| UHGV-0042713_1 | KOfam | K14059 | int; integrase | NA |
| UHGV-0042713_1 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-0042713_1 | UniRef90 | UniRef90_UPI0013EDD93A | site-specific integrase | NA |
| UHGV-0042713_1 | eggNOG-mapper | 665942.HMPREF1022_00104 | Phage integrase family | NA |
| UHGV-0042713_1 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-0042713_1 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-0042713_1 | Structural annotation | PF00589, PF13495, PF02920, MF_01808, TIGR02225, COG4974 | NA | NA |
| UHGV-0042713_3 | KOfam | K07741 | antB; anti-repressor protein | NA |
| UHGV-0042713_3 | PHROG | phrog_130 | anti-repressor Ant | transcription regulation |
| UHGV-0042713_3 | UniRef90 | UniRef90_G1UND3 | Bro-N domain-containing protein | NA |
| UHGV-0042713_3 | eggNOG-mapper | 665942.HMPREF1022_00106 | Phage antirepressor protein KilAC domain | NA |
| UHGV-0042713_3 | Pfam | PF02498 | BRO family, N-terminal domain | Bro-N |
| UHGV-0042713_3 | Pfam | PF03374 | Phage antirepressor protein KilAC domain | ANT |
| UHGV-0042713_3 | COG | COG3617 | Prophage antirepressor | NA |
| UHGV-0042713_3 | Structural annotation | PF03374, PF02498, TIGR02681, COG3645 | NA | NA |
| UHGV-0042713_4 | eggNOG-mapper | 665942.HMPREF1022_00107 | NA | NA |
| UHGV-0042713_5 | Pfam | PF14354 | Restriction alleviation protein Lar | Lar_restr_allev |
| UHGV-0042713_6 | PHROG | phrog_874 | NA | unknown function |
| UHGV-0042713_6 | eggNOG-mapper | 665942.HMPREF1022_00109 | NA | NA |
| UHGV-0042713_6 | Structural annotation | PF04266, MF_00684, NF003443, COG4405 | NA | NA |
| UHGV-0042713_7 | PHROG | phrog_954 | DNA methyltransferase | other |
| UHGV-0042713_7 | UniRef90 | UniRef90_UPI00038F7407 | class I SAM-dependent methyltransferase | NA |
| UHGV-0042713_7 | eggNOG-mapper | 665942.HMPREF1022_00110 | Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA | NA |
| UHGV-0042713_7 | PADLOC | MTase_II_00074 | Type II methyltransferase | RM |
| UHGV-0042713_7 | Pfam | PF08241 | Methyltransferase domain | Methyltransf_11 |
| UHGV-0042713_7 | COG | COG1092 | 23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI | NA |
| UHGV-0042713_7 | Structural annotation | PF01170, MF_01057, TIGR00446, COG4123 | NA | NA |
| UHGV-0042713_12 | PHROG | phrog_18900 | NA | unknown function |
| UHGV-0042713_12 | eggNOG-mapper | 1304872.JAGC01000005_gene1616 | NA | NA |
| UHGV-0042713_12 | Structural annotation | PF11535, MF_00948, NF008636, COG4568 | NA | NA |
| UHGV-0042713_13 | PHROG | phrog_253 | Mu Gam-like end protection | DNA, RNA and nucleotide metabolism |
| UHGV-0042713_13 | UniRef90 | UniRef90_UPI0004260CAC | siphovirus Gp157 family protein | NA |
| UHGV-0042713_13 | eggNOG-mapper | 665942.HMPREF1022_00116 | PFAM Gp157 family protein | NA |
| UHGV-0042713_13 | Pfam | PF05565 | Siphovirus Gp157 | Sipho_Gp157 |
| UHGV-0042713_13 | Structural annotation | PF05565, NF002139 | NA | NA |
| UHGV-0042713_14 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-0042713_14 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0042713_14 | UniRef90 | UniRef90_G1UNE4 | Single-stranded DNA-binding protein | NA |
| UHGV-0042713_14 | eggNOG-mapper | 665942.HMPREF1022_00117 | PFAM single-strand binding protein Primosomal replication protein n | NA |
