| UHGV-0080454_2 | KOfam | K21498 | higA-1; antitoxin HigA-1 | NA |
| UHGV-0080454_2 | PHROG | phrog_2439 | transcriptional regulator | transcription regulation |
| UHGV-0080454_2 | UniRef90 | UniRef90_A0A1G4S278 | Addiction module antidote protein, HigA family | NA |
| UHGV-0080454_2 | eggNOG-mapper | 411469.EUBHAL_00045 | antidote protein | NA |
| UHGV-0080454_2 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0080454_2 | COG | COG3093 | Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain | NA |
| UHGV-0080454_3 | eggNOG-mapper | 373903.Hore_18550 | Peptidoglycan-binding domain 1 protein | NA |
| UHGV-0080454_3 | COG | COG1376 | Lipoprotein-anchoring transpeptidase ErfK/SrfK | NA |
| UHGV-0080454_3 | Structural annotation | PF03734, NF007563, COG1376 | NA | NA |
| UHGV-0080454_5 | UniRef90 | UniRef90_UPI001EDD344B | phage holin family protein | NA |
| UHGV-0080454_5 | eggNOG-mapper | 1009370.ALO_09224 | Bacteriophage holin family | NA |
| UHGV-0080454_5 | Pfam | PF05105 | Bacteriophage holin family | Phage_holin_4_1 |
| UHGV-0080454_7 | PHROG | phrog_2837 | tail protein | tail |
| UHGV-0080454_7 | UniRef90 | UniRef90_UPI001032F78F | NA | NA |
| UHGV-0080454_7 | eggNOG-mapper | 1009370.ALO_04638 | NA | NA |
| UHGV-0080454_7 | Pfam | PF14301 | NA | DUF4376 |
| UHGV-0080454_7 | Structural annotation | PF14301 | NA | NA |
| UHGV-0080454_9 | KOfam | K16628 | COL7A; collagen type VII alpha | NA |
| UHGV-0080454_9 | PHROG | phrog_819 | tail protein | tail |
| UHGV-0080454_9 | Pfam | PF01391 | Collagen triple helix repeat (20 copies) | Collagen |
| UHGV-0080454_11 | PHROG | phrog_7940 | NA | unknown function |
| UHGV-0080454_11 | UniRef90 | UniRef90_A0A316S9G6 | Toxin Bro | NA |
| UHGV-0080454_11 | eggNOG-mapper | 546271.Selsp_1341 | BRO family, N-terminal domain | NA |
| UHGV-0080454_11 | Pfam | PF02498 | BRO family, N-terminal domain | Bro-N |
| UHGV-0080454_11 | COG | COG3617 | Prophage antirepressor | NA |
| UHGV-0080454_11 | Structural annotation | PF10543 | NA | NA |
| UHGV-0080454_13 | KOfam | K22299 | rghR; HTH-type transcriptional regulator, competence development regulator | NA |
| UHGV-0080454_13 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-0080454_13 | UniRef90 | UniRef90_A0A412X6X2 | XRE family transcriptional regulator | NA |
| UHGV-0080454_13 | eggNOG-mapper | 1378168.N510_02065 | sequence-specific DNA binding | NA |
| UHGV-0080454_13 | PADLOC | retron_type_VI_hth_cluster2_1 | NA | Retron |
| UHGV-0080454_13 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0080454_13 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0080454_14 | UniRef90 | UniRef90_UPI001C3783F9 | YHYH domain-containing protein | NA |
| UHGV-0080454_14 | NCBIFam | NF033223.2 | YHYH domain-containing protein | NA |
| UHGV-0080454_14 | COG | COG0103 | Ribosomal protein S9 | NA |
| UHGV-0080454_15 | PHROG | phrog_9880 | NA | unknown function |
| UHGV-0080454_15 | UniRef90 | UniRef90_A0A7X2XH87 | MuF_C domain-containing protein | NA |
| UHGV-0080454_15 | eggNOG-mapper | 1123288.SOV_1c10750 | NA | NA |
