| UHGV-0067267_4 | KOfam | K01356 | lexA; repressor LexA [EC:3.4.21.88] | NA |
| UHGV-0067267_4 | PHROG | phrog_4 | transcriptional repressor | transcription regulation |
| UHGV-0067267_4 | UniRef90 | UniRef90_A0A073INQ6 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-0067267_4 | eggNOG-mapper | 2754.EH55_13060 | Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair | NA |
| UHGV-0067267_4 | PADLOC | retron_type_VI_hth_cluster2_1 | NA | Retron |
| UHGV-0067267_4 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0067267_4 | Pfam | PF00717 | Peptidase S24-like | Peptidase_S24 |
| UHGV-0067267_4 | COG | COG1974 | SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) | NA |
| UHGV-0067267_4 | Structural annotation | PF00717, PF01381, MF_00015, TIGR00498, COG2932 | NA | NA |
| UHGV-0067267_11 | PHROG | phrog_11269 | NA | unknown function |
| UHGV-0067267_11 | UniRef90 | UniRef90_A0A073IUV0 | PhageMetallopep domain-containing protein | NA |
| UHGV-0067267_11 | eggNOG-mapper | 457415.HMPREF1006_02821 | NA | NA |
| UHGV-0067267_11 | Pfam | PF18894 | Putative phage metallopeptidase | PhageMetallopep |
| UHGV-0067267_17 | PHROG | phrog_434 | RecE-like recombination exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0067267_17 | UniRef90 | UniRef90_A0A073IMY9 | YqaJ domain-containing protein | NA |
| UHGV-0067267_17 | eggNOG-mapper | 2754.EH55_07040 | YqaJ viral recombinase family | NA |
| UHGV-0067267_17 | Pfam | PF09588 | YqaJ-like viral recombinase domain | YqaJ |
| UHGV-0067267_17 | NCBIFam | TIGR03033.1 | putative phage-type endonuclease | NA |
| UHGV-0067267_17 | COG | COG5377 | Phage-related protein, predicted endonuclease | NA |
| UHGV-0067267_17 | Structural annotation | PF09588, MF_03030, TIGR03033, COG5377 | NA | NA |
| UHGV-0067267_20 | KOfam | K07455 | recT; recombination protein RecT | NA |
| UHGV-0067267_20 | PHROG | phrog_148 | RecT-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0067267_20 | UniRef90 | UniRef90_A0A845LLG7 | Recombination protein RecT | NA |
| UHGV-0067267_20 | eggNOG-mapper | 525255.HMPREF0077_0417 | RecT family | NA |
| UHGV-0067267_20 | Pfam | PF03837 | RecT family | RecT |
| UHGV-0067267_20 | NCBIFam | TIGR00616.1 | recombinase, phage RecT family | NA |
| UHGV-0067267_20 | COG | COG3723 | Recombinational DNA repair protein RecT | NA |
| UHGV-0067267_21 | PHROG | phrog_9474 | replication initiation protein | DNA, RNA and nucleotide metabolism |
| UHGV-0067267_21 | eggNOG-mapper | 411464.DESPIG_01302 | HNH endonuclease | NA |
| UHGV-0067267_21 | COG | COG1403 | 5-methylcytosine-specific restriction endonuclease McrA | NA |
| UHGV-0067267_22 | PHROG | phrog_10105 | NA | unknown function |
| UHGV-0067267_22 | UniRef90 | UniRef90_UPI0004BA3A99 | NA | NA |
| UHGV-0067267_22 | eggNOG-mapper | 2754.EH55_07025 | NA | NA |
| UHGV-0067267_23 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-0067267_23 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0067267_23 | UniRef90 | UniRef90_D2Z2X8 | Single-stranded DNA-binding protein | NA |
| UHGV-0067267_23 | eggNOG-mapper | 469381.Dpep_0164 | Single-stranded DNA-binding protein | NA |
| UHGV-0067267_23 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-0067267_23 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-0067267_23 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-0067267_23 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-0067267_23 | Structural annotation | PF00436, MF_00984, NF005241, COG0629 | NA | NA |
| UHGV-0067267_28 | PHROG | phrog_2999 | NA | unknown function |
| UHGV-0067267_32 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-0067267_32 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-0067267_32 | UniRef90 | UniRef90_A0A1Y4GD55 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-0067267_32 | eggNOG-mapper | 1286093.C266_11335 | Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family | NA |
