| UHGV-1545254_2 | KOfam | K07726 | K07726; putative transcriptional regulator | NA |
| UHGV-1545254_2 | PHROG | phrog_2104 | NA | unknown function |
| UHGV-1545254_2 | UniRef90 | UniRef90_A0A414P8A6 | Helix-turn-helix domain-containing protein | NA |
| UHGV-1545254_2 | eggNOG-mapper | 471875.RUMLAC_02311 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-1545254_2 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1545254_2 | COG | COG2944 | DNA-binding transcriptional regulator YiaG, XRE-type HTH domain | NA |
| UHGV-1545254_2 | Structural annotation | PF15731, NF007481, COG2944 | NA | NA |
| UHGV-1545254_3 | eggNOG-mapper | 1226322.HMPREF1545_00079 | NA | NA |
| UHGV-1545254_4 | eggNOG-mapper | 476272.RUMHYD_01772 | NA | NA |
| UHGV-1545254_4 | Structural annotation | PF12510 | NA | NA |
| UHGV-1545254_5 | PHROG | phrog_20016 | NA | unknown function |
| UHGV-1545254_5 | UniRef90 | UniRef90_A0A285PT46 | Tumour necrosis factor-like domain | NA |
| UHGV-1545254_5 | eggNOG-mapper | 1226322.HMPREF1545_00077 | NA | NA |
| UHGV-1545254_5 | Structural annotation | PF18573, NF033147 | NA | NA |
| UHGV-1545254_6 | PHROG | phrog_16490 | NA | unknown function |
| UHGV-1545254_6 | eggNOG-mapper | 1408437.JNJN01000043_gene803 | NA | NA |
| UHGV-1545254_7 | PHROG | phrog_22984 | NA | unknown function |
| UHGV-1545254_8 | PHROG | phrog_21718 | NA | unknown function |
| UHGV-1545254_8 | eggNOG-mapper | 397290.C810_05210 | NA | NA |
| UHGV-1545254_9 | PHROG | phrog_3754 | NA | unknown function |
| UHGV-1545254_9 | eggNOG-mapper | 476272.RUMHYD_01764 | NA | NA |
| UHGV-1545254_10 | UniRef90 | UniRef90_A0A8D9PDT6 | Transcriptional regulatory protein | NA |
| UHGV-1545254_11 | PHROG | phrog_608 | holin | lysis |
| UHGV-1545254_11 | UniRef90 | UniRef90_UPI0019604BA7 | phage holin, LLH family | NA |
| UHGV-1545254_11 | eggNOG-mapper | 1121472.AQWN01000009_gene420 | Bacteriophage holin of superfamily 6 (Holin_LLH) | NA |
| UHGV-1545254_11 | Pfam | PF09682 | Bacteriophage holin of superfamily 6 (Holin_LLH) | Phage_holin_6_1 |
| UHGV-1545254_11 | Structural annotation | PF09682, TIGR01673 | NA | NA |
| UHGV-1545254_12 | PHROG | phrog_37604 | NA | unknown function |
| UHGV-1545254_12 | eggNOG-mapper | 585501.HMPREF6123_0817 | NA | NA |
| UHGV-1545254_13 | KOfam | K07273 | acm; lysozyme | NA |
| UHGV-1545254_13 | PHROG | phrog_291 | endolysin | lysis |
| UHGV-1545254_13 | UniRef90 | UniRef90_A0A3D2G0D9 | Cpl-7 domain-containing protein | NA |
| UHGV-1545254_13 | eggNOG-mapper | 877415.JNJQ01000013_gene314 | Glycosyl hydrolases family 25 | NA |
| UHGV-1545254_13 | Pfam | PF01183 | Glycosyl hydrolases family 25 | Glyco_hydro_25 |
| UHGV-1545254_13 | Pfam | PF08230 | CW_7 repeat | CW_7 |
| UHGV-1545254_13 | COG | COG3757 | Lyzozyme M1 (1,4-beta-N-acetylmuramidase), GH25 family | NA |
| UHGV-1545254_13 | Structural annotation | PF01183, COG3757 | NA | NA |
| UHGV-1545254_15 | PHROG | phrog_9534 | head protein | head and packaging |
| UHGV-1545254_15 | UniRef90 | UniRef90_UPI0015C5CE46 | tail fiber protein | NA |
| UHGV-1545254_15 | eggNOG-mapper | 748224.HMPREF9436_00702 | COG NOG18825 non supervised orthologous group | NA |
| UHGV-1545254_16 | PHROG | phrog_538 | minor tail protein | tail |
| UHGV-1545254_16 | UniRef90 | UniRef90_UPI001C113FEF | siphovirus ReqiPepy6 Gp37-like family protein | NA |
| UHGV-1545254_16 | eggNOG-mapper | 931626.Awo_c30930 | Siphovirus ReqiPepy6 Gp37-like protein | NA |