| UHGV-0080454_15 | Pfam | PF18819 | Phage MuF-C-terminal domain | MuF_C |
| UHGV-0080454_18 | PHROG | phrog_308 | internal virion protein | head and packaging |
| UHGV-0080454_19 | PHROG | phrog_376 | tail protein | tail |
| UHGV-0080454_19 | eggNOG-mapper | 568816.Acin_1828 | NA | NA |
| UHGV-0080454_19 | Structural annotation | PF04053, PF13157, MF_03056, NF038015, COG2706 | NA | NA |
| UHGV-0080454_20 | PHROG | phrog_376 | tail protein | tail |
| UHGV-0080454_20 | eggNOG-mapper | 585503.HMPREF7545_1740 | NA | NA |
| UHGV-0080454_21 | PHROG | phrog_394 | tail protein | tail |
| UHGV-0080454_21 | eggNOG-mapper | 883080.HMPREF9697_04026 | NA | NA |
| UHGV-0080454_21 | Structural annotation | PF17212 | NA | NA |
| UHGV-0080454_24 | PHROG | phrog_212 | major head protein | head and packaging |
| UHGV-0080454_24 | UniRef90 | UniRef90_A0A0M3F638 | NA | NA |
| UHGV-0080454_24 | eggNOG-mapper | 82995.CR62_16685 | NA | NA |
| UHGV-0080454_24 | Pfam | PF20911 | Major capsid protein GP7 | GP7 |
| UHGV-0080454_24 | Structural annotation | PF20911, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0080454_26 | PHROG | phrog_528 | NA | unknown function |
| UHGV-0080454_27 | PHROG | phrog_332 | head-tail adaptor | connector |
| UHGV-0080454_27 | UniRef90 | UniRef90_UPI0010329B07 | portal protein | NA |
| UHGV-0080454_27 | eggNOG-mapper | 1072685.IX83_07100 | Bacteriophage head to tail connecting protein | NA |
| UHGV-0080454_27 | Pfam | PF12236 | Bacteriophage head to tail connecting protein | Head-tail_con |
| UHGV-0080454_27 | Structural annotation | PF12236, MF_04120, TIGR01538, COG4695 | NA | NA |
| UHGV-0080454_29 | PHROG | phrog_5902 | NA | unknown function |
| UHGV-0080454_29 | UniRef90 | UniRef90_UPI001032D579 | terminase | NA |
| UHGV-0080454_29 | eggNOG-mapper | 1485543.JMME01000020_gene792 | Terminase RNaseH-like domain | NA |
| UHGV-0080454_29 | COG | COG0507 | ATPase/5'-3' helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) | NA |
| UHGV-0080454_29 | Structural annotation | PF03237, PF20441, MF_04145, TIGR01547, COG1783 | NA | NA |
| UHGV-0080454_30 | PHROG | phrog_309 | terminase small subunit | head and packaging |
| UHGV-0080454_30 | UniRef90 | UniRef90_A0A7X3BWM5 | Helix-turn-helix domain-containing protein | NA |
| UHGV-0080454_30 | eggNOG-mapper | 698769.JFBD01000002_gene2747 | transposase activity | NA |
| UHGV-0080454_30 | Pfam | PF13384 | Homeodomain-like domain | HTH_23 |
| UHGV-0080454_30 | COG | COG2963 | Transposase InsE and inactivated derivatives | NA |
| UHGV-0080454_30 | Structural annotation | PF07141 | NA | NA |
| UHGV-0080454_32 | PHROG | phrog_419 | NA | unknown function |
| UHGV-0080454_32 | UniRef90 | UniRef90_A0A4U9RIR3 | NA | NA |
| UHGV-0080454_32 | eggNOG-mapper | 476272.RUMHYD_01760 | NA | NA |
| UHGV-0080454_32 | Structural annotation | PF14083 | NA | NA |
| UHGV-0080454_33 | eggNOG-mapper | 401526.TcarDRAFT_1279 | phage transcriptional regulator, RinA family | NA |
| UHGV-0080454_33 | Structural annotation | PF05263, MF_00245, TIGR01636, COG2739 | NA | NA |
