosphoenolpyruvate carboxykinase | NA |
| UHGV-0003468_19 | eggNOG-mapper | 1304866.K413DRAFT_1198 | NA | NA |
| UHGV-0003468_20 | PHROG | phrog_373 | anti-repressor | transcription regulation |
| UHGV-0003468_20 | UniRef90 | UniRef90_UPI001C016064 | ORF6C domain-containing protein | NA |
| UHGV-0003468_20 | eggNOG-mapper | 1304866.K413DRAFT_3008 | Phage regulatory protein | NA |
| UHGV-0003468_20 | Pfam | PF10543 | ORF6N domain | ORF6N |
| UHGV-0003468_20 | Pfam | PF10552 | ORF6C domain | ORF6C |
| UHGV-0003468_20 | COG | COG3646 | Phage regulatory protein Rha | NA |
| UHGV-0003468_20 | Structural annotation | PF10543, TIGR02681, COG3646 | NA | NA |
| UHGV-0003468_21 | KOfam | K01160 | rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10] | NA |
| UHGV-0003468_21 | PHROG | phrog_1682 | RusA-like Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-0003468_21 | UniRef90 | UniRef90_A0A1Q6UYH5 | Endodeoxyribonuclease RusA | NA |
| UHGV-0003468_21 | eggNOG-mapper | 910314.HMPREF9220_1104 | Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC | NA |
| UHGV-0003468_21 | Pfam | PF05866 | Endodeoxyribonuclease RusA | RusA |
| UHGV-0003468_21 | COG | COG4570 | Holliday junction resolvase RusA (prophage-encoded endonuclease) | NA |
| UHGV-0003468_21 | Structural annotation | PF19595, NF007305, COG4570 | NA | NA |
| UHGV-0003468_22 | PHROG | phrog_2514 | DnaD-like helicase loader | DNA, RNA and nucleotide metabolism |
| UHGV-0003468_22 | UniRef90 | UniRef90_A0A1M5ZHR8 | TF_AP-2 domain-containing protein | NA |
| UHGV-0003468_22 | eggNOG-mapper | 742733.HMPREF9469_01845 | NA | NA |
| UHGV-0003468_22 | Structural annotation | PF07106, PF07261, MF_01177, TIGR01714, TIGR01446, COG5529 | NA | NA |
| UHGV-0003468_23 | KOfam | K02315 | dnaC; DNA replication protein DnaC | NA |
| UHGV-0003468_23 | PHROG | phrog_50 | DnaC-like helicase loader | DNA, RNA and nucleotide metabolism |
| UHGV-0003468_23 | UniRef90 | UniRef90_UPI000E81B795 | ATP-binding protein | NA |
| UHGV-0003468_23 | eggNOG-mapper | 742733.HMPREF9469_01844 | IstB-like ATP binding protein | NA |
| UHGV-0003468_23 | Pfam | PF01695 | IstB-like ATP binding protein | IstB_IS21 |
| UHGV-0003468_23 | COG | COG1484 | DNA replication protein DnaC | NA |
| UHGV-0003468_23 | Structural annotation | PF01695, MF_00377, NF005992, COG1484 | NA | NA |
| UHGV-0003468_29 | UniRef90 | UniRef90_A0A1M7SMP6 | NA | NA |
| UHGV-0003468_29 | eggNOG-mapper | 397290.C810_01514 | NA | NA |
| UHGV-0003468_30 | PHROG | phrog_20593 | NA | unknown function |
| UHGV-0003468_31 | PHROG | phrog_874 | NA | unknown function |
| UHGV-0003468_31 | UniRef90 | UniRef90_A0A6N7W7Q7 | ASCH domain-containing protein | NA |
| UHGV-0003468_31 | eggNOG-mapper | 411468.CLOSCI_00298 | NA | NA |
| UHGV-0003468_31 | Structural annotation | PF04266, MF_00684, NF003443, COG4405 | NA | NA |
| UHGV-0003468_34 | KOfam | K00390 | cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] | NA |
| UHGV-0003468_34 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-0003468_34 | UniRef90 | UniRef90_A0A1Q6KUL6 | PAPS_reduct domain-containing protein | NA |
