| UHGV-0328676_1 | PHROG | phrog_144 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0328676_1 | UniRef90 | UniRef90_A0A1C6E832 | HNH endonuclease | NA |
| UHGV-0328676_1 | eggNOG-mapper | 469616.FMAG_00566 | HNH nucleases | NA |
| UHGV-0328676_1 | Structural annotation | PF05766 | NA | NA |
| UHGV-0328676_2 | PHROG | phrog_36 | transcriptional regulator | transcription regulation |
| UHGV-0328676_2 | UniRef90 | UniRef90_R5X6Q8 | Possible sigma factor | NA |
| UHGV-0328676_2 | eggNOG-mapper | 272562.CA_C0550 | sigma factor activity | NA |
| UHGV-0328676_2 | Pfam | PF04545 | Sigma-70, region 4 | Sigma70_r4 |
| UHGV-0328676_2 | NCBIFam | TIGR01636.1 | phage transcriptional regulator, RinA family | NA |
| UHGV-0328676_2 | COG | COG1191 | DNA-directed RNA polymerase specialized sigma subunit | NA |
| UHGV-0328676_2 | Structural annotation | PF08281, MF_00245, TIGR01636, COG1595 | NA | NA |
| UHGV-0328676_3 | KOfam | K06919 | K06919; putative DNA primase/helicase | NA |
| UHGV-0328676_3 | PHROG | phrog_864 | DNA primase | DNA, RNA and nucleotide metabolism |
| UHGV-0328676_3 | UniRef90 | UniRef90_A0A1C6GV86 | Phage/plasmid primase, P4 family, C-terminal domain | NA |
| UHGV-0328676_3 | eggNOG-mapper | 1304284.L21TH_2612 | TIGRFAM phage plasmid primase, P4 family, C-terminal domain | NA |
| UHGV-0328676_3 | Pfam | PF08706 | D5 N terminal like | D5_N |
| UHGV-0328676_3 | Pfam | PF19263 | NA | DUF5906 |
| UHGV-0328676_3 | Pfam | PF03288 | Poxvirus D5 protein-like | Pox_D5 |
| UHGV-0328676_3 | NCBIFam | TIGR01613.1 | phage/plasmid primase, P4 family | NA |
| UHGV-0328676_3 | COG | COG3378 | DNA primase, phage- or plasmid-associated | NA |
| UHGV-0328676_3 | Structural annotation | PF19263, PF08706, PF03288, PF09250, MF_04000, TIGR01613, COG3378 | NA | NA |
| UHGV-0328676_4 | PHROG | phrog_374 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0328676_4 | UniRef90 | UniRef90_A0A1C5YZ22 | HTH_Tnp_Tc3_1 domain-containing protein | NA |
| UHGV-0328676_4 | eggNOG-mapper | 1540091.A0A0A0RNF3_9CAUD | sequence-specific DNA binding transcription factor activity | NA |
| UHGV-0328676_4 | Structural annotation | PF02796, TIGR04381, COG2771 | NA | NA |
| UHGV-0328676_5 | KOfam | K03465 | thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148] | NA |
| UHGV-0328676_5 | PHROG | phrog_85 | thymidylate synthase | DNA, RNA and nucleotide metabolism |
| UHGV-0328676_5 | UniRef90 | UniRef90_A0A0R3K0J3 | Flavin-dependent thymidylate synthase | NA |
| UHGV-0328676_5 | eggNOG-mapper | 445973.CLOBAR_00072 | Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant | NA |
| UHGV-0328676_5 | Pfam | PF02511 | Thymidylate synthase complementing protein | Thy1 |
| UHGV-0328676_5 | NCBIFam | TIGR02170.1 | FAD-dependent thymidylate synthase | NA |
| UHGV-0328676_5 | COG | COG1351 | Thymidylate synthase ThyX, FAD-dependent family | NA |
| UHGV-0328676_5 | HAMAP | MF_01408 | Flavin-dependent thymidylate synthase [thyX] | NA |
| UHGV-0328676_5 | Structural annotation | PF02511, MF_01408, TIGR02170, COG1351 | NA | NA |
| UHGV-0328676_7 | PHROG | phrog_236 | nucleotide kinase | other |
| UHGV-0328676_7 | UniRef90 | UniRef90_UPI001EF8FBB2 | NA | NA |
| UHGV-0328676_7 | eggNOG-mapper | 673376.F2VHW0_9CAUD | NA | NA |