| UHGV-1545254_16 | Pfam | PF14594 | Siphovirus ReqiPepy6 Gp37-like protein | Sipho_Gp37 |
| UHGV-1545254_16 | Structural annotation | PF14594, TIGR01665, COG4926 | NA | NA |
| UHGV-1545254_17 | PHROG | phrog_36410 | NA | unknown function |
| UHGV-1545254_17 | UniRef90 | UniRef90_UPI001C0FCFFA | phage tail family protein | NA |
| UHGV-1545254_17 | eggNOG-mapper | 411471.SUBVAR_06982 | Phage tail protein | NA |
| UHGV-1545254_17 | Structural annotation | PF16774, TIGR01633, COG4722 | NA | NA |
| UHGV-1545254_18 | PHROG | phrog_23464 | NA | unknown function |
| UHGV-1545254_18 | eggNOG-mapper | 665950.HMPREF1025_02660 | phage tail tape measure protein | NA |
| UHGV-1545254_18 | COG | COG5283 | Phage-related tail protein | NA |
| UHGV-1545254_18 | Structural annotation | PF20155, MF_04138 | NA | NA |
| UHGV-1545254_20 | PHROG | phrog_885 | major tail protein | tail |
| UHGV-1545254_20 | UniRef90 | UniRef90_A0A843J9F0 | Ig-like domain-containing protein | NA |
| UHGV-1545254_20 | eggNOG-mapper | 1504822.CCNO01000012_gene492 | NA | NA |
| UHGV-1545254_20 | Structural annotation | PF06488, TIGR01603, COG5437 | NA | NA |
| UHGV-1545254_21 | Structural annotation | PF11367 | NA | NA |
| UHGV-1545254_22 | PHROG | phrog_17977 | NA | unknown function |
| UHGV-1545254_22 | Pfam | PF05521 | Phage head-tail joining protein | Phage_H_T_join |
| UHGV-1545254_22 | NCBIFam | TIGR01563.1 | phage head closure protein | NA |
| UHGV-1545254_22 | Structural annotation | PF05521, TIGR01563, COG5614 | NA | NA |
| UHGV-1545254_24 | PHROG | phrog_267 | major head protein | head and packaging |
| UHGV-1545254_24 | UniRef90 | UniRef90_A0A3Q9B9E4 | P22 coat protein-protein 5 domain protein | NA |
| UHGV-1545254_24 | eggNOG-mapper | 877414.ATWA01000001_gene909 | P22 coat protein-protein 5 domain protein | NA |
| UHGV-1545254_24 | Pfam | PF19821 | Phage capsid protein | Phage_capsid_2 |
| UHGV-1545254_24 | Structural annotation | PF19821, MF_04119, TIGR04387, COG4653 | NA | NA |
| UHGV-1545254_25 | UniRef90 | UniRef90_A0A6B9SU02 | Fibronectin autolysin | NA |
| UHGV-1545254_25 | Structural annotation | PF06810 | NA | NA |
| UHGV-1545254_26 | PHROG | phrog_5 | tail completion or Neck1 protein | connector |
| UHGV-1545254_26 | UniRef90 | UniRef90_UPI000691EB78 | HK97 gp10 family phage protein | NA |
| UHGV-1545254_26 | eggNOG-mapper | 1280689.AUJC01000007_gene3313 | Bacteriophage HK97-gp10, putative tail-component | NA |
| UHGV-1545254_26 | Pfam | PF04883 | Bacteriophage HK97-gp10, putative tail-component | HK97-gp10_like |
| UHGV-1545254_26 | Structural annotation | PF20039, TIGR01725, COG5005 | NA | NA |
| UHGV-1545254_27 | PHROG | phrog_2468 | head morphogenesis | head and packaging |
| UHGV-1545254_27 | UniRef90 | UniRef90_A0A4D7AUA1 | Phage head morphogenesis protein | NA |
| UHGV-1545254_27 | eggNOG-mapper | 1504822.CCNO01000013_gene286 | cell adhesion | NA |
| UHGV-1545254_27 | Pfam | PF04233 | Phage Mu protein F like protein | Phage_Mu_F |
| UHGV-1545254_27 | COG | COG2369 | NA | NA |
| UHGV-1545254_27 | Structural annotation | PF04233, TIGR01641, COG2369 | NA | NA |
| UHGV-1545254_28 | PHROG | phrog_64 | portal protein | head and packaging |
| UHGV-1545254_28 | UniRef90 | UniRef90_UPI0018A8A301 | phage portal protein | NA |
| UHGV-1545254_28 | eggNOG-mapper | 673376.F2VHW1_9CAUD | Phage portal protein, SPP1 Gp6-like | NA |
| UHGV-1545254_28 | Pfam | PF05133 | Phage portal protein, SPP1 Gp6-like | Phage_prot_Gp6 |