| UHGV-0042713_14 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-0042713_14 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-0042713_14 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-0042713_14 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-0042713_14 | Structural annotation | PF00436, MF_00984, NF005241, COG0629 | NA | NA |
| UHGV-0042713_15 | PHROG | phrog_2324 | Erf-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0042713_15 | UniRef90 | UniRef90_A0A562PPD0 | ERF superfamily protein | NA |
| UHGV-0042713_15 | eggNOG-mapper | 665942.HMPREF1022_00118 | ERF superfamily | NA |
| UHGV-0042713_15 | Pfam | PF04404 | ERF superfamily | ERF |
| UHGV-0042713_15 | Structural annotation | PF04404 | NA | NA |
| UHGV-0042713_16 | eggNOG-mapper | 665942.HMPREF1022_00119 | NA | NA |
| UHGV-0042713_17 | eggNOG-mapper | 457398.HMPREF0326_02545 | NA | NA |
| UHGV-0042713_18 | KOfam | K21919 | KCTD9; BTB/POZ domain-containing protein KCTD9 | NA |
| UHGV-0042713_18 | PHROG | phrog_923 | NA | unknown function |
| UHGV-0042713_18 | eggNOG-mapper | 665942.HMPREF1022_00121 | Pentapeptide repeats (8 copies) | NA |
| UHGV-0042713_18 | Pfam | PF00805 | Pentapeptide repeats (8 copies) | Pentapeptide |
| UHGV-0042713_18 | NCBIFam | NF038108.1 | Cys-every-fifth RiPP peptide CefA | NA |
| UHGV-0042713_18 | COG | COG1357 | NA | NA |
| UHGV-0042713_18 | Structural annotation | PF13599, NF011744, COG1357 | NA | NA |
| UHGV-0042713_20 | PHROG | phrog_19458 | primase | DNA, RNA and nucleotide metabolism |
| UHGV-0042713_20 | eggNOG-mapper | 665942.HMPREF1022_00123 | nucleotidyltransferase activity | NA |
| UHGV-0042713_20 | COG | COG4227 | Antirestriction protein ArdC | NA |
| UHGV-0042713_24 | KOfam | K01356 | lexA; repressor LexA [EC:3.4.21.88] | NA |
| UHGV-0042713_24 | PHROG | phrog_4 | transcriptional repressor | transcription regulation |
| UHGV-0042713_24 | UniRef90 | UniRef90_G1UNF4 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-0042713_24 | eggNOG-mapper | 665942.HMPREF1022_00127 | Peptidase S24-like | NA |
| UHGV-0042713_24 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0042713_24 | Pfam | PF00717 | Peptidase S24-like | Peptidase_S24 |
| UHGV-0042713_24 | COG | COG2932 | Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains | NA |
| UHGV-0042713_24 | Structural annotation | PF00717, MF_00015, TIGR00498, COG2932 | NA | NA |
| UHGV-0042713_26 | UniRef90 | UniRef90_UPI001C3B8A40 | XRE family transcriptional regulator | NA |
| UHGV-0042713_26 | eggNOG-mapper | 665942.HMPREF1022_00130 | NA | NA |
| UHGV-0042713_26 | Pfam | PF06892 | Phage regulatory protein CII (CP76) | Phage_CP76 |
| UHGV-0042713_28 | PHROG | phrog_2514 | DnaD-like helicase loader | DNA, RNA and nucleotide metabolism |
| UHGV-0042713_28 | UniRef90 | UniRef90_UPI001D09F98A | helix-turn-helix domain-containing protein | NA |
| UHGV-0042713_28 | eggNOG-mapper | 665942.HMPREF1022_00132 | DnaD domain protein | NA |
| UHGV-0042713_28 | COG | COG3935 | DNA replication protein DnaD | NA |
| UHGV-0042713_28 | Structural annotation | PF07106, TIGR01610, COG0735 | NA | NA |
| UHGV-0042713_29 | UniRef90 | UniRef90_A0A6J5QW72 | VRR-NUC domain containing protein | NA |
| UHGV-0042713_29 | eggNOG-mapper | 665942.HMPREF1022_00133 | NA | NA |
| UHGV-0042713_31 | eggNOG-mapper | 665942.HMPREF1022_00134 | NA | NA |