| UHGV-0328676_7 | Pfam | PF11753 | NA | DUF3310 |
| UHGV-0328676_8 | KOfam | K02319 | pol; DNA polymerase, archaea type [EC:2.7.7.7] | NA |
| UHGV-0328676_8 | PHROG | phrog_1252 | DNA polymerase | DNA, RNA and nucleotide metabolism |
| UHGV-0328676_8 | UniRef90 | UniRef90_A0A1C6GWY9 | DNA polymerase family B | NA |
| UHGV-0328676_8 | eggNOG-mapper | 445335.CBN_1360 | DNA polymerase elongation subunit (Family B) | NA |
| UHGV-0328676_8 | COG | COG0417 | DNA polymerase B elongation subunit | NA |
| UHGV-0328676_8 | Structural annotation | PF08490, MF_04100, TIGR00592, COG0417 | NA | NA |
| UHGV-0328676_9 | PHROG | phrog_7778 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0328676_9 | UniRef90 | UniRef90_UPI0009A7E289 | NA | NA |
| UHGV-0328676_9 | eggNOG-mapper | 1123288.SOV_6c01550 | NA | NA |
| UHGV-0328676_9 | Pfam | PF05037 | NA | DUF669 |
| UHGV-0328676_9 | Structural annotation | PF05037 | NA | NA |
| UHGV-0328676_10 | PHROG | phrog_155 | Erf-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0328676_10 | UniRef90 | UniRef90_UPI00052BC8F9 | ERF family protein | NA |
| UHGV-0328676_10 | eggNOG-mapper | 929506.CbC4_1193 | ERF superfamily | NA |
| UHGV-0328676_10 | Pfam | PF04404 | ERF superfamily | ERF |
| UHGV-0328676_11 | PHROG | phrog_93 | endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0328676_11 | UniRef90 | UniRef90_A0A1C6GW81 | VRR-NUC domain | NA |
| UHGV-0328676_11 | eggNOG-mapper | 203119.Cthe_1738 | VRR_NUC | NA |
| UHGV-0328676_11 | COG | COG1591 | Holliday junction resolvase Hjc, archaeal type | NA |
| UHGV-0328676_11 | Structural annotation | PF01870, MF_01490, NF040854, COG1591 | NA | NA |
| UHGV-0328676_12 | PHROG | phrog_6244 | NA | unknown function |
| UHGV-0328676_12 | UniRef90 | UniRef90_UPI0006C34CBC | siphovirus Gp157 family protein | NA |
| UHGV-0328676_12 | eggNOG-mapper | 1430331.EP10_02380 | YqaJ viral recombinase family | NA |
| UHGV-0328676_12 | COG | COG5377 | Phage-related protein, predicted endonuclease | NA |
| UHGV-0328676_12 | Structural annotation | PF05565 | NA | NA |
| UHGV-0328676_13 | KOfam | K14440 | SMARCAL1, HARP; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:5.6.2.-] | NA |
| UHGV-0328676_13 | PHROG | phrog_62 | DNA helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0328676_13 | UniRef90 | UniRef90_A0A1C6GWE5 | ATP-dependent helicase HepA | NA |
| UHGV-0328676_13 | eggNOG-mapper | 1280692.AUJL01000009_gene2982 | snf2 family | NA |
| UHGV-0328676_13 | PADLOC | DpdE_00003 | DpdE | DPD |
| UHGV-0328676_13 | Pfam | PF00176 | SNF2-related domain | SNF2-rel_dom |
| UHGV-0328676_13 | Pfam | PF00271 | Helicase conserved C-terminal domain | Helicase_C |
| UHGV-0328676_13 | COG | COG0553 | Superfamily II DNA or RNA helicase, SNF2 family | NA |
| UHGV-0328676_13 | Structural annotation | PF00176, PF00271, MF_01821, NF041790, COG0553 | NA | NA |
| UHGV-0328676_14 | KOfam | K18830 | pezA; HTH-type transcriptional regulator / antitoxin PezA | NA |
| UHGV-0328676_14 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-0328676_14 | UniRef90 | UniRef90_A0A446IBV6 | XRE family transcriptional regulator | NA |
| UHGV-0328676_14 | eggNOG-mapper | 999411.HMPREF1092_03286 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-0328676_14 | Pfam | PF12844 | Helix-turn-helix domain | HTH_19 |