| UHGV-1545254_28 | Structural annotation | PF05133, MF_04120, TIGR01538, COG3567 | NA | NA |
| UHGV-1545254_29 | PHROG | phrog_38 | terminase large subunit | head and packaging |
| UHGV-1545254_29 | UniRef90 | UniRef90_UPI00166CA12B | terminase family protein | NA |
| UHGV-1545254_29 | eggNOG-mapper | 1140001.I571_01829 | NA | NA |
| UHGV-1545254_29 | Structural annotation | PF17289, PF05876, MF_04147, NF033889, COG5323 | NA | NA |
| UHGV-1545254_32 | KOfam | K00571 | E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] | NA |
| UHGV-1545254_32 | PHROG | phrog_498 | DNA methyltransferase | other |
| UHGV-1545254_32 | UniRef90 | UniRef90_A0A101WI32 | Methyltransferase | NA |
| UHGV-1545254_32 | eggNOG-mapper | 742823.HMPREF9465_00225 | PFAM DNA methylase N-4 N-6 | NA |
| UHGV-1545254_32 | PADLOC | MTase_II_00015 | Type II methyltransferase | RM |
| UHGV-1545254_32 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-1545254_32 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-1545254_32 | Structural annotation | PF01555, MF_01872, NF010253, COG0863 | NA | NA |
| UHGV-1545254_33 | KOfam | K03497 | parB, spo0J; ParB family transcriptional regulator, chromosome partitioning protein | NA |
| UHGV-1545254_33 | PHROG | phrog_498 | DNA methyltransferase | other |
| UHGV-1545254_33 | UniRef90 | UniRef90_A0A810PZK9 | ParB domain-containing protein | NA |
| UHGV-1545254_33 | eggNOG-mapper | 985665.HPL003_12065 | DNA methylase | NA |
| UHGV-1545254_33 | PADLOC | MTase_II_00015 | Type II methyltransferase | RM |
| UHGV-1545254_33 | Pfam | PF02195 | ParB/Sulfiredoxin domain | ParBc |
| UHGV-1545254_33 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-1545254_33 | Structural annotation | PF02195, TIGR00180, COG5119 | NA | NA |
| UHGV-1545254_34 | PHROG | phrog_36 | transcriptional regulator | transcription regulation |
| UHGV-1545254_34 | UniRef90 | UniRef90_UPI001C10AB33 | NA | NA |
| UHGV-1545254_34 | Structural annotation | PF07374, TIGR01636 | NA | NA |
| UHGV-1545254_43 | PHROG | phrog_374 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1545254_43 | UniRef90 | UniRef90_UPI0006891852 | AP2 domain-containing protein | NA |
| UHGV-1545254_43 | eggNOG-mapper | 1122149.BACN01000055_gene1942 | NA | NA |
| UHGV-1545254_44 | PHROG | phrog_1770 | Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-1545254_44 | UniRef90 | UniRef90_A0A533R9G2 | Holliday junction endonuclease | NA |
| UHGV-1545254_44 | eggNOG-mapper | 329726.AM1_4255 | Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group | NA |
| UHGV-1545254_44 | COG | COG0817 | Holliday junction resolvasome RuvABC endonuclease subunit RuvC | NA |
| UHGV-1545254_44 | Structural annotation | PF16921, MF_00034, NF000711, COG0817 | NA | NA |
| UHGV-1545254_45 | PHROG | phrog_16427 | DNA methyltransferase | other |
| UHGV-1545254_45 | UniRef90 | UniRef90_A0A3D5I9W8 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1545254_45 | eggNOG-mapper | 657322.FPR_23140 | DNA (cytosine-5-)-methyltransferase activity | NA |
| UHGV-1545254_45 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-1545254_45 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-1545254_46 | eggNOG-mapper | 657322.FPR_23130 | NA | NA |
| UHGV-1545254_48 | PHROG | phrog_18306 | NA | unknown function |
| UHGV-1545254_48 | Structural annotation | PF01423, MF_00257, NF001963, COG1958 | NA | NA |
| UHGV-1545254_49 | PHROG | phrog_16304 | NA | unknown function |
