| UHGV-1341133_1 | PHROG | phrog_10089 | DarB-like antirestriction | moron, auxiliary metabolic gene and host takeover |
| UHGV-1341133_1 | UniRef90 | UniRef90_A0A3D0X8D0 | Helicase ATP-binding domain-containing protein (Fragment) | NA |
| UHGV-1341133_1 | eggNOG-mapper | 397288.C806_03713 | helicase C-terminal domain protein | NA |
| UHGV-1341133_1 | Pfam | PF18760 | ADP-Ribosyltransferase in polyvalent proteins | ART-PolyVal |
| UHGV-1341133_1 | Pfam | PF00176 | SNF2-related domain | SNF2-rel_dom |
| UHGV-1341133_1 | Pfam | PF18857 | Large polyvalent protein associated domain 38 | LPD38 |
| UHGV-1341133_1 | COG | COG0553 | Superfamily II DNA or RNA helicase, SNF2 family | NA |
| UHGV-1341133_3 | KOfam | K21471 | cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] | NA |
| UHGV-1341133_3 | PHROG | phrog_329 | minor tail protein | tail |
| UHGV-1341133_3 | UniRef90 | UniRef90_A0A355JE00 | Peptidase C51 domain-containing protein | NA |
| UHGV-1341133_3 | eggNOG-mapper | 1487921.DP68_07190 | NLP P60 protein | NA |
| UHGV-1341133_3 | Pfam | PF01832 | Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase | Glucosaminidase |
| UHGV-1341133_3 | Pfam | PF00877 | NlpC/P60 family | NLPC_P60 |
| UHGV-1341133_3 | COG | COG0791 | Cell wall-associated hydrolase, NlpC_P60 family | NA |
| UHGV-1341133_4 | KOfam | K01448 | amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | NA |
| UHGV-1341133_4 | PHROG | phrog_435 | endolysin | lysis |
| UHGV-1341133_4 | UniRef90 | UniRef90_A0A1C5N460 | Sporulation-specific N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-1341133_4 | eggNOG-mapper | 272563.CD630_09720 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-1341133_4 | Pfam | PF01520 | N-acetylmuramoyl-L-alanine amidase | Amidase_3 |
| UHGV-1341133_4 | COG | COG0860 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-1341133_4 | Structural annotation | PF01520, PF18342, MF_00417, TIGR02883, COG0860, COG4991 | NA | NA |
| UHGV-1341133_5 | PHROG | phrog_918 | NA | unknown function |
| UHGV-1341133_5 | UniRef90 | UniRef90_UPI001CCDC3EB | NA | NA |
| UHGV-1341133_5 | eggNOG-mapper | 1140001.I571_01827 | NA | NA |
| UHGV-1341133_5 | Pfam | PF19791 | NA | DUF6275 |
| UHGV-1341133_5 | Structural annotation | PF19791 | NA | NA |
| UHGV-1341133_6 | eggNOG-mapper | 397290.C810_05225 | NA | NA |
| UHGV-1341133_7 | PHROG | phrog_37799 | NA | unknown function |
| UHGV-1341133_7 | UniRef90 | UniRef90_R6NA79 | Toxin secretion/phage lysis holin | NA |
| UHGV-1341133_7 | eggNOG-mapper | 272563.CD630_06610 | Bacteriophage holin family | NA |
| UHGV-1341133_7 | Pfam | PF05105 | Bacteriophage holin family | Phage_holin_4_1 |
| UHGV-1341133_7 | NCBIFam | TIGR01593.1 | toxin secretion/phage lysis holin | NA |
| UHGV-1341133_7 | COG | COG4824 | Phage-related holin (Lysis protein) | NA |
| UHGV-1341133_7 | Structural annotation | PF05105, TIGR01593, COG4824 | NA | NA |
| UHGV-1341133_8 | KOfam | K24248 | EMID1; EMI domain-containing protein 1 | NA |
| UHGV-1341133_8 | PHROG | phrog_819 | tail protein | tail |
| UHGV-1341133_8 | eggNOG-mapper | 1536769.P40081_01140 | NA | NA |