| UHGV-0080454_35 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-0080454_35 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0080454_35 | UniRef90 | UniRef90_UPI000F0C363F | single-stranded DNA-binding protein | NA |
| UHGV-0080454_35 | eggNOG-mapper | 1262914.BN533_00181 | Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism | NA |
| UHGV-0080454_35 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-0080454_35 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-0080454_35 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-0080454_35 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-0080454_35 | Structural annotation | PF00436, MF_00984, NF005580, COG0629 | NA | NA |
| UHGV-0080454_41 | PHROG | phrog_8538 | NA | unknown function |
| UHGV-0080454_41 | eggNOG-mapper | 1009370.ALO_12631 | NA | NA |
| UHGV-0080454_42 | PHROG | phrog_190 | Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-0080454_42 | UniRef90 | UniRef90_A0A7X2XHQ8 | NA | NA |
| UHGV-0080454_42 | eggNOG-mapper | 1347392.CCEZ01000043_gene417 | NA | NA |
| UHGV-0080454_42 | Pfam | PF06356 | NA | DUF1064 |
| UHGV-0080454_42 | Structural annotation | PF06356, NF033179 | NA | NA |
| UHGV-0080454_44 | PHROG | phrog_954 | DNA methyltransferase | other |
| UHGV-0080454_44 | UniRef90 | UniRef90_A0A2A4H9K2 | SAM-dependent methyltransferase | NA |
| UHGV-0080454_44 | eggNOG-mapper | 2754.EH55_06965 | Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA | NA |
| UHGV-0080454_44 | PADLOC | MTase_II_00074 | Type II methyltransferase | RM |
| UHGV-0080454_44 | COG | COG1092 | 23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI | NA |
| UHGV-0080454_44 | Structural annotation | PF01170, MF_01057, TIGR00446, COG4123 | NA | NA |
| UHGV-0080454_45 | PHROG | phrog_9298 | radical SAM domain protein | other |
| UHGV-0080454_45 | eggNOG-mapper | 457424.BFAG_02406 | radical SAM domain protein | NA |
| UHGV-0080454_45 | COG | COG1032 | Radical SAM superfamily enzyme YgiQ, UPF0313 family | NA |
| UHGV-0080454_47 | PHROG | phrog_7964 | NA | unknown function |
| UHGV-0080454_47 | UniRef90 | UniRef90_UPI00103291C8 | polymer-forming cytoskeletal protein | NA |
| UHGV-0080454_47 | eggNOG-mapper | 411470.RUMGNA_02189 | Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell | NA |
| UHGV-0080454_47 | Pfam | PF18836 | YdcK Beta solenoid repeat | B_solenoid_ydck |
| UHGV-0080454_47 | COG | COG1044 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase | NA |
| UHGV-0080454_47 | Structural annotation | NF040481, COG2171 | NA | NA |
| UHGV-0080454_49 | KOfam | K02314 | dnaB; replicative DNA helicase [EC:5.6.2.3] | NA |
| UHGV-0080454_49 | PHROG | phrog_19 | DnaB-like replicative helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0080454_49 | UniRef90 | UniRef90_A0A7X3BWY1 | DNA helicase | NA |
| UHGV-0080454_49 | eggNOG-mapper | 1485543.JMME01000021_gene800 | DnaB-like helicase N terminal domain | NA |
| UHGV-0080454_49 | Pfam | PF00772 | DnaB-like helicase N terminal domain | DnaB |
| UHGV-0080454_49 | Pfam | PF03796 | DnaB-like helicase C terminal domain | DnaB_C |