| UHGV-0042713_32 | PHROG | phrog_24780 | NA | unknown function |
| UHGV-0042713_32 | UniRef90 | UniRef90_G1UNG2 | Pesticin domain-containing protein | NA |
| UHGV-0042713_32 | eggNOG-mapper | 665942.HMPREF1022_00135 | Bacterial toxin homologue of phage lysozyme, C-term | NA |
| UHGV-0042713_32 | Pfam | PF16754 | Bacterial toxin homologue of phage lysozyme, C-term | Pesticin |
| UHGV-0042713_32 | COG | COG3409 | Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases | NA |
| UHGV-0042713_32 | Structural annotation | PF16754, MF_04136, COG3772 | NA | NA |
| UHGV-0042713_33 | eggNOG-mapper | 457398.HMPREF0326_02527 | NA | NA |
| UHGV-0042713_34 | eggNOG-mapper | 665942.HMPREF1022_00137 | NA | NA |
| UHGV-0042713_35 | PHROG | phrog_2412 | NA | unknown function |
| UHGV-0042713_35 | UniRef90 | UniRef90_A0A380K8U5 | NA | NA |
| UHGV-0042713_35 | eggNOG-mapper | 665942.HMPREF1022_00138 | NA | NA |
| UHGV-0042713_36 | PHROG | phrog_5902 | NA | unknown function |
| UHGV-0042713_36 | UniRef90 | UniRef90_UPI001C01FE26 | terminase | NA |
| UHGV-0042713_36 | eggNOG-mapper | 665942.HMPREF1022_00139 | A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD | NA |
| UHGV-0042713_36 | COG | COG0507 | ATPase/5'-3' helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) | NA |
| UHGV-0042713_36 | Structural annotation | PF03237, PF20441, MF_04145, TIGR01547, COG1783 | NA | NA |
| UHGV-0042713_37 | UniRef90 | UniRef90_UPI0001E12D4C | GNAT family N-acetyltransferase | NA |
| UHGV-0042713_37 | eggNOG-mapper | 665942.HMPREF1022_00140 | NA | NA |
| UHGV-0042713_38 | PHROG | phrog_332 | head-tail adaptor | connector |
| UHGV-0042713_38 | UniRef90 | UniRef90_UPI0001E12D4B | portal protein | NA |
| UHGV-0042713_38 | eggNOG-mapper | 665942.HMPREF1022_00141 | Bacteriophage head to tail connecting protein | NA |
| UHGV-0042713_38 | Pfam | PF12236 | Bacteriophage head to tail connecting protein | Head-tail_con |
| UHGV-0042713_38 | Structural annotation | PF12236, MF_04120, TIGR01538, COG4695 | NA | NA |
| UHGV-0042713_40 | PHROG | phrog_458 | protease | other |
| UHGV-0042713_40 | UniRef90 | UniRef90_A0A6F8VD24 | Phage endoprotease | NA |
| UHGV-0042713_40 | eggNOG-mapper | 665942.HMPREF1022_00143 | NA | NA |
| UHGV-0042713_41 | PHROG | phrog_212 | major head protein | head and packaging |
| UHGV-0042713_41 | UniRef90 | UniRef90_A0A6J5P2C9 | Major capsid protein | NA |
| UHGV-0042713_41 | eggNOG-mapper | 665942.HMPREF1022_00144 | NA | NA |
| UHGV-0042713_41 | Pfam | PF20911 | Major capsid protein GP7 | GP7 |
| UHGV-0042713_41 | Structural annotation | PF20911, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0042713_42 | eggNOG-mapper | 665942.HMPREF1022_00145 | NA | NA |
| UHGV-0042713_42 | Pfam | PF21190 | Bbp16 | Bbp16 |
| UHGV-0042713_42 | Structural annotation | PF21190 | NA | NA |
| UHGV-0042713_43 | PHROG | phrog_394 | tail protein | tail |
| UHGV-0042713_43 | eggNOG-mapper | 665942.HMPREF1022_00146 | NA | NA |
| UHGV-0042713_43 | Structural annotation | PF17212 | NA | NA |
| UHGV-0042713_44 | PHROG | phrog_1640 | tail protein | tail |
| UHGV-0042713_44 | eggNOG-mapper | 665942.HMPREF1022_00147 | NA | NA |
| UHGV-0042713_45 | UniRef90 | UniRef90_A0A0X8JK75 | Phage tail protein | NA |
