| UHGV-0020041_1 | Structural annotation | TIGR01603, COG5437 | NA | NA |
| UHGV-0020041_2 | Structural annotation | PF05065, PF18998, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0020041_3 | KOfam | K21511 | GPC; capsid assembly protease [EC:3.4.21.-] | NA |
| UHGV-0020041_3 | PHROG | phrog_53 | head maturation protease | head and packaging |
| UHGV-0020041_3 | UniRef90 | UniRef90_A0A2L2WN07 | Signal peptide peptidase SppA, 36K type | NA |
| UHGV-0020041_3 | eggNOG-mapper | 1236504.HMPREF2132_01855 | serine-type peptidase activity | NA |
| UHGV-0020041_3 | Pfam | PF01343 | Peptidase family S49 | Peptidase_S49 |
| UHGV-0020041_3 | COG | COG0616 | Periplasmic serine protease, ClpP class | NA |
| UHGV-0020041_3 | Structural annotation | PF01343, MF_00444, TIGR00706, COG0616 | NA | NA |
| UHGV-0020041_4 | Structural annotation | PF11550, COG5437 | NA | NA |
| UHGV-0020041_7 | PHROG | phrog_229 | MazG-like pyrophosphatase | other |
| UHGV-0020041_7 | UniRef90 | UniRef90_A0A353E7W6 | MazG domain-containing protein | NA |
| UHGV-0020041_7 | eggNOG-mapper | 1236504.HMPREF2132_01780 | Mazg nucleotide pyrophosphohydrolase | NA |
| UHGV-0020041_7 | Pfam | PF03819 | MazG nucleotide pyrophosphohydrolase domain | MazG |
| UHGV-0020041_7 | COG | COG1694 | NTP pyrophosphatase, house-cleaning of non-canonical NTPs | NA |
| UHGV-0020041_7 | Structural annotation | TIGR03188, COG1694 | NA | NA |
| UHGV-0020041_8 | KOfam | K03465 | thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148] | NA |
| UHGV-0020041_8 | PHROG | phrog_85 | thymidylate synthase | DNA, RNA and nucleotide metabolism |
| UHGV-0020041_8 | UniRef90 | UniRef90_A0A345BP42 | Thymidylate synthase complementing protein | NA |
| UHGV-0020041_8 | eggNOG-mapper | 1236504.HMPREF2132_01775 | thymidylate synthase (FAD) activity | NA |
| UHGV-0020041_8 | Pfam | PF02511 | Thymidylate synthase complementing protein | Thy1 |
| UHGV-0020041_8 | COG | COG1351 | Thymidylate synthase ThyX, FAD-dependent family | NA |
| UHGV-0020041_8 | Structural annotation | PF02511, MF_01408, TIGR02170, COG1351 | NA | NA |
| UHGV-0020041_9 | KOfam | K00942 | gmk, GUK1; guanylate kinase [EC:2.7.4.8] | NA |
| UHGV-0020041_9 | PHROG | phrog_1815 | guanylate kinase | other |
| UHGV-0020041_9 | UniRef90 | UniRef90_A0A354WXC5 | Guanylate kinase | NA |
| UHGV-0020041_9 | eggNOG-mapper | 742727.HMPREF9447_00732 | Guanylate kinase | NA |
| UHGV-0020041_9 | Pfam | PF00625 | Guanylate kinase | Guanylate_kin |
| UHGV-0020041_9 | COG | COG0194 | Guanylate kinase | NA |
| UHGV-0020041_9 | Structural annotation | PF00625, MF_00328, TIGR03263, COG0194 | NA | NA |
| UHGV-0020041_10 | UniRef90 | UniRef90_A0A2L2WND9 | Primase C terminal 2 | NA |
| UHGV-0020041_10 | eggNOG-mapper | 1236504.HMPREF2132_01765 | Primase C terminal 2 (PriCT-2) | NA |
| UHGV-0020041_10 | PADLOC | drt-cluster64 | DRT | DRT |
| UHGV-0020041_10 | Pfam | PF08800 | BT4734-like, N-terminal domain | BT4734-like_N |
| UHGV-0020041_10 | COG | COG5545 | Predicted P-loop ATPase and inactivated derivatives | NA |
| UHGV-0020041_10 | Structural annotation | PF08800, NF040562 | NA | NA |
| UHGV-0020041_11 | PHROG | phrog_28 | tail length tape measure protein | tail |
| UHGV-0020041_11 | UniRef90 | UniRef90_A0A2L2WS53 | PhageMin_Tail domain-containing protein | NA |