| UHGV-0067267_32 | PADLOC | MTase_II_00020 | Type II methyltransferase | RM |
| UHGV-0067267_32 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-0067267_32 | NCBIFam | TIGR00675.1 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-0067267_32 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-0067267_32 | Structural annotation | PF00145, MF_00351, TIGR00675, COG0270 | NA | NA |
| UHGV-0067267_33 | KOfam | K00390 | cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] | NA |
| UHGV-0067267_33 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-0067267_33 | UniRef90 | UniRef90_A0A1B2I384 | PAPS_reduct domain-containing protein | NA |
| UHGV-0067267_33 | eggNOG-mapper | 2754.EH55_08570 | sulfate reduction | NA |
| UHGV-0067267_33 | PADLOC | BrxP_00001 | BrxP | BREX |
| UHGV-0067267_33 | Pfam | PF01507 | Phosphoadenosine phosphosulfate reductase family | PAPS_reduct |
| UHGV-0067267_33 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-0067267_33 | Structural annotation | PF01507, MF_00063, NF010369, COG0175 | NA | NA |
| UHGV-0067267_34 | eggNOG-mapper | 1231377.C426_1976 | DNA restriction-modification system | NA |
| UHGV-0067267_34 | COG | COG0827 | Adenine-specific DNA N6-methylase | NA |
| UHGV-0067267_37 | PHROG | phrog_801 | endolysin; inhibits RNA polymerase | lysis |
| UHGV-0067267_37 | UniRef90 | UniRef90_UPI001E611622 | GNAT family N-acetyltransferase | NA |
| UHGV-0067267_37 | eggNOG-mapper | 1094561.MEI_01479 | NA | NA |
| UHGV-0067267_37 | Pfam | PF18909 | dATP/dGTP diphosphohydrolase, N-terminal | dGTP_diPhyd_N |
| UHGV-0067267_37 | Pfam | PF01503 | Phosphoribosyl-ATP pyrophosphohydrolase | PRA-PH |
| UHGV-0067267_42 | PHROG | phrog_824 | NA | unknown function |
| UHGV-0067267_42 | UniRef90 | UniRef90_A0A1Y4GFX6 | VRR-NUC domain-containing protein | NA |
| UHGV-0067267_42 | eggNOG-mapper | 767434.Fraau_0982 | VRR-NUC domain | NA |
| UHGV-0067267_42 | Pfam | PF08774 | VRR-NUC domain | VRR_NUC |
| UHGV-0067267_42 | Structural annotation | PF08774 | NA | NA |
| UHGV-0067267_44 | KOfam | K06400 | spoIVCA; site-specific DNA recombinase | NA |
| UHGV-0067267_44 | PHROG | phrog_95 | integrase | integration and excision |
| UHGV-0067267_44 | UniRef90 | UniRef90_A0A497A8R4 | Recombinase family protein | NA |
| UHGV-0067267_44 | eggNOG-mapper | 243164.DET0155 | Recombinase zinc beta ribbon domain | NA |
| UHGV-0067267_44 | Pfam | PF00239 | Resolvase, N terminal domain | Resolvase |
| UHGV-0067267_44 | Pfam | PF07508 | Recombinase | Recombinase |
| UHGV-0067267_44 | COG | COG1961 | Site-specific DNA recombinase SpoIVCA/DNA invertase PinE | NA |
| UHGV-0067267_44 | Structural annotation | PF07508, PF00239, NF041201, COG1961 | NA | NA |
| UHGV-0067267_48 | KOfam | K07474 | xtmA; phage terminase small subunit | NA |
| UHGV-0067267_48 | PHROG | phrog_51 | terminase small subunit | head and packaging |
| UHGV-0067267_48 | UniRef90 | UniRef90_UPI001C648338 | terminase small subunit | NA |
| UHGV-0067267_48 | eggNOG-mapper | 1268072.PSAB_06050 | terminase small subunit | NA |
| UHGV-0067267_48 | Pfam | PF03592 | Terminase small subunit | Terminase_2 |
| UHGV-0067267_48 | COG | COG3728 | Phage terminase, small subunit | NA |
| UHGV-0067267_50 | PHROG | phrog_38 | terminase large subunit | head and packaging |
| UHGV-0067267_50 | UniRef90 | UniRef90_A0A7X7II02 | Terminase_6C domain-containing protein | NA |
| UHGV-0067267_50 | eggNOG-mapper | 883156.HMPREF9282_00550 | Terminase RNaseH-like domain | NA |
| UHGV-0067267_50 | Pfam | PF17289 | Terminase RNaseH-like domain | Terminase_6C |
| UHGV-0067267_50 | NCBIFam | TIGR01630.1 | phage terminase large subunit | NA |
| UHGV-0067267_50 | COG | COG5362 | Phage terminase large subunit | NA |
| UHGV-0067267_51 | PHROG | phrog_1216 | portal protein | head and packaging |
| UHGV-0067267_51 | UniRef90 | UniRef90_A0A7X7EMS4 | DOD-type homing endonuclease domain-containing protein | NA |
| UHGV-0067267_51 | eggNOG-mapper | 608538.HTH_0544 | translation initiation factor activity | NA |
