| UHGV-0259903_1 | PHROG | phrog_124 | Sak4-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0259903_1 | UniRef90 | UniRef90_A0A1L6BY46 | Nucleotide-binding protein | NA |
| UHGV-0259903_2 | PHROG | phrog_3724 | NA | unknown function |
| UHGV-0259903_2 | Pfam | PF05037 | NA | DUF669 |
| UHGV-0259903_3 | UniRef90 | UniRef90_A0A5H2TVW2 | VRR-NUC domain-containing protein | NA |
| UHGV-0259903_3 | eggNOG-mapper | 350688.Clos_1296 | pfam vrr-nuc | NA |
| UHGV-0259903_3 | COG | COG1591 | Holliday junction resolvase Hjc, archaeal type | NA |
| UHGV-0259903_4 | PHROG | phrog_1485 | NA | unknown function |
| UHGV-0259903_4 | UniRef90 | UniRef90_R6M0A1 | NA | NA |
| UHGV-0259903_4 | eggNOG-mapper | 938278.CAJO01000051_gene805 | NA | NA |
| UHGV-0259903_4 | Pfam | PF07659 | Nucleotide modification associated domain 1 | DUF1599 |
| UHGV-0259903_5 | KOfam | K14440 | SMARCAL1, HARP; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:5.6.2.-] | NA |
| UHGV-0259903_5 | PHROG | phrog_62 | DNA helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0259903_5 | UniRef90 | UniRef90_A0A1L6BY27 | Helicase | NA |
| UHGV-0259903_5 | eggNOG-mapper | 935948.KE386495_gene1203 | SNF2 family N-terminal domain | NA |
| UHGV-0259903_5 | PADLOC | ZorD1_00005 | SWI2/SNF2 helicase, Mrr-like nuclease | Zorya |
| UHGV-0259903_5 | Pfam | PF00176 | SNF2-related domain | SNF2-rel_dom |
| UHGV-0259903_5 | Pfam | PF00271 | Helicase conserved C-terminal domain | Helicase_C |
| UHGV-0259903_5 | COG | COG0553 | Superfamily II DNA or RNA helicase, SNF2 family | NA |
| UHGV-0259903_5 | Structural annotation | PF00176, PF00271, MF_01821, NF041790, COG0553 | NA | NA |
| UHGV-0259903_8 | PHROG | phrog_33386 | NA | unknown function |
| UHGV-0259903_8 | Pfam | PF07498 | Rho termination factor, N-terminal domain | Rho_N |
| UHGV-0259903_10 | PHROG | phrog_13256 | NA | unknown function |
| UHGV-0259903_10 | eggNOG-mapper | 1226322.HMPREF1545_00166 | NA | NA |
| UHGV-0259903_11 | PHROG | phrog_21357 | endolysin | lysis |
| UHGV-0259903_11 | UniRef90 | UniRef90_G9YP37 | SLH domain-containing protein | NA |
| UHGV-0259903_11 | eggNOG-mapper | 97139.C824_00684 | lysozyme activity | NA |
| UHGV-0259903_11 | Pfam | PF05257 | CHAP domain | CHAP |
| UHGV-0259903_11 | COG | COG1388 | LysM repeat | NA |
| UHGV-0259903_11 | Structural annotation | PF10030, TIGR02594, COG4322 | NA | NA |
| UHGV-0259903_12 | eggNOG-mapper | 552398.HMPREF0866_01159 | NA | NA |
| UHGV-0259903_14 | PHROG | phrog_1220 | head protein | head and packaging |
| UHGV-0259903_14 | eggNOG-mapper | 1033737.CAEV01000028_gene283 | NA | NA |
| UHGV-0259903_15 | PHROG | phrog_538 | minor tail protein | tail |
| UHGV-0259903_15 | UniRef90 | UniRef90_UPI0006B2A1E0 | siphovirus ReqiPepy6 Gp37-like family protein | NA |
| UHGV-0259903_15 | eggNOG-mapper | 536232.CLM_2044 | Siphovirus ReqiPepy6 Gp37-like protein | NA |
| UHGV-0259903_15 | Pfam | PF14594 | Siphovirus ReqiPepy6 Gp37-like protein | Sipho_Gp37 |
| UHGV-0259903_15 | Structural annotation | PF14594, TIGR01665, COG4926 | NA | NA |
| UHGV-0259903_16 | PHROG | phrog_36410 | NA | unknown function |
| UHGV-0259903_16 | UniRef90 | UniRef90_A0A7X9C3E1 | Phage tail family protein | NA |