| UHGV-0328676_14 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0328676_14 | Structural annotation | PF01381, MF_00535, NF007257, COG1476 | NA | NA |
| UHGV-0328676_16 | PHROG | phrog_59 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0328676_16 | UniRef90 | UniRef90_H9A140 | Homing HNH endonuclease | NA |
| UHGV-0328676_16 | eggNOG-mapper | 1147043.H9A140_9CAUD | HNH endonuclease | NA |
| UHGV-0328676_16 | Pfam | PF13392 | HNH endonuclease | HNH_3 |
| UHGV-0328676_20 | KOfam | K18640 | parM, stbA; plasmid segregation protein ParM | NA |
| UHGV-0328676_20 | PHROG | phrog_691 | partition protein | DNA, RNA and nucleotide metabolism |
| UHGV-0328676_20 | UniRef90 | UniRef90_UPI0005DE0931 | ParM/StbA family protein | NA |
| UHGV-0328676_20 | eggNOG-mapper | 536233.CLO_0569 | cell division | NA |
| UHGV-0328676_20 | Pfam | PF17989 | Actin like proteins N terminal domain | ALP_N |
| UHGV-0328676_20 | COG | COG0849 | Cell division ATPase FtsA | NA |
| UHGV-0328676_20 | Structural annotation | PF06723, MF_02207, NF010498, COG1077 | NA | NA |
| UHGV-0328676_23 | KOfam | K17398 | DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37] | NA |
| UHGV-0328676_23 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-0328676_23 | UniRef90 | UniRef90_T4V7T5 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-0328676_23 | eggNOG-mapper | 1235788.C802_00061 | C-5 cytosine-specific DNA methylase | NA |
| UHGV-0328676_23 | PADLOC | MTase_II_00058 | Type II methyltransferase | RM |
| UHGV-0328676_23 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-0328676_23 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-0328676_24 | PHROG | phrog_186 | DnaD-like helicase loader | DNA, RNA and nucleotide metabolism |
| UHGV-0328676_24 | UniRef90 | UniRef90_UPI0018A9C559 | DnaD domain protein | NA |
| UHGV-0328676_24 | eggNOG-mapper | 130478.Q9B0F9_9CAUD | calcium ion binding | NA |
| UHGV-0328676_24 | Structural annotation | PF13730, NF040939, COG5625 | NA | NA |
| UHGV-0328676_25 | KOfam | K00390 | cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] | NA |
| UHGV-0328676_25 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-0328676_25 | UniRef90 | UniRef90_A0A0U3EGR7 | Phosphoadenosine phosphosulfate reductase family protein | NA |
| UHGV-0328676_25 | eggNOG-mapper | 1345695.CLSA_c30150 | NA | NA |
| UHGV-0328676_25 | Pfam | PF01507 | Phosphoadenosine phosphosulfate reductase family | PAPS_reduct |
| UHGV-0328676_25 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-0328676_25 | Structural annotation | PF01507, MF_00063, NF006327, COG0175 | NA | NA |
| UHGV-0328676_28 | KOfam | K01447 | xlyAB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | NA |
| UHGV-0328676_28 | PHROG | phrog_3088 | amidase | lysis |
| UHGV-0328676_28 | UniRef90 | UniRef90_A0A7X9B8R6 | SH3 domain-containing protein | NA |
| UHGV-0328676_28 | eggNOG-mapper | 1396.DJ87_1663 | n-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0328676_28 | Pfam | PF01510 | N-acetylmuramoyl-L-alanine amidase | Amidase_2 |
| UHGV-0328676_28 | Pfam | PF08239 | Bacterial SH3 domain | SH3_3 |
| UHGV-0328676_28 | COG | COG5632 | N-acetylmuramoyl-L-alanine amidase CwlA | NA |
| UHGV-0328676_28 | Structural annotation | PF01510, PF18342, NF008758, NF033202, COG5632 | NA | NA |