| UHGV-0020041_11 | eggNOG-mapper | 1236504.HMPREF2132_01670 | tail tape measure protein, TP901 family | NA |
| UHGV-0020041_11 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-0020041_11 | NCBIFam | TIGR01760.1 | phage tail tape measure protein | NA |
| UHGV-0020041_11 | COG | COG5283 | Phage-related tail protein | NA |
| UHGV-0020041_11 | Structural annotation | PF10145, TIGR01760 | NA | NA |
| UHGV-0020041_13 | Structural annotation | PF20765 | NA | NA |
| UHGV-0020041_14 | UniRef90 | UniRef90_UPI001C2BD57F | phage holin family protein | NA |
| UHGV-0020041_14 | eggNOG-mapper | 457424.BFAG_02443 | NA | NA |
| UHGV-0020041_14 | Pfam | PF05105 | Bacteriophage holin family | Phage_holin_4_1 |
| UHGV-0020041_14 | Structural annotation | TIGR01593 | NA | NA |
| UHGV-0020041_17 | KOfam | K00390 | cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] | NA |
| UHGV-0020041_17 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-0020041_17 | UniRef90 | UniRef90_A0A2L2WN54 | Phosphoadenosine phosphosulfate reductase | NA |
| UHGV-0020041_17 | eggNOG-mapper | 762982.HMPREF9442_01221 | Phosphoadenosine phosphosulfate reductase family | NA |
| UHGV-0020041_17 | Pfam | PF01507 | Phosphoadenosine phosphosulfate reductase family | PAPS_reduct |
| UHGV-0020041_17 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-0020041_17 | Structural annotation | PF01507, MF_00064, NF010367, COG0175 | NA | NA |
| UHGV-0020041_19 | PHROG | phrog_799 | DNA methyltransferase | other |
| UHGV-0020041_19 | UniRef90 | UniRef90_A0A096B9T1 | Conjugal transfer protein | NA |
| UHGV-0020041_19 | eggNOG-mapper | 1236504.HMPREF2132_01885 | DNA restriction-modification system | NA |
| UHGV-0020041_19 | COG | COG0827 | Adenine-specific DNA N6-methylase | NA |
| UHGV-0020041_19 | Structural annotation | PF19587, MF_01872, NF011489, COG0286 | NA | NA |
| UHGV-0020041_21 | eggNOG-mapper | 1002367.HMPREF0673_02207 | NA | NA |
| UHGV-0020041_21 | Structural annotation | PF04466, PF20441, MF_04145, TIGR01547, COG1783 | NA | NA |
| UHGV-0020041_26 | Structural annotation | PF08863 | NA | NA |
| UHGV-0020041_28 | KOfam | K02338 | dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] | NA |
| UHGV-0020041_28 | PHROG | phrog_947 | DNA polymerase processivity factor | DNA, RNA and nucleotide metabolism |
| UHGV-0020041_28 | UniRef90 | UniRef90_A0A7X6VW07 | Beta sliding clamp | NA |
| UHGV-0020041_28 | eggNOG-mapper | 755732.Fluta_2407 | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria | NA |
| UHGV-0020041_28 | Pfam | PF00712 | DNA polymerase III beta subunit, N-terminal domain | DNA_pol3_beta |
| UHGV-0020041_28 | Pfam | PF02768 | DNA polymerase III beta subunit, C-terminal domain | DNA_pol3_beta_3 |
| UHGV-0020041_28 | COG | COG0592 | DNA polymerase III sliding clamp (beta) subunit, PCNA homolog | NA |
| UHGV-0020041_28 | Structural annotation | PF02768, PF00712, PF02767, MF_00317, TIGR00663, COG0592 | NA | NA |
| UHGV-0020041_31 | PHROG | phrog_35807 | NA | unknown function |
| UHGV-0020041_31 | eggNOG-mapper | 357276.EL88_12625 | RNA polymerase activity | NA |
| UHGV-0020041_31 | COG | COG0085 | DNA-directed RNA polymerase, beta subunit/140 kD subunit | NA |
| UHGV-0020041_31 | Structural annotation | PF14902 | NA | NA |
| UHGV-0020041_32 | UniRef90 | UniRef90_A0A096AGU9 | FHA domain-containing protein | NA |