| UHGV-1545254_49 | UniRef90 | UniRef90_UPI001E560709 | NA | NA |
| UHGV-1545254_49 | eggNOG-mapper | 755731.Clo1100_1616 | Phage replisome organizer | NA |
| UHGV-1545254_49 | Pfam | PF19808 | NA | DUF6291 |
| UHGV-1545254_49 | COG | COG3935 | DNA replication protein DnaD | NA |
| UHGV-1545254_49 | Structural annotation | PF19808 | NA | NA |
| UHGV-1545254_50 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-1545254_50 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-1545254_50 | UniRef90 | UniRef90_A0A1C5PRE8 | Single-stranded DNA-binding protein | NA |
| UHGV-1545254_50 | eggNOG-mapper | 500632.CLONEX_02624 | Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism | NA |
| UHGV-1545254_50 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-1545254_50 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-1545254_50 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-1545254_50 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-1545254_50 | Structural annotation | PF00436, MF_00984, NF005580, COG0629 | NA | NA |
| UHGV-1545254_51 | KOfam | K07455 | recT; recombination protein RecT | NA |
| UHGV-1545254_51 | PHROG | phrog_148 | RecT-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-1545254_51 | UniRef90 | UniRef90_A0A3D3Y007 | Recombinase RecT | NA |
| UHGV-1545254_51 | eggNOG-mapper | 1226322.HMPREF1545_00015 | RecT family | NA |
| UHGV-1545254_51 | Pfam | PF03837 | RecT family | RecT |
| UHGV-1545254_51 | NCBIFam | TIGR00616.1 | recombinase, phage RecT family | NA |
| UHGV-1545254_51 | COG | COG3723 | Recombinational DNA repair protein RecT | NA |
| UHGV-1545254_51 | Structural annotation | PF03837, NF007351, COG3723 | NA | NA |
| UHGV-1545254_52 | PHROG | phrog_434 | RecE-like recombination exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1545254_52 | UniRef90 | UniRef90_A0A3D3XZF3 | YqaJ domain-containing protein | NA |
| UHGV-1545254_52 | eggNOG-mapper | 1121344.JHZO01000003_gene985 | YqaJ viral recombinase family | NA |
| UHGV-1545254_52 | Pfam | PF09588 | YqaJ-like viral recombinase domain | YqaJ |
| UHGV-1545254_52 | NCBIFam | TIGR03033.1 | putative phage-type endonuclease | NA |
| UHGV-1545254_52 | COG | COG5377 | Phage-related protein, predicted endonuclease | NA |
| UHGV-1545254_52 | Structural annotation | PF09588, MF_03030, TIGR03033, COG5377 | NA | NA |
| UHGV-1545254_62 | eggNOG-mapper | 1408323.JQKK01000005_gene152 | Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation | NA |
| UHGV-1545254_63 | eggNOG-mapper | 428127.EUBDOL_00130 | sequence-specific DNA binding | NA |
| UHGV-1545254_63 | COG | COG1476 | DNA-binding transcriptional regulator, XRE-family HTH domain | NA |
| UHGV-1545254_63 | Structural annotation | PF13443, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-1545254_64 | KOfam | K06400 | spoIVCA; site-specific DNA recombinase | NA |
| UHGV-1545254_64 | PHROG | phrog_95 | integrase | integration and excision |
| UHGV-1545254_64 | UniRef90 | UniRef90_A0A3A9I9T1 | Recombinase family protein | NA |
| UHGV-1545254_64 | eggNOG-mapper | 1378168.N510_03180 | resolvase | NA |
| UHGV-1545254_64 | Pfam | PF00239 | Resolvase, N terminal domain | Resolvase |
| UHGV-1545254_64 | Pfam | PF13408 | Recombinase zinc beta ribbon domain | Zn_ribbon_recom |
| UHGV-1545254_64 | COG | COG1961 | Site-specific DNA recombinase SpoIVCA/DNA invertase PinE | NA |
| UHGV-1545254_64 | Structural annotation | PF00239, NF041201, COG1961 | NA | NA |