| UHGV-0328676_29 | KOfam | K05996 | cpt; carboxypeptidase T [EC:3.4.17.18] | NA |
| UHGV-0328676_29 | PHROG | phrog_4722 | zinc carboxypeptidase | other |
| UHGV-0328676_29 | UniRef90 | UniRef90_UPI00112D5B96 | M14 family metallopeptidase | NA |
| UHGV-0328676_29 | eggNOG-mapper | 1406786.U5PVX3_9CAUD | metallocarboxypeptidase activity | NA |
| UHGV-0328676_29 | Pfam | PF10651 | BppU N-terminal domain | BppU_N |
| UHGV-0328676_29 | Pfam | PF00246 | Zinc carboxypeptidase | Peptidase_M14 |
| UHGV-0328676_30 | eggNOG-mapper | 1370121.AUWS01000008_gene5582 | Parallel beta-helix repeats | NA |
| UHGV-0328676_30 | Pfam | PF10651 | BppU N-terminal domain | BppU_N |
| UHGV-0328676_30 | Pfam | PF13229 | Right handed beta helix region | Beta_helix |
| UHGV-0328676_31 | PHROG | phrog_1067 | minor head protein | head and packaging |
| UHGV-0328676_31 | UniRef90 | UniRef90_UPI00164A835E | phage tail protein | NA |
| UHGV-0328676_31 | eggNOG-mapper | 999411.HMPREF1092_03309 | Prophage endopeptidase tail | NA |
| UHGV-0328676_31 | Pfam | PF18994 | Prophage endopeptidase tail N-terminal domain | Prophage_tailD1 |
| UHGV-0328676_31 | Pfam | PF06605 | Prophage endopeptidase tail | Prophage_tail |
| UHGV-0328676_31 | NCBIFam | TIGR01665.1 | phage tail spike protein | NA |
| UHGV-0328676_31 | COG | COG4926 | Phage-related protein | NA |
| UHGV-0328676_31 | Structural annotation | PF14594, TIGR01665, COG4926 | NA | NA |
| UHGV-0328676_32 | PHROG | phrog_33 | distal tail protein Dit | tail |
| UHGV-0328676_32 | UniRef90 | UniRef90_A0A1C6DMK9 | Phage-related protein | NA |
| UHGV-0328676_32 | eggNOG-mapper | 195103.CPF_1575 | tail component | NA |
| UHGV-0328676_32 | Pfam | PF05709 | Phage tail protein RIFT-related domain | Sipho_tail |
| UHGV-0328676_32 | NCBIFam | TIGR01633.1 | distal tail protein Dit | NA |
| UHGV-0328676_32 | COG | COG4722 | Phage-related protein YomH | NA |
| UHGV-0328676_32 | Structural annotation | PF20195, TIGR01633, COG4722 | NA | NA |
| UHGV-0328676_33 | KOfam | K22804 | SMC6; structural maintenance of chromosomes protein 6 | NA |
| UHGV-0328676_33 | PHROG | phrog_1272 | tail length tape measure protein | tail |
| UHGV-0328676_33 | eggNOG-mapper | 1536774.H70357_10670 | minor tail protein | NA |
| UHGV-0328676_33 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-0328676_33 | COG | COG5280 | Phage-related minor tail protein | NA |
| UHGV-0328676_33 | Structural annotation | PF10145, PF05384, TIGR01760, TIGR02559, COG5280 | NA | NA |
| UHGV-0328676_34 | Structural annotation | PF11836 | NA | NA |
| UHGV-0328676_35 | PHROG | phrog_88 | major tail protein | tail |
| UHGV-0328676_35 | eggNOG-mapper | 1414720.CBYM010000049_gene117 | phage major tail protein, phi13 family | NA |
| UHGV-0328676_35 | Structural annotation | PF04630, TIGR01603, COG3498 | NA | NA |
| UHGV-0328676_36 | eggNOG-mapper | 536233.CLO_1367 | NA | NA |
| UHGV-0328676_36 | Structural annotation | PF05657 | NA | NA |
| UHGV-0328676_37 | UniRef90 | UniRef90_UPI0018AAD4F8 | HK97 gp10 family phage protein | NA |
| UHGV-0328676_37 | Structural annotation | TIGR01725 | NA | NA |
| UHGV-0328676_38 | PHROG | phrog_25 | head closure Hc1 | connector |
| UHGV-0328676_38 | UniRef90 | UniRef90_A0A336Q665 | Phage head-tail adaptor | NA |