| UHGV-0020041_32 | eggNOG-mapper | 1236504.HMPREF2132_01700 | DNA primase activity | NA |
| UHGV-0020041_32 | COG | COG0358 | DNA primase (bacterial type) | NA |
| UHGV-0020041_32 | Structural annotation | PF05272, PF01807, MF_00974, MF_00016, NF005477, COG3378, COG0358 | NA | NA |
| UHGV-0020041_34 | PHROG | phrog_255 | exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0020041_34 | UniRef90 | UniRef90_A0A353E5D6 | NA | NA |
| UHGV-0020041_34 | eggNOG-mapper | 1236504.HMPREF2132_01690 | DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease | NA |
| UHGV-0020041_34 | Pfam | PF16473 | 3'-5' exoribonuclease Rv2179c-like domain | Rv2179c-like |
| UHGV-0020041_34 | COG | COG0847 | DNA polymerase III, epsilon subunit or related 3'-5' exonuclease | NA |
| UHGV-0020041_34 | Structural annotation | PF16473, MF_00157, TIGR01298, COG5018 | NA | NA |
| UHGV-0020041_36 | Structural annotation | COG3655 | NA | NA |
| UHGV-0020041_37 | Structural annotation | PF17457 | NA | NA |
| UHGV-0020041_40 | UniRef90 | UniRef90_A0A6G1TZW9 | Replication initiation protein | NA |
| UHGV-0020041_40 | eggNOG-mapper | 1284775.HMPREF1640_05070 | Initiator RepB protein | NA |
| UHGV-0020041_40 | Pfam | PF21205 | Initiator Rep protein, WH2 | Rep3_C |
| UHGV-0020041_40 | COG | COG5527 | Protein involved in initiation of plasmid replication | NA |
| UHGV-0020041_40 | Structural annotation | PF20964, PF07112, NF010305, COG5527 | NA | NA |
| UHGV-0020041_41 | Structural annotation | PF12502, MF_02248 | NA | NA |
| UHGV-0020041_43 | KOfam | K03496 | parA, soj; chromosome partitioning protein | NA |
| UHGV-0020041_43 | PHROG | phrog_164 | ParA-like partition protein | DNA, RNA and nucleotide metabolism |
| UHGV-0020041_43 | UniRef90 | UniRef90_A0A353E5C8 | AAA_31 domain-containing protein | NA |
| UHGV-0020041_43 | eggNOG-mapper | 1236504.HMPREF2132_02105 | CobQ CobB MinD ParA nucleotide binding domain | NA |
| UHGV-0020041_43 | Pfam | PF13614 | AAA domain | AAA_31 |
| UHGV-0020041_43 | COG | COG1192 | ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ | NA |
| UHGV-0020041_43 | Structural annotation | PF13614, MF_00533, NF041283, COG1192 | NA | NA |
| UHGV-0020041_45 | KOfam | K01972 | E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2] | NA |
| UHGV-0020041_45 | PHROG | phrog_3869 | NAD-dependent DNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-0020041_45 | UniRef90 | UniRef90_A0A7C4P4A2 | DNA ligase | NA |
| UHGV-0020041_45 | eggNOG-mapper | 1123248.KB893386_gene1852 | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA | NA |
| UHGV-0020041_45 | Pfam | PF01653 | NAD-dependent DNA ligase adenylation domain | DNA_ligase_aden |
| UHGV-0020041_45 | COG | COG0272 | NAD-dependent DNA ligase | NA |
| UHGV-0020041_45 | Structural annotation | PF01653, PF03120, MF_01588, NF005932, COG0272 | NA | NA |
| UHGV-0020041_46 | Structural annotation | PF06289, COG1582 | NA | NA |
| UHGV-0020041_49 | Structural annotation | PF12857 | NA | NA |
| UHGV-0020041_57 | eggNOG-mapper | 1433126.BN938_1801 | NA | NA |
| UHGV-0020041_57 | Pfam | PF18847 | Large polyvalent protein associated domain 29 | LPD29 |
| UHGV-0020041_60 | UniRef90 | UniRef90_A0A7J0A8P0 | HTH-type transcriptional regulator SinR | NA |
| UHGV-0020041_60 | eggNOG-mapper | 1268240.ATFI01000020_gene152 | NA | NA |