| UHGV-1341133_8 | Pfam | PF01391 | Collagen triple helix repeat (20 copies) | Collagen |
| UHGV-1341133_10 | UniRef90 | UniRef90_R6MQV2 | Tail Collar domain protein | NA |
| UHGV-1341133_10 | Structural annotation | PF01696, NF000420, COG3420 | NA | NA |
| UHGV-1341133_12 | Structural annotation | PF09144, NF038393 | NA | NA |
| UHGV-1341133_15 | PHROG | phrog_511 | internal virion protein | head and packaging |
| UHGV-1341133_15 | eggNOG-mapper | 1449126.JQKL01000002_gene1688 | NA | NA |
| UHGV-1341133_16 | Structural annotation | PF20387 | NA | NA |
| UHGV-1341133_18 | PHROG | phrog_14242 | major head protein | head and packaging |
| UHGV-1341133_18 | UniRef90 | UniRef90_A0A355JD53 | Phage major capsid protein | NA |
| UHGV-1341133_18 | eggNOG-mapper | 588581.Cpap_1528 | NA | NA |
| UHGV-1341133_18 | NCBIFam | NF033394.1 | phage major capsid protein | NA |
| UHGV-1341133_18 | Structural annotation | PF17236, MF_04133, NF033394, COG4653 | NA | NA |
| UHGV-1341133_20 | PHROG | phrog_156 | portal protein | head and packaging |
| UHGV-1341133_20 | eggNOG-mapper | 588581.Cpap_1526 | NA | NA |
| UHGV-1341133_20 | Structural annotation | PF16510, MF_04120, TIGR01538, COG4383 | NA | NA |
| UHGV-1341133_21 | UniRef90 | UniRef90_A0A7X6VKT0 | C2H2-type domain-containing protein | NA |
| UHGV-1341133_21 | Structural annotation | PF21169 | NA | NA |
| UHGV-1341133_22 | KOfam | K06909 | xtmB; phage terminase large subunit | NA |
| UHGV-1341133_22 | PHROG | phrog_979 | terminase large subunit | head and packaging |
| UHGV-1341133_22 | UniRef90 | UniRef90_A0A355JD48 | Terminase_3 domain-containing protein | NA |
| UHGV-1341133_22 | eggNOG-mapper | 1232449.BAHV02000016_gene1824 | NA | NA |
| UHGV-1341133_22 | Pfam | PF04466 | Phage terminase large subunit | Terminase_3 |
| UHGV-1341133_22 | COG | COG1783 | Phage terminase large subunit | NA |
| UHGV-1341133_22 | Structural annotation | PF04466, PF20454, MF_04148, TIGR01547, COG1783 | NA | NA |
| UHGV-1341133_23 | Structural annotation | PF06056, COG2963 | NA | NA |
| UHGV-1341133_27 | eggNOG-mapper | 1095750.HMPREF9970_2261 | NA | NA |
| UHGV-1341133_27 | Structural annotation | PF03869, NF041793, COG4691 | NA | NA |
| UHGV-1341133_29 | Structural annotation | PF02796, COG2771 | NA | NA |
| UHGV-1341133_31 | KOfam | K03040 | rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] | NA |
| UHGV-1341133_31 | UniRef90 | UniRef90_A0A416CVN3 | RNA_pol_A_CTD domain-containing protein | NA |
| UHGV-1341133_31 | eggNOG-mapper | 1410638.JHXJ01000004_gene2091 | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates | NA |
| UHGV-1341133_31 | Pfam | PF03118 | Bacterial RNA polymerase, alpha chain C terminal domain | RNA_pol_A_CTD |
| UHGV-1341133_31 | COG | COG0202 | DNA-directed RNA polymerase, alpha subunit/40 kD subunit | NA |
| UHGV-1341133_32 | PHROG | phrog_6802 | NA | unknown function |
| UHGV-1341133_32 | eggNOG-mapper | 1256908.HMPREF0373_03028 | NA | NA |
| UHGV-1341133_33 | PHROG | phrog_419 | NA | unknown function |
| UHGV-1341133_33 | UniRef90 | UniRef90_UPI001CC11C4F | PGDYG domain-containing protein | NA |
| UHGV-1341133_33 | eggNOG-mapper | 1134413.ANNK01000120_gene2032 | NA | NA |