| UHGV-0080454_49 | COG | COG0305 | Replicative DNA helicase | NA |
| UHGV-0080454_50 | PHROG | phrog_11769 | NA | unknown function |
| UHGV-0080454_50 | UniRef90 | UniRef90_A0A7X3BW49 | DnaD domain protein | NA |
| UHGV-0080454_50 | eggNOG-mapper | 1567013.A0A0A7RTL4_9CAUD | calcium ion binding | NA |
| UHGV-0080454_50 | Pfam | PF09681 | N-terminal phage replisome organiser (Phage_rep_org_N) | Phage_rep_org_N |
| UHGV-0080454_50 | NCBIFam | TIGR01714.1 | phage replisome organizer, putative, N-terminal region | NA |
| UHGV-0080454_50 | Structural annotation | PF09681, TIGR01714, COG3388 | NA | NA |
| UHGV-0080454_51 | PHROG | phrog_7566 | NA | unknown function |
| UHGV-0080454_51 | eggNOG-mapper | 1280698.AUJS01000007_gene1020 | NA | NA |
| UHGV-0080454_52 | PHROG | phrog_72 | NinB/ Orf homologous recombination mediator | DNA, RNA and nucleotide metabolism |
| UHGV-0080454_52 | UniRef90 | UniRef90_A0A8D9PDS2 | NinB protein | NA |
| UHGV-0080454_52 | eggNOG-mapper | 508419.F8J186_9CAUD | NA | NA |
| UHGV-0080454_54 | PHROG | phrog_2324 | Erf-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0080454_54 | UniRef90 | UniRef90_UPI001402D75D | ERF family protein | NA |
| UHGV-0080454_54 | eggNOG-mapper | 1209989.TepiRe1_1126 | ERF superfamily | NA |
| UHGV-0080454_54 | Pfam | PF04404 | ERF superfamily | ERF |
| UHGV-0080454_54 | Structural annotation | PF04404, TIGR00607, COG5055 | NA | NA |
| UHGV-0080454_59 | PHROG | phrog_7338 | NA | unknown function |
| UHGV-0080454_59 | UniRef90 | UniRef90_A0A1G6KQV8 | DNA binding domain-containing protein, excisionase family | NA |
| UHGV-0080454_59 | eggNOG-mapper | 273068.TTE2123 | Excisionase from transposon Tn916 | NA |
| UHGV-0080454_59 | Structural annotation | PF09035, TIGR01764, COG3311 | NA | NA |
| UHGV-0080454_63 | UniRef90 | UniRef90_U7UK22 | Ribbon-helix-helix protein, CopG family | NA |
| UHGV-0080454_63 | Pfam | PF03869 | Arc-like DNA binding domain | Arc |
| UHGV-0080454_64 | PHROG | phrog_2657 | transcriptional regulator | transcription regulation |
| UHGV-0080454_64 | UniRef90 | UniRef90_UPI001032BCDE | Rha family transcriptional regulator | NA |
| UHGV-0080454_64 | eggNOG-mapper | 1089548.KI783301_gene2640 | Phage regulatory protein Rha (Phage_pRha) | NA |
| UHGV-0080454_64 | Pfam | PF09669 | Phage regulatory protein Rha (Phage_pRha) | Phage_pRha |
| UHGV-0080454_64 | NCBIFam | TIGR02681.1 | phage regulatory protein, Rha family | NA |
| UHGV-0080454_64 | COG | COG3646 | Phage regulatory protein Rha | NA |
| UHGV-0080454_64 | Structural annotation | PF09669, TIGR02681, COG3646 | NA | NA |
| UHGV-0080454_65 | KOfam | K07729 | K07729; putative transcriptional regulator | NA |
| UHGV-0080454_65 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-0080454_65 | UniRef90 | UniRef90_UPI0010FD1F0E | helix-turn-helix transcriptional regulator | NA |
| UHGV-0080454_65 | eggNOG-mapper | 997350.HMPREF9129_1690 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-0080454_65 | PADLOC | retron_type_VI_hth_cluster2_1 | NA | Retron |