| UHGV-0020041_60 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0020041_60 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0020041_60 | Structural annotation | PF01381, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-0020041_61 | eggNOG-mapper | 585543.HMPREF0969_03349 | Cro/C1-type HTH DNA-binding domain | NA |
| UHGV-0020041_61 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-0020041_61 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0020041_64 | PHROG | phrog_1501 | NA | unknown function |
| UHGV-0020041_64 | UniRef90 | UniRef90_R6EVM2 | NA | NA |
| UHGV-0020041_64 | eggNOG-mapper | 679935.Alfi_0537 | NA | NA |
| UHGV-0020041_64 | Pfam | PF18925 | NA | DUF5675 |
| UHGV-0020041_64 | Structural annotation | PF18925 | NA | NA |
| UHGV-0020041_65 | UniRef90 | UniRef90_F3PDX9 | Conserved domain protein | NA |
| UHGV-0020041_65 | eggNOG-mapper | 411479.BACUNI_00732 | NA | NA |
| UHGV-0020041_66 | UniRef90 | UniRef90_UPI001F36DCAA | NA | NA |
| UHGV-0020041_66 | eggNOG-mapper | 1122985.HMPREF1991_01560 | NA | NA |
| UHGV-0020041_66 | Pfam | PF14301 | NA | DUF4376 |
| UHGV-0020041_66 | Structural annotation | PF14301 | NA | NA |
| UHGV-0020041_67 | Structural annotation | PF12866, PF13620, PF20942, NF040788, COG2351 | NA | NA |
| UHGV-0020041_68 | PHROG | phrog_38044 | NA | unknown function |
| UHGV-0020041_68 | eggNOG-mapper | 762982.HMPREF9442_01191 | cellulase activity | NA |
| UHGV-0020041_68 | Pfam | PF02018 | Carbohydrate binding domain | CBM_4_9 |
| UHGV-0020041_68 | COG | COG4733 | Phage-related protein, tail protein J | NA |
| UHGV-0020041_68 | Structural annotation | PF00629, PF20073, NF033675 | NA | NA |
| UHGV-0020041_73 | Pfam | PF20459 | NA | DUF6712 |
| UHGV-0020041_73 | Structural annotation | PF20459 | NA | NA |
| UHGV-0020041_74 | KOfam | K00571 | E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] | NA |
| UHGV-0020041_74 | PHROG | phrog_67 | DNA methyltransferase | other |
| UHGV-0020041_74 | UniRef90 | UniRef90_A0A255TPS1 | Methyltransferase | NA |
| UHGV-0020041_74 | eggNOG-mapper | 483215.BACFIN_05771 | Belongs to the N(4) N(6)-methyltransferase family | NA |
| UHGV-0020041_74 | PADLOC | MTase_II_00157 | Type II methyltransferase | RM |
| UHGV-0020041_74 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-0020041_74 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-0020041_74 | Structural annotation | PF01555, MF_01872, NF008572, COG0863 | NA | NA |
| UHGV-0020041_75 | eggNOG-mapper | 1235803.C825_03414 | NA | NA |
| UHGV-0020041_75 | Structural annotation | PF05136, MF_04135, TIGR01540, COG5518 | NA | NA |
| UHGV-0020041_76 | PHROG | phrog_2087 | NA | unknown function |
| UHGV-0020041_76 | eggNOG-mapper | 985665.HPL003_12540 | NA | NA |
| UHGV-0020041_77 | PHROG | phrog_1383 | virion structural protein | head and packaging |
| UHGV-0020041_77 | UniRef90 | UniRef90_R6U473 | Gp142 | NA |
| UHGV-0020041_77 | eggNOG-mapper | 1327935.A0A060AD14_9CAUD | NA | NA |
| UHGV-0020041_77 | Structural annotation | COG1704 | NA | NA |
| UHGV-0020041_78 | KOfam | K03395 | aac3-I; aminoglycoside 3-N-acetyltransferase I [EC:2.3.1.60] | NA |
| UHGV-0020041_78 | UniRef90 | UniRef90_A0A6I1S5I8 | GNAT family N-acetyltransferase | NA |
| UHGV-0020041_78 | Pfam | PF00583 | Acetyltransferase (GNAT) family | Acetyltransf_1 |
| UHGV-0020041_78 | COG | COG0454 | N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) | NA |