| UHGV-1341133_34 | KOfam | K19779 | ralR; endodeoxyribonuclease RalR [EC:3.1.-.-] | NA |
| UHGV-1341133_34 | PHROG | phrog_2245 | nucleoside triphosphate pyrophosphohydrolase | other |
| UHGV-1341133_34 | UniRef90 | UniRef90_A0A1C5STJ7 | MazG domain-containing protein | NA |
| UHGV-1341133_34 | eggNOG-mapper | 56780.SYN_03368 | translation initiation factor activity | NA |
| UHGV-1341133_34 | Pfam | PF14354 | Restriction alleviation protein Lar | Lar_restr_allev |
| UHGV-1341133_34 | NCBIFam | TIGR03655.1 | Lar family restriction alleviation protein | NA |
| UHGV-1341133_34 | dbAPIS | APIS033 | Lar is functionally similar to RaI, is able to alleviate restriction and enhance modification by EcoKI. And the nucleotide sequences of their genes share 47% identity, indicating a common origin. | NA |
| UHGV-1341133_34 | COG | COG1601 | Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain | NA |
| UHGV-1341133_34 | Structural annotation | PF14354, COG3478 | NA | NA |
| UHGV-1341133_38 | KOfam | K07699 | spo0A; two-component system, response regulator, stage 0 sporulation protein A | NA |
| UHGV-1341133_38 | PHROG | phrog_37855 | NA | unknown function |
| UHGV-1341133_38 | UniRef90 | UniRef90_A0A645DV58 | Stage 0 sporulation protein A | NA |
| UHGV-1341133_38 | eggNOG-mapper | 642492.Clole_1756 | May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process | NA |
| UHGV-1341133_38 | Pfam | PF08769 | Sporulation initiation factor Spo0A C terminal | Spo0A_C |
| UHGV-1341133_38 | COG | COG2197 | DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains | NA |
| UHGV-1341133_38 | Structural annotation | PF08769, TIGR02875 | NA | NA |
| UHGV-1341133_39 | PHROG | phrog_4400 | NA | unknown function |
| UHGV-1341133_39 | eggNOG-mapper | 357809.Cphy_2990 | NA | NA |
| UHGV-1341133_39 | dbAPIS | APIS008 | Alphafold2 predicted that Gad2 is an enzyme with a nucleotidyltransferase protein domain, suggesting that it inhibits Gabija via a mechanism of action different than Gad1. | NA |
| UHGV-1341133_39 | Structural annotation | PF01743, MF_00957, NF008634, COG0617 | NA | NA |
| UHGV-1341133_40 | PHROG | phrog_1770 | Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-1341133_40 | eggNOG-mapper | 536233.CLO_1822 | NA | NA |
| UHGV-1341133_40 | Structural annotation | PF02075, MF_00034, NF000711, COG0817 | NA | NA |
| UHGV-1341133_41 | KOfam | K02086 | dnaD; DNA replication protein | NA |
| UHGV-1341133_41 | PHROG | phrog_2562 | replication initiation protein | DNA, RNA and nucleotide metabolism |
| UHGV-1341133_41 | UniRef90 | UniRef90_UPI00137AD09D | NA | NA |
| UHGV-1341133_41 | eggNOG-mapper | 445971.ANASTE_00700 | NA | NA |
| UHGV-1341133_41 | Pfam | PF14297 | Lin1244/Lin1753-like, N-terminal | Lin1244_N |
| UHGV-1341133_41 | Pfam | PF07261 | Replication initiation and membrane attachment | DnaB_2 |
| UHGV-1341133_41 | NCBIFam | TIGR01446.1 | DnaD domain protein | NA |
| UHGV-1341133_41 | COG | COG3935 | DNA replication protein DnaD | NA |
| UHGV-1341133_41 | Structural annotation | PF14297, PF07261, TIGR01446, COG3935 | NA | NA |