| UHGV-0003468_34 | eggNOG-mapper | 1232452.BAIB02000007_gene1640 | Phosphoadenosine phosphosulfate reductase | NA |
| UHGV-0003468_34 | PADLOC | BrxP_00001 | BrxP | BREX |
| UHGV-0003468_34 | Pfam | PF01507 | Phosphoadenosine phosphosulfate reductase family | PAPS_reduct |
| UHGV-0003468_34 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-0003468_34 | Structural annotation | PF01507, MF_00063, NF010369, COG0175 | NA | NA |
| UHGV-0003468_36 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-0003468_36 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-0003468_36 | UniRef90 | UniRef90_UPI001C035897 | DNA cytosine methyltransferase | NA |
| UHGV-0003468_36 | eggNOG-mapper | 1235800.C819_02255 | C-5 cytosine-specific DNA methylase | NA |
| UHGV-0003468_36 | PADLOC | MTase_II_00020 | Type II methyltransferase | RM |
| UHGV-0003468_36 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-0003468_36 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-0003468_39 | UniRef90 | UniRef90_UPI001C02D4D3 | ABC transporter ATP-binding protein | NA |
| UHGV-0003468_40 | eggNOG-mapper | 1235793.C809_02217 | NA | NA |
| UHGV-0003468_41 | KOfam | K07474 | xtmA; phage terminase small subunit | NA |
| UHGV-0003468_41 | PHROG | phrog_2606 | terminase small subunit | head and packaging |
| UHGV-0003468_41 | UniRef90 | UniRef90_UPI00164AF8F0 | terminase small subunit | NA |
| UHGV-0003468_41 | eggNOG-mapper | 632245.CLP_1640 | terminase, small subunit | NA |
| UHGV-0003468_41 | Pfam | PF06056 | Putative ATPase subunit of terminase (gpP-like) | Terminase_5 |
| UHGV-0003468_41 | Pfam | PF03592 | Terminase small subunit | Terminase_2 |
| UHGV-0003468_41 | COG | COG3728 | Phage terminase, small subunit | NA |
| UHGV-0003468_41 | Structural annotation | PF03592, PF10668, NF040601, COG3728 | NA | NA |
| UHGV-0003468_42 | KOfam | K06909 | xtmB; phage terminase large subunit | NA |
| UHGV-0003468_42 | PHROG | phrog_2 | terminase large subunit | head and packaging |
| UHGV-0003468_42 | UniRef90 | UniRef90_A0A6L5YJQ3 | PBSX family phage terminase large subunit | NA |
| UHGV-0003468_42 | eggNOG-mapper | 903814.ELI_3215 | Phage terminase large subunit | NA |
| UHGV-0003468_42 | Pfam | PF03237 | Terminase large subunit, T4likevirus-type, N-terminal | Terminase_6N |
| UHGV-0003468_42 | NCBIFam | TIGR01547.1 | PBSX family phage terminase large subunit | NA |
| UHGV-0003468_42 | COG | COG1783 | Phage terminase large subunit | NA |
| UHGV-0003468_42 | Structural annotation | PF04466, PF20454, MF_04148, TIGR01547, COG1783 | NA | NA |
| UHGV-0003468_43 | PHROG | phrog_533 | portal protein | head and packaging |
| UHGV-0003468_43 | UniRef90 | UniRef90_A0A1C6CDM8 | Phage portal protein, putative, A118 family | NA |
| UHGV-0003468_43 | eggNOG-mapper | 33035.JPJF01000106_gene3135 | phage minor capsid protein | NA |
| UHGV-0003468_43 | Structural annotation | PF05133, MF_04120, TIGR01542, COG5511 | NA | NA |