| UHGV-0042713_45 | eggNOG-mapper | 665942.HMPREF1022_00148 | NA | NA |
| UHGV-0042713_45 | Structural annotation | PF16778 | NA | NA |
| UHGV-0042713_46 | PHROG | phrog_376 | tail protein | tail |
| UHGV-0042713_46 | UniRef90 | UniRef90_H8FP71 | Bbp13 | NA |
| UHGV-0042713_46 | eggNOG-mapper | 665942.HMPREF1022_00149 | NA | NA |
| UHGV-0042713_46 | Structural annotation | PF11134, MF_00923, TIGR03300, COG2706 | NA | NA |
| UHGV-0042713_47 | UniRef90 | UniRef90_UPI0001E12C04 | GNAT family N-acetyltransferase | NA |
| UHGV-0042713_47 | eggNOG-mapper | 665942.HMPREF1022_00150 | NA | NA |
| UHGV-0042713_47 | Structural annotation | PF00583, MF_02210, NF007530, COG0456 | NA | NA |
| UHGV-0042713_48 | PHROG | phrog_418 | internal virion protein | head and packaging |
| UHGV-0042713_48 | eggNOG-mapper | 665942.HMPREF1022_00151 | NA | NA |
| UHGV-0042713_48 | Structural annotation | PF07321, NF041271 | NA | NA |
| UHGV-0042713_49 | eggNOG-mapper | 665942.HMPREF1022_00152 | NA | NA |
| UHGV-0042713_50 | UniRef90 | UniRef90_G1UNI0 | LPD3 domain-containing protein | NA |
| UHGV-0042713_50 | eggNOG-mapper | 665942.HMPREF1022_00153 | methylase | NA |
| UHGV-0042713_50 | Pfam | PF18798 | Large polyvalent protein-associated domain 3 | LPD3 |
| UHGV-0042713_50 | COG | COG0553 | Superfamily II DNA or RNA helicase, SNF2 family | NA |
| UHGV-0042713_51 | PHROG | phrog_684 | virion structural protein | head and packaging |
| UHGV-0042713_51 | UniRef90 | UniRef90_A0A345BQW7 | Structural protein | NA |
| UHGV-0042713_51 | eggNOG-mapper | 665942.HMPREF1022_00154 | NA | NA |
| UHGV-0042713_56 | UniRef90 | UniRef90_UPI001D0ADCD9 | Rha family transcriptional regulator | NA |
| UHGV-0042713_56 | eggNOG-mapper | 665942.HMPREF1022_00158 | NA | NA |
| UHGV-0042713_56 | Structural annotation | PF09669, TIGR02681, COG3646 | NA | NA |
| UHGV-0042713_57 | PHROG | phrog_2127 | anti-repressor | transcription regulation |
| UHGV-0042713_57 | UniRef90 | UniRef90_G1UNI6 | Bro-N domain-containing protein | NA |
| UHGV-0042713_57 | eggNOG-mapper | 665942.HMPREF1022_00159 | ORF6C domain | NA |
| UHGV-0042713_57 | Pfam | PF02498 | BRO family, N-terminal domain | Bro-N |
| UHGV-0042713_57 | Pfam | PF10552 | ORF6C domain | ORF6C |
| UHGV-0042713_57 | COG | COG3617 | Prophage antirepressor | NA |
| UHGV-0042713_57 | Structural annotation | PF10547, NF033622, COG3617 | NA | NA |
| UHGV-0042713_59 | UniRef90 | UniRef90_G1UNI7 | HNHc domain-containing protein | NA |
| UHGV-0042713_59 | eggNOG-mapper | 665942.HMPREF1022_00160 | HNH nucleases | NA |
| UHGV-0042713_59 | Pfam | PF01844 | HNH endonuclease | HNH |
| UHGV-0042713_60 | UniRef90 | UniRef90_UPI000556A5B4 | type II toxin-antitoxin system HicA family toxin | NA |
| UHGV-0042713_60 | eggNOG-mapper | 290317.Cpha266_1441 | mRNA binding | NA |
| UHGV-0042713_60 | Pfam | PF07927 | HicA toxin of bacterial toxin-antitoxin, | HicA_toxin |
| UHGV-0042713_60 | COG | COG1724 | Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family | NA |
| UHGV-0042713_61 | UniRef90 | UniRef90_UPI000AC3D3A7 | type II toxin-antitoxin system HicB family antitoxin | NA |
| UHGV-0042713_61 | eggNOG-mapper | 665942.HMPREF1022_00161 | PFAM Uncharacterised protein family UPF0150 | NA |
| UHGV-0042713_61 | COG | COG1598 | Antitoxin component HicB of the HicAB toxin-antitoxin system | NA |