| UHGV-1341133_42 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-1341133_42 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-1341133_42 | UniRef90 | UniRef90_R6M3F2 | Single-stranded DNA-binding protein | NA |
| UHGV-1341133_42 | eggNOG-mapper | 1291050.JAGE01000001_gene1719 | Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism | NA |
| UHGV-1341133_42 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-1341133_42 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-1341133_42 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-1341133_42 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-1341133_42 | Structural annotation | PF00436, MF_00984, NF005241, COG0629 | NA | NA |
| UHGV-1341133_44 | PHROG | phrog_398 | NA | unknown function |
| UHGV-1341133_44 | UniRef90 | UniRef90_UPI00137A6F13 | putative HNHc nuclease | NA |
| UHGV-1341133_44 | eggNOG-mapper | 1485543.JMME01000021_gene802 | Putative HNHc nuclease | NA |
| UHGV-1341133_44 | Pfam | PF16784 | Putative HNHc nuclease | HNHc_6 |
| UHGV-1341133_44 | Structural annotation | PF16784 | NA | NA |
| UHGV-1341133_45 | KOfam | K06167 | phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55] | NA |
| UHGV-1341133_45 | PHROG | phrog_392 | metal-dependent hydrolase | other |
| UHGV-1341133_45 | UniRef90 | UniRef90_A0A7X8XIL0 | MBL fold metallo-hydrolase | NA |
| UHGV-1341133_45 | eggNOG-mapper | 665956.HMPREF1032_03101 | May be involved in the transport of PQQ or its precursor to the periplasm | NA |
| UHGV-1341133_45 | Pfam | PF12706 | Beta-lactamase superfamily domain | Lactamase_B_2 |
| UHGV-1341133_45 | COG | COG1235 | Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase | NA |
| UHGV-1341133_45 | Structural annotation | PF12706, MF_01818, TIGR03307, COG1234 | NA | NA |
| UHGV-1341133_46 | KOfam | K07455 | recT; recombination protein RecT | NA |
| UHGV-1341133_46 | PHROG | phrog_148 | RecT-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-1341133_46 | UniRef90 | UniRef90_UPI001D034282 | recombinase RecT | NA |
| UHGV-1341133_46 | eggNOG-mapper | 1095750.HMPREF9970_1675 | RecT family | NA |
| UHGV-1341133_46 | Pfam | PF03837 | RecT family | RecT |
| UHGV-1341133_46 | NCBIFam | TIGR00616.1 | recombinase, phage RecT family | NA |
| UHGV-1341133_46 | COG | COG3723 | Recombinational DNA repair protein RecT | NA |
| UHGV-1341133_46 | Structural annotation | PF03837, TIGR00616, COG3723 | NA | NA |
| UHGV-1341133_47 | PHROG | phrog_674 | NA | unknown function |
| UHGV-1341133_47 | UniRef90 | UniRef90_A0A416D4U8 | NA | NA |
| UHGV-1341133_47 | eggNOG-mapper | 1408437.JNJN01000039_gene373 | NA | NA |
| UHGV-1341133_47 | Pfam | PF07083 | NA | DUF1351 |
| UHGV-1341133_47 | Structural annotation | PF07083 | NA | NA |
| UHGV-1341133_48 | Structural annotation | PF09943 | NA | NA |
| UHGV-1341133_50 | PHROG | phrog_1029 | NA | unknown function |
| UHGV-1341133_50 | UniRef90 | UniRef90_M1QIB9 | Phage-related protein | NA |
| UHGV-1341133_50 | eggNOG-mapper | 1078085.HMPREF1210_01165 | NA | NA |
| UHGV-1341133_50 | Structural annotation | PF10065, COG5532 | NA | NA |
| UHGV-1341133_51 | PHROG | phrog_997 | replication terminator | DNA, RNA and nucleotide metabolism |