| UHGV-0259903_16 | eggNOG-mapper | 431943.CKL_4056 | Phage tail protein | NA |
| UHGV-0259903_16 | COG | COG4722 | Phage-related protein YomH | NA |
| UHGV-0259903_16 | Structural annotation | PF20753, PF16774, TIGR01633, COG4722 | NA | NA |
| UHGV-0259903_17 | PHROG | phrog_1533 | tail length tape measure protein | tail |
| UHGV-0259903_17 | UniRef90 | UniRef90_A0A1B2DVD5 | PhageMin_Tail domain-containing protein | NA |
| UHGV-0259903_17 | eggNOG-mapper | 35241.Q9AYV8_BPTU2 | peptidoglycan catabolic process | NA |
| UHGV-0259903_17 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-0259903_17 | NCBIFam | TIGR01760.1 | phage tail tape measure protein | NA |
| UHGV-0259903_18 | PHROG | phrog_6280 | NA | unknown function |
| UHGV-0259903_18 | UniRef90 | UniRef90_A0A8J6PH67 | Esterase | NA |
| UHGV-0259903_18 | eggNOG-mapper | 445335.CBN_3078 | NA | NA |
| UHGV-0259903_19 | PHROG | phrog_6686 | tail tube protein | tail |
| UHGV-0259903_19 | UniRef90 | UniRef90_A0A1C6KI12 | S-l_SbsC_C domain-containing protein | NA |
| UHGV-0259903_19 | eggNOG-mapper | 871584.D9ZNE2_9CAUD | NA | NA |
| UHGV-0259903_19 | Structural annotation | PF06488, TIGR01603, COG3498 | NA | NA |
| UHGV-0259903_20 | PHROG | phrog_7585 | NA | unknown function |
| UHGV-0259903_20 | eggNOG-mapper | 1443122.Z958_05865 | NA | NA |
| UHGV-0259903_20 | Structural annotation | PF05657, COG5003 | NA | NA |
| UHGV-0259903_21 | eggNOG-mapper | 1304880.JAGB01000002_gene2213 | NA | NA |
| UHGV-0259903_21 | Structural annotation | PF04883, TIGR01725 | NA | NA |
| UHGV-0259903_22 | PHROG | phrog_8435 | NA | unknown function |
| UHGV-0259903_22 | Structural annotation | PF07405, TIGR01563, COG5614 | NA | NA |
| UHGV-0259903_23 | PHROG | phrog_4020 | NA | unknown function |
| UHGV-0259903_23 | eggNOG-mapper | 748727.CLJU_c31290 | NA | NA |
| UHGV-0259903_24 | Structural annotation | PF07498 | NA | NA |
| UHGV-0259903_25 | PHROG | phrog_29 | major head protein | head and packaging |
| UHGV-0259903_25 | UniRef90 | UniRef90_UPI00082C04A5 | major capsid protein | NA |
| UHGV-0259903_25 | eggNOG-mapper | 756499.Desde_1083 | Phage major capsid protein E | NA |
| UHGV-0259903_25 | Pfam | PF03864 | Phage major capsid protein E | Phage_cap_E |
| UHGV-0259903_25 | Structural annotation | PF03864, MF_04133, NF041162, COG4653 | NA | NA |
| UHGV-0259903_26 | PHROG | phrog_909 | major head protein | head and packaging |
| UHGV-0259903_26 | UniRef90 | UniRef90_A0A512PLH0 | Putative structural protein-phage associated | NA |
| UHGV-0259903_26 | eggNOG-mapper | 1158612.I580_01911 | NA | NA |
| UHGV-0259903_26 | Structural annotation | PF02924 | NA | NA |
| UHGV-0259903_27 | PHROG | phrog_2303 | head scaffolding protein | head and packaging |
| UHGV-0259903_27 | eggNOG-mapper | 986075.CathTA2_2461 | NA | NA |
| UHGV-0259903_27 | Structural annotation | PF10788, MF_02110 | NA | NA |
| UHGV-0259903_29 | PHROG | phrog_1657 | head morphogenesis | head and packaging |
| UHGV-0259903_29 | UniRef90 | UniRef90_A0A349YJR5 | ADPrib_exo_Tox domain-containing protein | NA |
| UHGV-0259903_29 | eggNOG-mapper | 1121342.AUCO01000012_gene1699 | NA | NA |