| UHGV-0003468_44 | PHROG | phrog_556 | minor head protein | head and packaging |
| UHGV-0003468_44 | UniRef90 | UniRef90_UPI001C0ECC47 | minor capsid protein | NA |
| UHGV-0003468_44 | eggNOG-mapper | 1449050.JNLE01000003_gene3886 | NA | NA |
| UHGV-0003468_44 | Pfam | PF11114 | Minor capsid protein | Minor_capsid_2 |
| UHGV-0003468_44 | Structural annotation | PF11114 | NA | NA |
| UHGV-0003468_45 | PHROG | phrog_581 | minor head protein | head and packaging |
| UHGV-0003468_45 | UniRef90 | UniRef90_UPI000E4E3D5A | phage capsid protein | NA |
| UHGV-0003468_45 | eggNOG-mapper | 411490.ANACAC_00781 | NA | NA |
| UHGV-0003468_45 | Pfam | PF06152 | Phage minor capsid protein 2 | Phage_min_cap2 |
| UHGV-0003468_45 | COG | COG2369 | NA | NA |
| UHGV-0003468_45 | Structural annotation | PF06152 | NA | NA |
| UHGV-0003468_47 | PHROG | phrog_194 | head scaffolding protein | head and packaging |
| UHGV-0003468_47 | UniRef90 | UniRef90_UPI000E538A87 | phage scaffolding protein | NA |
| UHGV-0003468_47 | eggNOG-mapper | 476272.RUMHYD_01775 | COG NOG36366 non supervised orthologous group | NA |
| UHGV-0003468_47 | Pfam | PF06810 | Phage minor structural protein GP20 | Phage_GP20 |
| UHGV-0003468_48 | PHROG | phrog_283 | major head protein | head and packaging |
| UHGV-0003468_48 | UniRef90 | UniRef90_A0A173REC9 | p22 coat protein-gene protein 5 | NA |
| UHGV-0003468_48 | eggNOG-mapper | 411461.DORFOR_01167 | P22 coat protein - gene protein 5 | NA |
| UHGV-0003468_48 | Pfam | PF11651 | P22 coat protein - gene protein 5 | P22_CoatProtein |
| UHGV-0003468_48 | Structural annotation | PF11651, MF_04119, TIGR04387, COG4653 | NA | NA |
| UHGV-0003468_49 | PHROG | phrog_541 | head-tail adaptor | connector |
| UHGV-0003468_49 | eggNOG-mapper | 397290.C810_05226 | NA | NA |
| UHGV-0003468_50 | PHROG | phrog_355 | nucleoside 2-deoxyribosyltransferase | DNA, RNA and nucleotide metabolism |
| UHGV-0003468_50 | UniRef90 | UniRef90_UPI000E473058 | NA | NA |
| UHGV-0003468_50 | eggNOG-mapper | 397290.C810_05229 | NA | NA |
| UHGV-0003468_50 | Structural annotation | PF14359 | NA | NA |
| UHGV-0003468_51 | PHROG | phrog_3366 | NA | unknown function |
| UHGV-0003468_51 | eggNOG-mapper | 476272.RUMHYD_01779 | NA | NA |
| UHGV-0003468_51 | Structural annotation | PF20536, COG5614 | NA | NA |
| UHGV-0003468_52 | PHROG | phrog_3266 | tail completion | connector |
| UHGV-0003468_52 | eggNOG-mapper | 397290.C810_05232 | NA | NA |
| UHGV-0003468_52 | Structural annotation | PF12691 | NA | NA |
| UHGV-0003468_53 | PHROG | phrog_3099 | NA | unknown function |
| UHGV-0003468_53 | eggNOG-mapper | 1235790.C805_00082 | NA | NA |
| UHGV-0003468_53 | Structural annotation | PF06199, TIGR02126, COG5437 | NA | NA |
| UHGV-0003468_54 | PHROG | phrog_11299 | NA | unknown function |
| UHGV-0003468_54 | UniRef90 | UniRef90_A0A412KF72 | RNA polymerase subunit sigma | NA |
| UHGV-0003468_54 | eggNOG-mapper | 1235790.C805_00083 | NA | NA |
| UHGV-0003468_54 | Pfam | PF20378 | NA | DUF6673 |
| UHGV-0003468_54 | Structural annotation | PF10666 | NA | NA |