| UHGV-1341133_51 | UniRef90 | UniRef90_R6MCS9 | NA | NA |
| UHGV-1341133_51 | eggNOG-mapper | 1519439.JPJG01000059_gene1910 | NA | NA |
| UHGV-1341133_52 | Structural annotation | PF17574 | NA | NA |
| UHGV-1341133_53 | Structural annotation | PF10922 | NA | NA |
| UHGV-1341133_57 | PHROG | phrog_3150 | NA | unknown function |
| UHGV-1341133_57 | eggNOG-mapper | 580331.Thit_1411 | NA | NA |
| UHGV-1341133_59 | KOfam | K22300 | dicA; HTH-type transcriptional regulator, cell division transcriptional repressor | NA |
| UHGV-1341133_59 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-1341133_59 | UniRef90 | UniRef90_A0A542AKC5 | DNA-binding XRE family transcriptional regulator | NA |
| UHGV-1341133_59 | eggNOG-mapper | 218284.CCDN010000001_gene1646 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-1341133_59 | PADLOC | retron_type_VI_hth_cluster2_1 | NA | Retron |
| UHGV-1341133_59 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1341133_59 | COG | COG1476 | DNA-binding transcriptional regulator, XRE-family HTH domain | NA |
| UHGV-1341133_59 | Structural annotation | PF01381, MF_00535, NF041951, COG1396 | NA | NA |
| UHGV-1341133_60 | KOfam | K22300 | dicA; HTH-type transcriptional regulator, cell division transcriptional repressor | NA |
| UHGV-1341133_60 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-1341133_60 | UniRef90 | UniRef90_R6MT43 | DNA-binding helix-turn-helix protein | NA |
| UHGV-1341133_60 | eggNOG-mapper | 411460.RUMTOR_02056 | Bacteriophage CI repressor helix-turn-helix domain | NA |
| UHGV-1341133_60 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1341133_60 | COG | COG3093 | Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain | NA |
| UHGV-1341133_60 | Structural annotation | PF12844, MF_00584, NF041951, COG1476 | NA | NA |
| UHGV-1341133_61 | PHROG | phrog_87 | metallo-protease | other |
| UHGV-1341133_61 | UniRef90 | UniRef90_R6NN10 | Peptidase_M78 domain-containing protein | NA |
| UHGV-1341133_61 | eggNOG-mapper | 536232.CLM_2576 | IrrE N-terminal-like domain | NA |
| UHGV-1341133_61 | Pfam | PF06114 | IrrE N-terminal-like domain | Peptidase_M78 |
| UHGV-1341133_61 | COG | COG2856 | Zn-dependent peptidase ImmA, M78 family | NA |
| UHGV-1341133_61 | Structural annotation | PF06114, COG2856 | NA | NA |
| UHGV-1341133_63 | eggNOG-mapper | 1120998.AUFC01000015_gene1569 | competence protein COMEC | NA |
| UHGV-1341133_63 | COG | COG2333 | DNA uptake channel protein ComEC C-terminal domain, metallo-beta-lactamase superfamily | NA |
| UHGV-1341133_64 | KOfam | K14059 | int; integrase | NA |
| UHGV-1341133_64 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-1341133_64 | UniRef90 | UniRef90_R6MY37 | Putative integrase | NA |
| UHGV-1341133_64 | eggNOG-mapper | 1507.HMPREF0262_00307 | Phage integrase family | NA |
| UHGV-1341133_64 | Pfam | PF14659 | Phage integrase, N-terminal SAM-like domain | Phage_int_SAM_3 |
| UHGV-1341133_64 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-1341133_64 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-1341133_64 | Structural annotation | PF00589, PF14659, MF_02055, TIGR02224, COG4974 | NA | NA |