| UHGV-0259903_29 | Pfam | PF04233 | Phage Mu protein F like protein | Phage_Mu_F |
| UHGV-0259903_29 | Pfam | PF03496 | ADP-ribosyltransferase exoenzyme | ADPrib_exo_Tox |
| UHGV-0259903_29 | NCBIFam | TIGR01641.1 | minor capsid protein | NA |
| UHGV-0259903_31 | PHROG | phrog_64 | portal protein | head and packaging |
| UHGV-0259903_31 | UniRef90 | UniRef90_UPI0008331C88 | phage portal protein | NA |
| UHGV-0259903_31 | eggNOG-mapper | 1121342.AUCO01000012_gene1700 | Phage portal protein, SPP1 Gp6-like | NA |
| UHGV-0259903_31 | Pfam | PF05133 | Phage portal protein, SPP1 Gp6-like | Phage_prot_Gp6 |
| UHGV-0259903_31 | Structural annotation | PF05133, MF_04120, TIGR01538, COG3567 | NA | NA |
| UHGV-0259903_33 | KOfam | K06909 | xtmB; phage terminase large subunit | NA |
| UHGV-0259903_33 | PHROG | phrog_3717 | terminase large subunit | head and packaging |
| UHGV-0259903_33 | UniRef90 | UniRef90_UPI00101D64CF | PBSX family phage terminase large subunit | NA |
| UHGV-0259903_33 | eggNOG-mapper | 536232.CLM_2529 | Phage terminase, large subunit, PBSX family | NA |
| UHGV-0259903_33 | Pfam | PF04466 | Phage terminase large subunit | Terminase_3 |
| UHGV-0259903_33 | Pfam | PF17288 | Terminase RNAseH like domain | Terminase_3C |
| UHGV-0259903_33 | NCBIFam | TIGR01547.1 | PBSX family phage terminase large subunit | NA |
| UHGV-0259903_33 | COG | COG1783 | Phage terminase large subunit | NA |
| UHGV-0259903_33 | Structural annotation | PF04466, PF17288, MF_04145, TIGR01547, COG1783 | NA | NA |
| UHGV-0259903_34 | KOfam | K07474 | xtmA; phage terminase small subunit | NA |
| UHGV-0259903_34 | PHROG | phrog_2606 | terminase small subunit | head and packaging |
| UHGV-0259903_34 | UniRef90 | UniRef90_A0A1Y0YDW3 | Terminase | NA |
| UHGV-0259903_34 | eggNOG-mapper | 279010.BL03830 | phage terminase small subunit | NA |
| UHGV-0259903_34 | Pfam | PF03592 | Terminase small subunit | Terminase_2 |
| UHGV-0259903_34 | COG | COG3728 | Phage terminase, small subunit | NA |
| UHGV-0259903_34 | Structural annotation | PF03592, PF10668, NF040601, COG3728 | NA | NA |
| UHGV-0259903_35 | Structural annotation | MF_01387 | NA | NA |
| UHGV-0259903_37 | PHROG | phrog_6072 | NA | unknown function |
| UHGV-0259903_38 | PHROG | phrog_33402 | NA | unknown function |
| UHGV-0259903_41 | PHROG | phrog_22389 | NA | unknown function |
| UHGV-0259903_41 | Structural annotation | PF01402, COG4710 | NA | NA |
| UHGV-0259903_42 | KOfam | K01493 | comEB; dCMP deaminase [EC:3.5.4.12] | NA |
| UHGV-0259903_42 | PHROG | phrog_174 | dCMP deaminase | DNA, RNA and nucleotide metabolism |
| UHGV-0259903_42 | UniRef90 | UniRef90_A0A523APF6 | Cytidine deaminase | NA |
| UHGV-0259903_42 | eggNOG-mapper | 224325.AF_1764 | PFAM CMP dCMP deaminase zinc-binding | NA |
| UHGV-0259903_42 | PADLOC | dCTPase | NA | NA |
| UHGV-0259903_42 | Pfam | PF00383 | Cytidine and deoxycytidylate deaminase zinc-binding region | dCMP_cyt_deam_1 |
| UHGV-0259903_42 | COG | COG2131 | Deoxycytidylate deaminase | NA |
| UHGV-0259903_42 | Structural annotation | PF00383, MF_00972, TIGR02571, COG2131 | NA | NA |
| UHGV-0259903_47 | KOfam | K01449 | cwlJ, sleB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | NA |