| UHGV-0020041_78 | Structural annotation | PF13673, MF_02018, NF000487, COG3153 | NA | NA |
| UHGV-0020041_79 | Structural annotation | COG5475 | NA | NA |
| UHGV-0020041_86 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-0020041_86 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-0020041_86 | UniRef90 | UniRef90_A0A353E5E4 | Cytosine-specific methyltransferase | NA |
| UHGV-0020041_86 | eggNOG-mapper | 1033733.CAEK01000007_gene1648 | Cytosine-specific methyltransferase | NA |
| UHGV-0020041_86 | PADLOC | MTase_II_00058 | Type II methyltransferase | RM |
| UHGV-0020041_86 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-0020041_86 | NCBIFam | TIGR00675.1 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-0020041_86 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-0020041_86 | Structural annotation | PF00145, MF_02237, TIGR00675, COG0270 | NA | NA |
| UHGV-0020041_91 | PHROG | phrog_8684 | NA | unknown function |
| UHGV-0020041_91 | UniRef90 | UniRef90_UPI001F45D98B | YopX family protein | NA |
| UHGV-0020041_91 | eggNOG-mapper | 445970.ALIPUT_01614 | YopX protein | NA |
| UHGV-0020041_91 | Pfam | PF09643 | YopX protein | YopX |
| UHGV-0020041_91 | Structural annotation | PF09643, TIGR01671 | NA | NA |
| UHGV-0020041_93 | KOfam | K14415 | RTCB, rtcB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8] | NA |
| UHGV-0020041_93 | PHROG | phrog_1075 | tRNA splicing ligase | DNA, RNA and nucleotide metabolism |
| UHGV-0020041_93 | UniRef90 | UniRef90_A0A413CCX6 | RNA-splicing ligase RtcB | NA |
| UHGV-0020041_93 | eggNOG-mapper | 1089548.KI783301_gene2001 | tRNA-splicing ligase RtcB | NA |
| UHGV-0020041_93 | Pfam | PF01139 | tRNA-splicing ligase RtcB | RtcB |
| UHGV-0020041_93 | COG | COG1690 | RNA-splicing ligase RtcB, repairs tRNA damage | NA |
| UHGV-0020041_93 | Structural annotation | PF01139, MF_03144, NF007153, COG1690 | NA | NA |
| UHGV-0020041_94 | PHROG | phrog_1374 | NA | unknown function |
| UHGV-0020041_94 | Pfam | PF10269 | Transmembrane Fragile-X-F protein | Tmemb_185A |
| UHGV-0020041_99 | PHROG | phrog_874 | NA | unknown function |
| UHGV-0020041_99 | eggNOG-mapper | 762968.HMPREF9441_00541 | NA | NA |
| UHGV-0020041_99 | Structural annotation | PF04266, MF_00684, NF003443, COG4405 | NA | NA |
| UHGV-0020041_105 | Structural annotation | PF10628 | NA | NA |
| UHGV-0020041_108 | KOfam | K11921 | cynR; LysR family transcriptional regulator, cyn operon transcriptional activator | NA |
| UHGV-0020041_108 | PHROG | phrog_3736 | NA | unknown function |
| UHGV-0020041_108 | UniRef90 | UniRef90_A0A353E8E6 | HTH lysR-type domain-containing protein | NA |
| UHGV-0020041_108 | eggNOG-mapper | 1121890.AUDO01000009_gene38 | Transcriptional regulator | NA |
| UHGV-0020041_108 | Pfam | PF00126 | Bacterial regulatory helix-turn-helix protein, lysR family | HTH_1 |
| UHGV-0020041_108 | Pfam | PF03466 | LysR substrate binding domain | LysR_substrate |
| UHGV-0020041_108 | COG | COG0583 | DNA-binding transcriptional regulator, LysR family | NA |
| UHGV-0020041_108 | Structural annotation | PF03466, PF00126, MF_01233, NF040786, COG0583 | NA | NA |
| UHGV-0020041_109 | eggNOG-mapper | 1095752.HMPREF9969_2503 | Rhodopirellula transposase DDE domain | NA |
| UHGV-0020041_109 | COG | COG3335 | Transposase | NA |