| UHGV-0067267_51 | COG | COG3064 | Membrane protein TolA involved in colicin uptake | NA |
| UHGV-0067267_51 | Structural annotation | PF12236, MF_04120, TIGR01542, COG4695 | NA | NA |
| UHGV-0067267_56 | PHROG | phrog_23773 | NA | unknown function |
| UHGV-0067267_56 | eggNOG-mapper | 484770.UFO1_3918 | UMP catabolic process | NA |
| UHGV-0067267_56 | COG | COG0647 | Ribonucleotide monophosphatase NagD, HAD superfamily | NA |
| UHGV-0067267_59 | PHROG | phrog_1357 | major head protein | head and packaging |
| UHGV-0067267_59 | UniRef90 | UniRef90_A0A7X7EM01 | N4-gp56 family major capsid protein | NA |
| UHGV-0067267_59 | eggNOG-mapper | 1121447.JONL01000007_gene1395 | NA | NA |
| UHGV-0067267_59 | NCBIFam | TIGR04387.1 | N4-gp56 family major capsid protein | NA |
| UHGV-0067267_59 | Structural annotation | PF13252, MF_04119, TIGR04387, COG4653 | NA | NA |
| UHGV-0067267_61 | Pfam | PF02037 | SAP domain | SAP |
| UHGV-0067267_65 | eggNOG-mapper | 1123288.SOV_4c02720 | NA | NA |
| UHGV-0067267_66 | PHROG | phrog_31 | baseplate hub protein Tal | tail |
| UHGV-0067267_66 | UniRef90 | UniRef90_A0A010YT80 | NA | NA |
| UHGV-0067267_66 | eggNOG-mapper | 2754.EH55_06800 | cellulase activity | NA |
| UHGV-0067267_66 | Pfam | PF09327 | NA | DUF1983 |
| UHGV-0067267_66 | COG | COG0542 | ATP-dependent Clp protease, ATP-binding subunit ClpA | NA |
| UHGV-0067267_69 | PHROG | phrog_1084 | NA | unknown function |
| UHGV-0067267_70 | PHROG | phrog_972 | tail fiber protein proximal subunit | tail |
| UHGV-0067267_70 | eggNOG-mapper | 1235800.C819_00472 | NA | NA |
| UHGV-0067267_70 | Pfam | PF19789 | NA | DUF6273 |
| UHGV-0067267_71 | eggNOG-mapper | 665950.HMPREF1025_01558 | NA | NA |
| UHGV-0067267_71 | Structural annotation | PF05635, TIGR02436 | NA | NA |
| UHGV-0067267_72 | KOfam | K00986 | ltrA; RNA-directed DNA polymerase [EC:2.7.7.49] | NA |
| UHGV-0067267_72 | PHROG | phrog_1423 | Reverse transcriptase | DNA, RNA and nucleotide metabolism |
| UHGV-0067267_72 | UniRef90 | UniRef90_A0A509ENF1 | Reverse transcriptase | NA |
| UHGV-0067267_72 | eggNOG-mapper | 1410650.JHWL01000003_gene2820 | Reverse transcriptase | NA |
| UHGV-0067267_72 | PADLOC | icity0040 | RT (reverse transcriptase) | CRISPR-CAS |
| UHGV-0067267_72 | Pfam | PF00078 | Reverse transcriptase (RNA-dependent DNA polymerase) | RVT_1 |
| UHGV-0067267_72 | COG | COG3344 | Retron-type reverse transcriptase | NA |
| UHGV-0067267_72 | Structural annotation | PF00078, MF_01390, TIGR04416, COG3344 | NA | NA |
| UHGV-0067267_73 | KOfam | K22918 | ttsA; typhoid toxin secretion A | NA |
| UHGV-0067267_73 | PHROG | phrog_315 | endolysin | lysis |
| UHGV-0067267_73 | UniRef90 | UniRef90_A0A1Y4GG13 | PG_binding_3 domain-containing protein | NA |
| UHGV-0067267_73 | eggNOG-mapper | 469381.Dpep_2452 | Predicted Peptidoglycan domain | NA |
| UHGV-0067267_73 | Pfam | PF05838 | Glycosyl hydrolase 108 | Glyco_hydro_108 |
| UHGV-0067267_73 | Pfam | PF09374 | Predicted Peptidoglycan domain | PG_binding_3 |
| UHGV-0067267_73 | COG | COG3926 | Lysozyme family protein | NA |
| UHGV-0067267_73 | Structural annotation | PF05838, PF09374, NF040573, COG3926 | NA | NA |
| UHGV-0067267_75 | PHROG | phrog_3427 | holin | lysis |
| UHGV-0067267_75 | UniRef90 | UniRef90_UPI0004B141F7 | 3TM-type holin | NA |
| UHGV-0067267_75 | eggNOG-mapper | 1201293.AKXQ01000048_gene1286 | Holin of 3TMs, for gene-transfer release | NA |
| UHGV-0067267_75 | Pfam | PF11351 | Holin of 3TMs, for gene-transfer release | GTA_holin_3TM |
| UHGV-0067267_80 | PHROG | phrog_5143 | NA | unknown function |
| UHGV-0067267_80 | eggNOG-mapper | 421052.F945_01943 | lytic transglycosylase activity | NA |
| UHGV-0067267_80 | Pfam | PF18763 | ddrB-like ParB superfamily domain | ddrB-ParB |
| UHGV-0067267_80 | COG | COG0741 | Soluble lytic murein transglycosylase or regulatory protein s ( may contain LysM/invasin domain) | NA |