| UHGV-0259903_47 | PHROG | phrog_30550 | NA | unknown function |
| UHGV-0259903_47 | UniRef90 | UniRef90_UPI0018992D54 | cell wall hydrolase | NA |
| UHGV-0259903_47 | eggNOG-mapper | 1449063.JMLS01000019_gene5660 | Cell Wall Hydrolase | NA |
| UHGV-0259903_47 | COG | COG3409 | Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases | NA |
| UHGV-0259903_47 | Structural annotation | TIGR02869 | NA | NA |
| UHGV-0259903_50 | PHROG | phrog_1221 | NA | unknown function |
| UHGV-0259903_50 | UniRef90 | UniRef90_A0A843GH20 | NA | NA |
| UHGV-0259903_50 | eggNOG-mapper | 1235798.C817_00381 | NA | NA |
| UHGV-0259903_50 | Pfam | PF06067 | NA | DUF932 |
| UHGV-0259903_50 | NCBIFam | TIGR03299.1 | phage/plasmid-like protein TIGR03299 | NA |
| UHGV-0259903_50 | Structural annotation | PF06067, TIGR03299 | NA | NA |
| UHGV-0259903_53 | KOfam | K05521 | draG; ADP-ribosyl-[dinitrogen reductase] hydrolase [EC:3.2.2.24] | NA |
| UHGV-0259903_53 | PHROG | phrog_6572 | ADP-ribosylglycohydrolase | other |
| UHGV-0259903_53 | UniRef90 | UniRef90_UPI001E34568B | ADP-ribosylglycohydrolase family protein | NA |
| UHGV-0259903_53 | eggNOG-mapper | 411465.PEPMIC_00852 | ADP-ribosylglycohydrolase | NA |
| UHGV-0259903_53 | Pfam | PF03747 | ADP-ribosylglycohydrolase | ADP_ribosyl_GH |
| UHGV-0259903_53 | COG | COG1397 | ADP-ribosylglycohydrolase | NA |
| UHGV-0259903_53 | Structural annotation | PF03747, NF041672, COG1397 | NA | NA |
| UHGV-0259903_54 | PHROG | phrog_421 | NA | unknown function |
| UHGV-0259903_54 | UniRef90 | UniRef90_UPI001C8E55BC | NA | NA |
| UHGV-0259903_54 | eggNOG-mapper | 349161.Dred_0988 | NA | NA |
| UHGV-0259903_54 | Pfam | PF10979 | NA | DUF2786 |
| UHGV-0259903_54 | COG | COG1451 | UTP pyrophosphatase, metal-dependent hydrolase family | NA |
| UHGV-0259903_54 | Structural annotation | PF10979 | NA | NA |
| UHGV-0259903_56 | PHROG | phrog_5889 | NA | unknown function |
| UHGV-0259903_56 | UniRef90 | UniRef90_A0A5H2TSQ8 | HD domain-containing protein | NA |
| UHGV-0259903_56 | eggNOG-mapper | 1280692.AUJL01000009_gene2990 | Metal dependent phosphohydrolases with conserved 'HD' motif. | NA |
| UHGV-0259903_56 | Pfam | PF01966 | HD domain | HD |
| UHGV-0259903_57 | KOfam | K03465 | thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148] | NA |
| UHGV-0259903_57 | PHROG | phrog_85 | thymidylate synthase | DNA, RNA and nucleotide metabolism |
| UHGV-0259903_57 | UniRef90 | UniRef90_UPI00047D4F18 | FAD-dependent thymidylate synthase | NA |
| UHGV-0259903_57 | eggNOG-mapper | 1336241.JAEB01000001_gene147 | Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant | NA |
| UHGV-0259903_57 | Pfam | PF02511 | Thymidylate synthase complementing protein | Thy1 |
| UHGV-0259903_57 | NCBIFam | TIGR02170.1 | FAD-dependent thymidylate synthase | NA |
| UHGV-0259903_57 | COG | COG1351 | Thymidylate synthase ThyX, FAD-dependent family | NA |
| UHGV-0259903_57 | Structural annotation | PF02511, MF_01408, TIGR02170, COG1351 | NA | NA |
| UHGV-0259903_58 | PHROG | phrog_2250 | NA | unknown function |
| UHGV-0259903_59 | KOfam | K07505 | repA; regulatory protein RepA | NA |
| UHGV-0259903_59 | PHROG | phrog_3123 | NA | unknown function |