| UHGV-0080454_65 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0080454_65 | COG | COG1476 | DNA-binding transcriptional regulator, XRE-family HTH domain | NA |
| UHGV-0080454_65 | Structural annotation | PF01381, NF041951, COG1476 | NA | NA |
| UHGV-0080454_66 | KOfam | K22299 | rghR; HTH-type transcriptional regulator, competence development regulator | NA |
| UHGV-0080454_66 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-0080454_66 | UniRef90 | UniRef90_UPI00047E223F | helix-turn-helix domain-containing protein | NA |
| UHGV-0080454_66 | eggNOG-mapper | 340099.Teth39_0032 | PFAM helix-turn-helix domain protein | NA |
| UHGV-0080454_66 | PADLOC | retron_type_VI_hth_cluster2_1 | NA | Retron |
| UHGV-0080454_66 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0080454_66 | COG | COG1476 | DNA-binding transcriptional regulator, XRE-family HTH domain | NA |
| UHGV-0080454_66 | Structural annotation | PF01381, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-0080454_67 | Structural annotation | PF06114 | NA | NA |
| UHGV-0080454_69 | eggNOG-mapper | 1005994.GTGU_01419 | NA | NA |
| UHGV-0080454_70 | KOfam | K07171 | mazF, ndoA, chpA; mRNA interferase MazF [EC:3.1.-.-] | NA |
| UHGV-0080454_70 | PHROG | phrog_1412 | antitoxin mazE-like | moron, auxiliary metabolic gene and host takeover |
| UHGV-0080454_70 | UniRef90 | UniRef90_UPI000F8EB2AD | type II toxin-antitoxin system PemK/MazF family toxin | NA |
| UHGV-0080454_70 | eggNOG-mapper | 1235792.C808_05257 | Toxic component of a toxin-antitoxin (TA) module | NA |
| UHGV-0080454_70 | Pfam | PF02452 | PemK-like, MazF-like toxin of type II toxin-antitoxin system | PemK_toxin |
| UHGV-0080454_70 | COG | COG2337 | mRNA-degrading endonuclease MazF, toxin component of the MazEF toxin-antitoxin module | NA |
| UHGV-0080454_70 | Structural annotation | PF02452, NF007386, COG2337 | NA | NA |
| UHGV-0080454_71 | PHROG | phrog_2657 | transcriptional regulator | transcription regulation |
| UHGV-0080454_71 | UniRef90 | UniRef90_UPI0003FD2D49 | KilA-N domain-containing protein | NA |
| UHGV-0080454_71 | eggNOG-mapper | 653733.Selin_1708 | AntA/AntB antirepressor | NA |
| UHGV-0080454_71 | Pfam | PF04383 | KilA-N domain | KilA-N |
| UHGV-0080454_71 | COG | COG3561 | Phage anti-repressor protein Ant | NA |
| UHGV-0080454_71 | Structural annotation | PF04383, NF033622, COG3943 | NA | NA |
| UHGV-0080454_72 | KOfam | K14059 | int; integrase | NA |
| UHGV-0080454_72 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-0080454_72 | UniRef90 | UniRef90_G9YK08 | Site-specific recombinase, phage integrase family | NA |
| UHGV-0080454_72 | eggNOG-mapper | 861450.HMPREF0080_02017 | Belongs to the 'phage' integrase family | NA |
| UHGV-0080454_72 | Pfam | PF14659 | Phage integrase, N-terminal SAM-like domain | Phage_int_SAM_3 |
| UHGV-0080454_72 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-0080454_72 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-0080454_72 | Structural annotation | PF00589, PF14659, MF_02055, TIGR02224, COG4974 | NA | NA |