| UHGV-0003468_55 | PHROG | phrog_706 | NA | unknown function |
| UHGV-0003468_55 | UniRef90 | UniRef90_C7GBZ7 | Bacteriophage Gp15 protein | NA |
| UHGV-0003468_55 | eggNOG-mapper | 1235790.C805_00084 | Bacteriophage Gp15 protein | NA |
| UHGV-0003468_55 | Pfam | PF06854 | Bacteriophage Gp15 protein | Phage_Gp15 |
| UHGV-0003468_55 | Structural annotation | PF06854 | NA | NA |
| UHGV-0003468_56 | KOfam | K10421 | CLIP1, RSN; CAP-Gly domain-containing linker protein 1 | NA |
| UHGV-0003468_56 | PHROG | phrog_1535 | tail length tape measure protein | tail |
| UHGV-0003468_56 | UniRef90 | UniRef90_A0A1C6JZ05 | Phage-related protein | NA |
| UHGV-0003468_56 | eggNOG-mapper | 476272.RUMHYD_01785 | phage tail tape measure protein | NA |
| UHGV-0003468_56 | COG | COG1511 | NA | NA |
| UHGV-0003468_57 | PHROG | phrog_1194 | NA | unknown function |
| UHGV-0003468_57 | eggNOG-mapper | 1235790.C805_00088 | NA | NA |
| UHGV-0003468_57 | Pfam | PF20458 | NA | DUF6711 |
| UHGV-0003468_57 | Structural annotation | PF20458, TIGR01633, COG3499 | NA | NA |
| UHGV-0003468_58 | PHROG | phrog_18190 | NA | unknown function |
| UHGV-0003468_58 | UniRef90 | UniRef90_UPI001C01E293 | tail fiber domain-containing protein | NA |
| UHGV-0003468_58 | eggNOG-mapper | 1235790.C805_00089 | NA | NA |
| UHGV-0003468_58 | Pfam | PF13884 | Chaperone of endosialidase | Peptidase_S74 |
| UHGV-0003468_58 | Structural annotation | PF14594, NF033848, COG3500 | NA | NA |
| UHGV-0003468_59 | PHROG | phrog_17196 | kinase | other |
| UHGV-0003468_59 | UniRef90 | UniRef90_A0A3R6GQJ1 | Peptidase S74 domain-containing protein | NA |
| UHGV-0003468_59 | eggNOG-mapper | 1235790.C805_00090 | NA | NA |
| UHGV-0003468_59 | Pfam | PF13884 | Chaperone of endosialidase | Peptidase_S74 |
| UHGV-0003468_60 | PHROG | phrog_199 | holin | lysis |
| UHGV-0003468_60 | UniRef90 | UniRef90_UPI001C014087 | phage holin family protein | NA |
| UHGV-0003468_60 | eggNOG-mapper | 1232453.BAIF02000059_gene1615 | Bacteriophage holin family | NA |
| UHGV-0003468_60 | Pfam | PF05105 | Bacteriophage holin family | Phage_holin_4_1 |
| UHGV-0003468_60 | NCBIFam | TIGR01593.1 | toxin secretion/phage lysis holin | NA |
| UHGV-0003468_60 | COG | COG4824 | Phage-related holin (Lysis protein) | NA |
| UHGV-0003468_60 | Structural annotation | PF05105, TIGR01593, COG4824 | NA | NA |
| UHGV-0003468_61 | KOfam | K01185 | E3.2.1.17; lysozyme [EC:3.2.1.17] | NA |
| UHGV-0003468_61 | PHROG | phrog_7 | endolysin | lysis |
| UHGV-0003468_61 | UniRef90 | UniRef90_A0A6L6L979 | Lysozyme | NA |
| UHGV-0003468_61 | eggNOG-mapper | 1007096.BAGW01000017_gene780 | Phage lysozyme | NA |
| UHGV-0003468_61 | Pfam | PF00959 | Phage lysozyme | Phage_lysozyme |
| UHGV-0003468_61 | Pfam | PF01471 | Putative peptidoglycan binding domain | PG_binding_1 |
| UHGV-0003468_61 | COG | COG3772 | Phage-related lysozyme (muramidase), GH24 family | NA |
| UHGV-0003468_61 | HAMAP | MF_04110 | Endolysin | NA |
| UHGV-0003468_61 | Structural annotation | PF01471, PF00959, MF_04110, COG3772, COG3409 | NA | NA |