| UHGV-0259903_59 | UniRef90 | UniRef90_A0A316NYT9 | RepB_primase domain-containing protein | NA |
| UHGV-0259903_59 | eggNOG-mapper | 304371.MCP_2164 | COG0467 RecA-superfamily ATPases implicated in signal transduction | NA |
| UHGV-0259903_59 | Pfam | PF16793 | RepB DNA-primase from phage plasmid | RepB_primase |
| UHGV-0259903_59 | Pfam | PF13481 | AAA domain | AAA_25 |
| UHGV-0259903_59 | COG | COG0467 | RecA-superfamily ATPase, KaiC/GvpD/RAD55 family | NA |
| UHGV-0259903_59 | Structural annotation | PF13481, PF16793, MF_00350, TIGR00416, NF040562, COG3598 | NA | NA |
| UHGV-0259903_60 | Structural annotation | PF13521, MF_00165, TIGR00041, COG1428 | NA | NA |
| UHGV-0259903_61 | PHROG | phrog_12184 | nucleotide pyrophosphohydrolase | other |
| UHGV-0259903_61 | UniRef90 | UniRef90_A0A843GTV8 | dUTP diphosphatase | NA |
| UHGV-0259903_61 | Pfam | PF08761 | dUTPase | dUTPase_2 |
| UHGV-0259903_61 | Structural annotation | PF08761 | NA | NA |
| UHGV-0259903_62 | PHROG | phrog_34294 | NA | unknown function |
| UHGV-0259903_62 | Structural annotation | PF00303, MF_01686, TIGR03283, COG0207 | NA | NA |
| UHGV-0259903_63 | KOfam | K00560 | thyA, TYMS; thymidylate synthase [EC:2.1.1.45] | NA |
| UHGV-0259903_63 | PHROG | phrog_160 | thymidylate synthase | DNA, RNA and nucleotide metabolism |
| UHGV-0259903_63 | UniRef90 | UniRef90_A0A316NZJ5 | Thymidylate synthase | NA |
| UHGV-0259903_63 | eggNOG-mapper | 37659.JNLN01000001_gene1135 | Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis | NA |
| UHGV-0259903_63 | Pfam | PF00303 | Thymidylate synthase | Thymidylat_synt |
| UHGV-0259903_63 | COG | COG0207 | Thymidylate synthase | NA |
| UHGV-0259903_63 | Structural annotation | PF00303, MF_01686, TIGR03283, COG0207 | NA | NA |
| UHGV-0259903_64 | KOfam | K02335 | polA; DNA polymerase I [EC:2.7.7.7] | NA |
| UHGV-0259903_64 | PHROG | phrog_17 | DNA polymerase | DNA, RNA and nucleotide metabolism |
| UHGV-0259903_64 | UniRef90 | UniRef90_A0A316P160 | DNA polymerase I (Fragment) | NA |
| UHGV-0259903_64 | eggNOG-mapper | 1340829.S5Y5D9_9CAUD | DNA polymerase family A | NA |
| UHGV-0259903_64 | PADLOC | drt-cluster58 | DRT | DRT |
| UHGV-0259903_64 | Pfam | PF03167 | Uracil DNA glycosylase superfamily | UDG |
| UHGV-0259903_64 | Pfam | PF01612 | 3'-5' exonuclease | DNA_pol_A_exo1 |
| UHGV-0259903_64 | Pfam | PF00476 | DNA polymerase family A | DNA_pol_A |
| UHGV-0259903_64 | Structural annotation | PF00476, PF03167, PF01612, MF_04101, MF_01956, NF004397, COG0749, COG1573 | NA | NA |
| UHGV-0259903_65 | KOfam | K16899 | addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-] | NA |
| UHGV-0259903_65 | PHROG | phrog_1218 | exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0259903_65 | UniRef90 | UniRef90_A0A5H2TJR6 | PDDEXK_1 domain-containing protein | NA |
| UHGV-0259903_65 | eggNOG-mapper | 706587.Desti_3464 | PD-(D/E)XK nuclease superfamily | NA |
| UHGV-0259903_65 | Pfam | PF12705 | PD-(D/E)XK nuclease superfamily | PDDEXK_1 |
| UHGV-0259903_65 | COG | COG2887 | RecB family exonuclease | NA |
| UHGV-0259903_65 | Structural annotation | PF12705, TIGR00372, COG2887 | NA | NA |
| UHGV-0259903_66 | Pfam | PF13479 | AAA domain | AAA_24 |