| UHGV-0328676_38 | eggNOG-mapper | 536233.CLO_1365 | Phage head-tail joining protein | NA |
| UHGV-0328676_38 | Pfam | PF05521 | Phage head-tail joining protein | Phage_H_T_join |
| UHGV-0328676_38 | NCBIFam | TIGR01563.1 | phage head closure protein | NA |
| UHGV-0328676_38 | Structural annotation | PF05521, TIGR01563, COG5614 | NA | NA |
| UHGV-0328676_43 | PHROG | phrog_10 | major head protein | head and packaging |
| UHGV-0328676_43 | UniRef90 | UniRef90_A0A1C6F7A6 | Predicted phage phi-C31 gp36 major capsid-like protein | NA |
| UHGV-0328676_43 | eggNOG-mapper | 1423755.BAML01000004_gene383 | Phage capsid family | NA |
| UHGV-0328676_43 | Pfam | PF05065 | Phage capsid family | Phage_capsid |
| UHGV-0328676_43 | NCBIFam | TIGR01554.2 | phage major capsid protein | NA |
| UHGV-0328676_43 | COG | COG4653 | Predicted phage phi-C31 gp36 major capsid-like protein | NA |
| UHGV-0328676_43 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0328676_44 | KOfam | K01358 | clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] | NA |
| UHGV-0328676_44 | PHROG | phrog_94 | head maturation protease | head and packaging |
| UHGV-0328676_44 | UniRef90 | UniRef90_A0A0Q7K8Z7 | ATP-dependent Clp protease proteolytic subunit | NA |
| UHGV-0328676_44 | eggNOG-mapper | 1124578.H0USW5_9CAUD | Clp protease | NA |
| UHGV-0328676_44 | Pfam | PF00574 | Clp protease | CLP_protease |
| UHGV-0328676_44 | Structural annotation | PF00574, MF_00444, NF011090, COG0740 | NA | NA |
| UHGV-0328676_45 | PHROG | phrog_12 | portal protein | head and packaging |
| UHGV-0328676_45 | UniRef90 | UniRef90_A0A1C6E8K9 | Phage portal protein, HK97 family | NA |
| UHGV-0328676_45 | eggNOG-mapper | 536232.CLM_2933 | Phage portal protein, HK97 family | NA |
| UHGV-0328676_45 | Pfam | PF04860 | Phage portal protein | Phage_portal |
| UHGV-0328676_45 | NCBIFam | TIGR01537.1 | phage portal protein | NA |
| UHGV-0328676_45 | COG | COG4695 | Phage portal protein BeeE | NA |
| UHGV-0328676_45 | Structural annotation | PF04860, MF_04135, TIGR01537, COG4695 | NA | NA |
| UHGV-0328676_47 | PHROG | phrog_9 | terminase large subunit | head and packaging |
| UHGV-0328676_47 | UniRef90 | UniRef90_A0A150FQX1 | Terminase | NA |
| UHGV-0328676_47 | eggNOG-mapper | 1567010.A0A0A7RU73_9VIRU | Phage Terminase | NA |
| UHGV-0328676_47 | Pfam | PF03354 | Terminase large subunit, ATPase domain | TerL_ATPase |
| UHGV-0328676_47 | Pfam | PF20441 | Terminase large subunit, endonuclease domain | TerL_nuclease |
| UHGV-0328676_47 | Structural annotation | PF20441, PF03354, MF_04146, TIGR01547, COG4626 | NA | NA |
| UHGV-0328676_48 | PHROG | phrog_83 | terminase small subunit | head and packaging |
| UHGV-0328676_48 | UniRef90 | UniRef90_UPI0018AA8382 | phage terminase small subunit P27 family | NA |
| UHGV-0328676_48 | eggNOG-mapper | 1291050.JAGE01000001_gene2918 | phage terminase small subunit | NA |
| UHGV-0328676_48 | Pfam | PF05119 | Phage terminase, small subunit | Terminase_4 |
| UHGV-0328676_48 | NCBIFam | TIGR01558.1 | phage terminase small subunit P27 family | NA |
| UHGV-0328676_48 | COG | COG3747 | Phage terminase, small subunit | NA |
| UHGV-0328676_48 | Structural annotation | PF05119, TIGR01558, COG3747 | NA | NA |